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Results for “Fibrodysplasia Ossificans Progressiva”

24 trials

Showing 20 of 24 results

Testing effectiveness (Phase 2)Ended earlyNCT05039515
What this trial is testing

Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP).

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 113
Not applicableStudy completedNCT06064656
What this trial is testing

A Non-Interventional Study of Clinical Characteristics and Mortality of US Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Regeneron Pharmaceuticals 131
Large-scale testing (Phase 3)Active Not RecruitingNCT06508021
What this trial is testing

Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Ashibio Inc 92
Testing effectiveness (Phase 2)Study completedNCT02190747
What this trial is testing

An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 40
Not applicableStudy completedNCT02066324
What this trial is testing

Urine Sample Collection From FOP Patients

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Novartis Pharmaceuticals 25
Not applicableLooking for participantsNCT06089616
What this trial is testing

Document and to Further Describe Long-term Safety and Effectiveness of Palovarotene in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Ipsen 100
Large-scale testing (Phase 3)Active Not RecruitingNCT05394116
What this trial is testing

Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Regeneron Pharmaceuticals 63
Not applicableLooking for participantsNCT06724562
What this trial is testing

IL1 Inhibition in FOP

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
University of California, San Francisco 11
Not applicableStudy completedNCT04665323
What this trial is testing

An International Cross-sectional Survey to Evaluate the Burden of Fibrodysplasia Ossificans Progressiva (FOP) on Patients and Their Families.

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Ipsen 411
Not applicableStudy completedNCT02322255
What this trial is testing

A Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 114
Large-scale testing (Phase 3)WithdrawnNCT04577820
What this trial is testing

Study to Assess the Efficacy and Safety of Garetosmab in Japanese Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodyplasia Ossificans Progressiva (FOP)Heterotopic Ossification (HO)
Regeneron Pharmaceuticals
Early research (Phase 1)Study completedNCT04829773
What this trial is testing

Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult Subjects

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 48
Large-scale testing (Phase 3)Study completedNCT03312634
What this trial is testing

An Efficacy and Safety Study of Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva.

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 107
Not applicableTemporarily Not AvailableNCT07301450
What this trial is testing

An Expanded Access Program of Garetosmab in Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT05090891
What this trial is testing

To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Incyte Corporation 98
Testing effectiveness (Phase 2)Study completedNCT03188666
What this trial is testing

Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Regeneron Pharmaceuticals 44
Early research (Phase 1)Study completedNCT04818398
What this trial is testing

Study of Single-Ascending Doses of DS-6016a in Healthy Japanese Subjects

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Daiichi Sankyo Co., Ltd. 48
Large-scale testing (Phase 3)Study completedNCT05027802
What this trial is testing

A Rollover Study to Further Evaluate the Safety and Efficacy of Palovarotene Capsules in Male and Female Participants Aged ≥14 Years With Fibrodysplasia Ossificans Progressiva (FOP) Who Have Completed the Relevant Parent Studies.

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Ipsen 61
Testing effectiveness (Phase 2)Active Not RecruitingNCT04307953
What this trial is testing

Saracatinib Trial TO Prevent FOP

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Amsterdam UMC, location VUmc 20
Early research (Phase 1)Study completedNCT05099445
What this trial is testing

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis

Who this might be right for
Renal ImpairmentHemodialysis
Incyte Corporation 48
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