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Results for “Gene Therapy”

1,996 trials

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Active, Not Recruiting
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Enrolling by Invitation

Showing 20 of 1,996 results

Early research (Phase 1)Study completedNCT03409627
What this trial is testing

Novel INXN-4001 Triple Effector Plasmid in Heart Failure

Who this might be right for
Heart FailureCardiovascular DiseasesHeart-Assist Device
Triple-Gene, LLC 12
Post-approval studies (Phase 4)WithdrawnNCT02558361
What this trial is testing

Treatment With Apremilast in Patients With Psoriatic Arthritis

Who this might be right for
Psoriatic Arthritis
University of South Florida
Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Early research (Phase 1)Ended earlyNCT00058773
What this trial is testing

Giving Gene Marked EBV Specific T-Cells to Patients Receiving a BMT for Relapsed EBV-Positive Hodgkin Disease

Who this might be right for
Hodgkin DiseaseNon-Hodgkins Lymphoma
Baylor College of Medicine 5
Early research (Phase 1)Study completedNCT03562494
What this trial is testing

VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1)

Who this might be right for
Parkinson's Disease
Neurocrine Biosciences 14
Early research (Phase 1)Looking for participantsNCT06484556
What this trial is testing

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Who this might be right for
Tumor, Solid
Tao Zhang 9
Not applicableNot Yet RecruitingNCT06694129
What this trial is testing

Real-world Observational Study of Targeted Therapy in Patients With Advanced ROS1-positive NSCLC

Who this might be right for
Non-Small Cell Lung CancerROS1 Gene RearrangementResistance+1 more
National Cancer Center, China 40
Not applicableActive Not RecruitingNCT05145062
What this trial is testing

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Who this might be right for
Blood and Lymphatic Diseases
Sangamo Therapeutics 8
Not applicableStudy completedNCT04312672
What this trial is testing

Long-term Follow-up Gene Therapy Study for RPGR- XLRP

Who this might be right for
X-Linked Retinitis Pigmentosa
Janssen Research & Development, LLC 42
Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Testing effectiveness (Phase 2)Active Not RecruitingNCT04395677
What this trial is testing

AB-106 in Subjects With Advanced NSCLC Harboring ROS1 Fusion Gene

Who this might be right for
Non Small Cell Lung Cancer
Nuvation Bio Inc. 173
Early research (Phase 1)Study completedNCT00004806
What this trial is testing

Phase I Study of Liposome-Mediated Gene Transfer in Patients With Cystic Fibrosis

Who this might be right for
Cystic Fibrosis
University of Alabama at Birmingham 9
Testing effectiveness (Phase 2)Ended earlyNCT04273269
What this trial is testing

A Safety and Efficacy Study of LYS-GM101 Gene Therapy in Patients With GM1 Gangliosidosis

Who this might be right for
GM1 Gangliosidosis
LYSOGENE 5
Early research (Phase 1)Active Not RecruitingNCT05238922
What this trial is testing

Study of INCB123667 in Subjects With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Incyte Corporation 291
Testing effectiveness (Phase 2)UnknownNCT01131429
What this trial is testing

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Who this might be right for
Neoplasms, LungCarcinoma, Non-Small Cell LungDrug Therapy+1 more
Chinese PLA General Hospital 60
Not applicableLooking for participantsNCT07737756
What this trial is testing

A Real-World Medical Chart Review of Spinal Muscular Atrophy Patients Treated With Onasemnogene Abeparvovec in Saudi Arabia

Who this might be right for
Spinal Muscular Atrophy
Novartis Pharmaceuticals 6
Testing effectiveness (Phase 2)Study completedNCT02576795
What this trial is testing

Gene Therapy Study in Severe Haemophilia A Patients (270-201)

Who this might be right for
Severe Haemophilia A
BioMarin Pharmaceutical 15
Testing effectiveness (Phase 2)Study completedNCT01734850
What this trial is testing

Safety Study of a Dual Anti-HIV Gene Transfer Construct to Treat HIV-1 Infection

Who this might be right for
Human Immunodeficiency Virus
Calimmune, Inc. 13
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07775313
What this trial is testing

Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIM

Who this might be right for
WHIMWartsHypogammaglobulinemia+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT05228145
What this trial is testing

Gene Therapy Study for Children With CLN5 Batten Disease

Who this might be right for
Neuronal Ceroid Lipofuscinosis CLN5
Neurogene Inc. 6
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