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Results for “Gastroesophageal-junction Cancer (GEJ)”

211 trials

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Showing 20 of 211 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)Study completedNCT00517829
What this trial is testing

Docetaxel+Oxali+/-Cetux Met Gastric/GEJ

Who this might be right for
Gastric Cancer Adenocarcinoma Metastatic
US Oncology Research 150
Testing effectiveness (Phase 2)Study completedNCT03686488
What this trial is testing

TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction AdenocarcinomaGastric Cancer
H. Lee Moffitt Cancer Center and Research Institute 23
Large-scale testing (Phase 3)Active Not RecruitingNCT05002127
What this trial is testing

Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaGastric Adenocarcinoma
ALX Oncology Inc. 127
Early research (Phase 1)WithdrawnNCT05296005
What this trial is testing

Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers

Who this might be right for
Clinical Stage I Gastric Cancer AJCC v8Clinical Stage II Gastric Cancer AJCC v8Clinical Stage IIA Gastric Cancer AJCC v8+22 more
Ohio State University Comprehensive Cancer Center
Early research (Phase 1)Active Not RecruitingNCT05539430
What this trial is testing

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Who this might be right for
Gastric CancerGastroesophageal-junction CancerEsophageal Cancer+1 more
Legend Biotech USA Inc 56
Testing effectiveness (Phase 2)Looking for participantsNCT06121700
What this trial is testing

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer

Who this might be right for
AdenocarcinomaStomach NeoplasmGastroesophageal-junction Cancer+6 more
Fudan University 55
Large-scale testing (Phase 3)Active Not RecruitingNCT04704934
What this trial is testing

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

Who this might be right for
Gastric Cancer, AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Daiichi Sankyo 490
Testing effectiveness (Phase 2)Ended earlyNCT05311176
What this trial is testing

IMU-131 (HER-Vaxx) in Combination With Chemotherapy or Pembrolizumab in Patients With Metastatic HER2/Neu Over-Expressing Gastric Cancer (nextHERIZON)

Who this might be right for
Gastric CancerCancer of StomachGastric Adenocarcinoma+3 more
Imugene Limited 7
Testing effectiveness (Phase 2)Looking for participantsNCT04592211
What this trial is testing

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer

Who this might be right for
Gastric Cancer Stage IV
Yonsei University 71
Testing effectiveness (Phase 2)Study completedNCT01498289
What this trial is testing

S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal CancerGastric Cancer
SWOG Cancer Research Network 213
Not applicableUnknownNCT04443036
What this trial is testing

Clinical Study of Nab-paclitaxel Combined With Toripalimab in Local Advanced or Metastatic G/GEJ Carcinoma

Who this might be right for
Gastric Carcinoma
China Medical University, China 44
Not applicableLooking for participantsNCT06605404
What this trial is testing

Pan-tumor MRD Study

Who this might be right for
Muscle Invasive Bladder Urothelial CarcinomaEsophageal CancerGastric and Gastroesophageal Junction (GEJ) Adenocarcinoma+4 more
Paradigm Health 1,350
Early research (Phase 1)Looking for participantsNCT07660055
What this trial is testing

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

Who this might be right for
Breast CancerNon-small Cell Lung Cancer (NSCLC)Gastric/Gastroesophageal Junction (GEJ) Cancer+1 more
Novartis Pharmaceuticals 156
Testing effectiveness (Phase 2)Ended earlyNCT00848783
What this trial is testing

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Who this might be right for
Gastric CancerGastric AdenocarcinomaEsophageal Cancer
NYU Langone Health 8
Testing effectiveness (Phase 2)Study completedNCT03852251
What this trial is testing

AK104, a PD-1/CTLA-4 Bispecific Antibody, for Advanced Solid Tumors or With mXELOX/XELOX as First-line Therapy for Advanced Gastric or GEJ Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaAdvanced Solid TumorsGastroesophageal Junction Adenocarcinoma
Akeso 338
Not applicableStudy completedNCT05892926
What this trial is testing

HER2-positive Locally Advanced/Metastatic Gastric and/or Gastroesophageal Junction (GEJ) Adenocarcinoma in Russia

Who this might be right for
Adenocarcinoma
AstraZeneca 204
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06942767
What this trial is testing

Combination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Qilu Pharmaceutical Co., Ltd. 100
Early research (Phase 1)Not Yet RecruitingNCT07333820
What this trial is testing

Clinical Study to Evaluate the Safety and Anti-Tumor Activity of AB-201

Who this might be right for
Malignant Neoplasm of Stomach, Unspecified
Yonsei University 18
Large-scale testing (Phase 3)Active Not RecruitingNCT03653507
What this trial is testing

Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW).

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.
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