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Results for “Familial Hyperlipoproteinemia Type 1”

44 trials

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Showing 20 of 44 results

Large-scale testing (Phase 3)Study completedNCT02658175
What this trial is testing

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 68
Testing effectiveness (Phase 2)Study completedNCT02767531
What this trial is testing

Orlistat for the Treatment of Type I Hyperlipoproteinemia

Who this might be right for
Hyperlipoproteinemia Type IHypertriglyceridemia
University of Texas Southwestern Medical Center 2
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9
Not applicableStudy completedNCT02656095
What this trial is testing

Lipoprotein Lipase Enzyme Activity Assay Validation and Clinical Assessment

Who this might be right for
Lipoprotein Lipase Deficiency
University of Colorado, Denver 12
Testing effectiveness (Phase 2)Study completedNCT03360747
What this trial is testing

Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 3
Testing effectiveness (Phase 2)Study completedNCT01146522
What this trial is testing

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Who this might be right for
Hyperlipoproteinemia
Novartis Pharmaceuticals 8
Large-scale testing (Phase 3)Study completedNCT00891306
What this trial is testing

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 5
Not applicableApproved For MarketingNCT06360237
What this trial is testing

Olezarsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc.
Very early researchLooking for participantsNCT07371767
What this trial is testing

CS-121 APOC3 Base Editing in Children and Adolescents With Hyperchylomicronemia

Who this might be right for
Hyperchylomicronemia
Shanghai Jiao Tong University School of Medicine 15
Not applicableStudy completedNCT02750527
What this trial is testing

Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany

Who this might be right for
Type 1 DiabetesFamilial Hypercholesterolemia
Kinderkrankenhaus auf der Bult 13,049
Not applicableStudy completedNCT03912181
What this trial is testing

Medical Complications in Familial and Multifactorial Chylomicronaemia Syndromes

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
Hospices Civils de Lyon 140
Not applicableEnded earlyNCT01447901
What this trial is testing

Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies

Who this might be right for
Hyperlipoproteinemia Type I
Amsterdam Molecular Therapeutics 19
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS

Who this might be right for
Familial ChylomicronemiaHigh Risk Severe Hypertriglyceridemia (SHTG)
Arrowhead Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Large-scale testing (Phase 3)Study completedNCT01514461
What this trial is testing

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
Novartis Pharmaceuticals 45
Early research (Phase 1)Study completedNCT05851066
What this trial is testing

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Visirna Therapeutics HK Limited 36
Not applicableLooking for participantsNCT07086989
What this trial is testing

Cardiovascular Risk in Children With Chronic Conditions Study

Who this might be right for
Kidney TransplantFamilial HypercholesterolaemiaType 1 Diabetes Mellitus (T1DM)+22 more
Semmelweis University 300
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Not applicableNot Yet RecruitingNCT07606118
What this trial is testing

An Observational Study to Evaluate Treatment Patterns in High, Very High and Extreme Cardiovascular Risk Patients With Hypercholesterolemia, Including Familial Hypercholesterolemia

Who this might be right for
HypercholesterolaemiaFamilial HypercholesterolaemiaCVD Risk
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 2,500
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