Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “First Line Chemotherapy”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05200481
What this trial is testing

Study of Safety and Efficacy of Brigatinib Plus Chemotherapy or Brigatinib Only in Advanced ALK-Positive Lung Cancer (MASTERPROTOCOL ALK)

Who this might be right for
Non Small Cell Lung CancerALK Gene Mutation
Intergroupe Francophone de Cancerologie Thoracique 110
Large-scale testing (Phase 3)UnknownNCT03002064
What this trial is testing

Docetaxol Plus Cisplatin Versus 5-Fu Plus Cisplatin as 1st-line Chemotherapy in Advanced ESCC Patients

Who this might be right for
Esophagus CancerChemotherapy Effects
Sun Yat-sen University 358
Testing effectiveness (Phase 2)Study completedNCT03745430
What this trial is testing

RAmucirumab Combined wIth Standard Nab-paclitaxel and Gemcitabine as First-line Chemotherapy in Patients With Advanced Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic Adenocarcinoma
Hellenic Cooperative Oncology Group 54
Not applicableEnded earlyNCT02011087
What this trial is testing

Bioelectrical Impedance Phase Angle in Predicting Treatment Outcome in Patients With Extensive Stage Small Cell Lung Cancer Receiving First-Line Chemotherapy

Who this might be right for
Extensive Stage Small Cell Lung Cancer
Wake Forest University Health Sciences 1
Large-scale testing (Phase 3)Ended earlyNCT02359162
What this trial is testing

Efficacy and Safety Study of P-Gemox vs.EPOCH as First-line Chemotherapy to Treat NK/T-cell Lymphoma With Early Stage

Who this might be right for
Lymphoma, Extranodal NK-T-Cell
Sun Yat-sen University 50
Large-scale testing (Phase 3)UnknownNCT01917279
What this trial is testing

Capecitabine Maintenance Therapy Following Capecitabine Combined With Docetaxel in Treatment of mBC

Who this might be right for
Breast NeoplasmsNeoplasms by SiteNeoplasm Metastasis+2 more
Binghe Xu 280
Large-scale testing (Phase 3)UnknownNCT03958890
What this trial is testing

A Clinical Trial Comparing HLX10 With Placebo Combined With Chemotherapy (Cisplatin + 5-fu) in the First-line Treatment of Locally Advanced/Metastatic Esophageal Squamous Cell Carcinoma (ESCC)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Shanghai Henlius Biotech 489
Large-scale testing (Phase 3)Not Yet RecruitingNCT07829549
What this trial is testing

Phase III Study of RC148 Plus Chemotherapy Versus Tislelizumab Plus Chemotherapy as First-Line Treatment for Non-Squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations

Who this might be right for
Previously Untreated Locally Advanced (IIIB/IIIC) or Metastatic (IV) e Nsq NSCLC Without Actionable Genomic Alterations
RemeGen Co., Ltd. 540
Not applicableStudy completedNCT04135521
What this trial is testing

Dose-dense Chemotherapy Versus Intraperitoneal Chemotherapy as First-line Chemotherapy in Advanced Ovarian Cancer

Who this might be right for
Advanced Ovarian Cancer
Far Eastern Memorial Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT07290010
What this trial is testing

The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
Hebei Medical University Fourth Hospital 25
Testing effectiveness (Phase 2)Looking for participantsNCT07058519
What this trial is testing

Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC

Who this might be right for
Locally Advanced or Metastatic EGFRm Non-small Cell Lung Cancer (NSCLC)
Shanghai Chest Hospital 250
Large-scale testing (Phase 3)Ended earlyNCT04163900
What this trial is testing

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
NuCana plc 773
Not applicableLooking for participantsNCT06727981
What this trial is testing

First-Line and Neoadjuvant Immunotherapy for Gastric Cancer

Who this might be right for
Advanced Gastric CancerLocally Advanced Gastric Carcinoma
Qilu Hospital of Shandong University 500
Early research (Phase 1)Ended earlyNCT05484011
What this trial is testing

A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
HiberCell, Inc. 5
Large-scale testing (Phase 3)Study completedNCT03067792
What this trial is testing

FOLFIRI Versus Docetaxel and Cisplatin as a Second-line Chemotherapy After Failure of First-line Chemotherapy in Advanced Gastric Cancer

Who this might be right for
Inoperable Gastric Cancer
Yonsei University 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06684873
What this trial is testing

A Multicenter, Single-arm, Open-label Study Evaluating the Safety and Efficacy of AK112 Combined With Chemotherapy as First-line Treatment for Non-squamous NSCLC Patients With BRAIN Metastases and Negative Driver Genes (IVO BRAIN)

Who this might be right for
NSCLCBrain Metastasases
Sun Yat-sen University 55
Testing effectiveness (Phase 2)Study completedNCT02026583
What this trial is testing

A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer Patients

Who this might be right for
Colorectal Cancer
Samsung Medical Center 43
Testing effectiveness (Phase 2)Study completedNCT02716766
What this trial is testing

Study of SECOX Versus Sorafenib as First-Line Treatment in Patients With Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Carcinoma, HepatocellularSecondary
The University of Hong Kong 46
Testing effectiveness (Phase 2)Study completedNCT00557102
What this trial is testing

Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver and/or Lung

Who this might be right for
Colorectal CancerMetastatic Cancer
National Cancer Institute, France 24
Large-scale testing (Phase 3)Study completedNCT01229813
What this trial is testing

Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.

Who this might be right for
Colorectal Cancer
Lund University Hospital 233
Next Page