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Results for “Fibrodysplasia Ossificans Progressiva (FOP)”

24 trials

Showing 20 of 24 results

Large-scale testing (Phase 3)Study completedNCT05027802
What this trial is testing

A Rollover Study to Further Evaluate the Safety and Efficacy of Palovarotene Capsules in Male and Female Participants Aged ≥14 Years With Fibrodysplasia Ossificans Progressiva (FOP) Who Have Completed the Relevant Parent Studies.

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Ipsen 61
Early research (Phase 1)Study completedNCT04829773
What this trial is testing

Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult Subjects

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 48
Testing effectiveness (Phase 2)Study completedNCT02190747
What this trial is testing

An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 40
Large-scale testing (Phase 3)Active Not RecruitingNCT06508021
What this trial is testing

Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Ashibio Inc 92
Not applicableStudy completedNCT04665323
What this trial is testing

An International Cross-sectional Survey to Evaluate the Burden of Fibrodysplasia Ossificans Progressiva (FOP) on Patients and Their Families.

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Ipsen 411
Large-scale testing (Phase 3)WithdrawnNCT04577820
What this trial is testing

Study to Assess the Efficacy and Safety of Garetosmab in Japanese Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodyplasia Ossificans Progressiva (FOP)Heterotopic Ossification (HO)
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Ended earlyNCT05039515
What this trial is testing

Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP).

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 113
Not applicableLooking for participantsNCT02745158
What this trial is testing

The Fibrodysplasia Ossificans Progressiva (FOP) Registry

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
The International FOP Association 800
Testing effectiveness (Phase 2)Ended earlyNCT02521792
What this trial is testing

In-Home Evaluation of Episodic Administration of Palovarotene in Fibrodysplasia Ossificans Progressiva (FOP) Subjects

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 6
Not applicableStudy completedNCT02322255
What this trial is testing

A Natural History Study of Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 114
Not applicableStudy completedNCT06064656
What this trial is testing

A Non-Interventional Study of Clinical Characteristics and Mortality of US Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Regeneron Pharmaceuticals 131
Large-scale testing (Phase 3)Not Yet RecruitingNCT07559513
What this trial is testing

Investigate the Safety, Pharmacokinetics (PK), and Efficacy of Garetosmab in Children and Adolescents With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Regeneron Pharmaceuticals 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT04307953
What this trial is testing

Saracatinib Trial TO Prevent FOP

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Amsterdam UMC, location VUmc 20
Not applicableLooking for participantsNCT06724562
What this trial is testing

IL1 Inhibition in FOP

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
University of California, San Francisco 11
Testing effectiveness (Phase 2)Looking for participantsNCT05090891
What this trial is testing

To Assess the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Incyte Corporation 98
Early research (Phase 1)Study completedNCT05099445
What this trial is testing

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis

Who this might be right for
Renal ImpairmentHemodialysis
Incyte Corporation 48
Not applicableTemporarily Not AvailableNCT07301450
What this trial is testing

An Expanded Access Program of Garetosmab in Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva (FOP)
Regeneron Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT03188666
What this trial is testing

Examine the Safety, Tolerability and Effects on Abnormal Bone Formation of REGN2477 in Patients With Fibrodysplasia Ossificans Progressiva

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Regeneron Pharmaceuticals 44
Not applicableStudy completedNCT02066324
What this trial is testing

Urine Sample Collection From FOP Patients

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Novartis Pharmaceuticals 25
Testing effectiveness (Phase 2)Study completedNCT02279095
What this trial is testing

An Open-Label Extension Study of Palovarotene Treatment in Fibrodysplasia Ossificans Progressiva (FOP)

Who this might be right for
Fibrodysplasia Ossificans Progressiva
Clementia Pharmaceuticals Inc. 58
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