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Results for “Familial Hyperlipoproteinemia Type 1”

42 trials

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Showing 20 of 42 results

Large-scale testing (Phase 3)Study completedNCT02658175
What this trial is testing

The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 68
Not applicableStudy completedNCT03912181
What this trial is testing

Medical Complications in Familial and Multifactorial Chylomicronaemia Syndromes

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
Hospices Civils de Lyon 140
Large-scale testing (Phase 3)Active Not RecruitingNCT05185843
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 24
Large-scale testing (Phase 3)Study completedNCT00891306
What this trial is testing

Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects

Who this might be right for
Familial Lipoprotein Lipase Deficiency
Amsterdam Molecular Therapeutics 5
Very early researchLooking for participantsNCT07371767
What this trial is testing

CS-121 APOC3 Base Editing in Children and Adolescents With Hyperchylomicronemia

Who this might be right for
Hyperchylomicronemia
Shanghai Jiao Tong University School of Medicine 15
Large-scale testing (Phase 3)Active Not RecruitingNCT05130450
What this trial is testing

Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 60
Not applicableAvailableNCT06796426
What this trial is testing

Treatment Protocol of Plozasiran in Adults and Adolescents With FCS

Who this might be right for
Familial Chylomicronemia
Arrowhead Pharmaceuticals
Very early researchLooking for participantsNCT07176923
What this trial is testing

CS-121 APOC3 Base Editing in FCS

Who this might be right for
Familial Chylomicronemia Syndrome (FCS)
CorrectSequence Therapeutics Co., Ltd 15
Not applicableStudy completedNCT04223908
What this trial is testing

InFocus France Epidemiological Study of Health Burden in Major Hypertriglyceridemia

Who this might be right for
Familial Chylomicronemia SyndromeMultifactorial Chylomicronemia Syndrome
New French Society of Atherosclerosis 52
Not applicableNo Longer AvailableNCT03544060
What this trial is testing

Volanesorsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia
Akcea Therapeutics
Testing effectiveness (Phase 2)Study completedNCT03360747
What this trial is testing

Phase 2 Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia SyndromeLipoprotein Lipase DeficiencyHyperlipoproteinemia Type 1
Akcea Therapeutics 3
Large-scale testing (Phase 3)Active Not RecruitingNCT05089084
What this trial is testing

Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
Familial Chylomicronemia
Arrowhead Pharmaceuticals 75
Early research (Phase 1)Study completedNCT03783377
What this trial is testing

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Who this might be right for
HypertriglyceridemiaFamilial Chylomicronemia
Arrowhead Pharmaceuticals 112
Testing effectiveness (Phase 2)Ended earlyNCT01675154
What this trial is testing

Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 Hyperlipoproteinemia

Who this might be right for
Type 1 Hyperlipoproteinemia
University of Texas Southwestern Medical Center 5
Early research (Phase 1)Study completedNCT05851066
What this trial is testing

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Visirna Therapeutics HK Limited 36
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Not applicableActive Not RecruitingNCT04656028
What this trial is testing

Genetic Testing and Motivational Counseling for FH

Who this might be right for
Hypercholesterolemia, FamilialHypercholesterolemia, Familial, 1Hypercholesterolemia, Familial, 2+23 more
National Medical Research Center for Therapy and Preventive Medicine 180
Early research (Phase 1)Study completedNCT03747224
What this trial is testing

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Arrowhead Pharmaceuticals 93
Large-scale testing (Phase 3)Study completedNCT02211209
What this trial is testing

The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome

Who this might be right for
Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals, Inc. 67
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
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