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Results for “Gene Therapy”

1,897 trials

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Showing 20 of 1,897 results

Not applicableLooking for participantsNCT06643000
What this trial is testing

Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal MetastasisEGFR Gene Mutation
Henan Cancer Hospital 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04408625
What this trial is testing

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Who this might be right for
Frontotemporal Dementia
Prevail Therapeutics 35
Not applicableLooking for participantsNCT06237790
What this trial is testing

A Comparative Analysis of Speech Perception Between Cochlear Implant Patients and DFNB9 Patients Receiving Gene Therapy

Who this might be right for
Hearing LossGenetic DiseaseSpeech Perception
Eye & ENT Hospital of Fudan University 180
Early research (Phase 1)Looking for participantsNCT06539338
What this trial is testing

Investigate Safety of INT2104 Infusions in Participants Aged 18 Years of Age and Older Who Have B-cell Cancers That Came Back After Previous Treatment

Who this might be right for
Lymphomas Non-Hodgkin's B-CellPrecursor Cell Lymphoblastic Leukemia-Lymphoma
Kite, A Gilead Company 34
Not applicableLooking for participantsNCT06887348
What this trial is testing

Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

Who this might be right for
MelanomaMetastatic MelanomaAdvanced Solid Tumor+1 more
Replimune Inc. 50
Very early researchLooking for participantsNCT06207552
What this trial is testing

Evaluation of the Safety, Tolerability and Efficacy of a Gene Therapy Drug for the Treatment of Pediatric Fabry Disease

Who this might be right for
Fabry Disease
Children's Hospital of Fudan University 6
Not applicableNot Yet RecruitingNCT06825845
What this trial is testing

Long Term Follow-up Observational Study in Patients Treated with Gene-Modified T-Cell Therapy

Who this might be right for
Relapsed or Refractory Multiple Myeloma
CARsgen Therapeutics Co., Ltd. 1,500
Testing effectiveness (Phase 2)Study completedNCT02280811
What this trial is testing

T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers

Who this might be right for
Vaginal CancerCervical CancerAnal Cancer+2 more
National Cancer Institute (NCI) 12
Not applicableStudy completedNCT03894852
What this trial is testing

SRSF2 Gene Mutation in Patients With t-MDS/AML

Who this might be right for
Therapy Related Myelodysplastic Syndrome and Therapy Related Acute Myeloid Leukemia
Zeinab Albadry Mohammed Zahran 139
Not applicableStudy completedNCT03512847
What this trial is testing

Predictive Gene Profiles and Dynamic Measurement of Treatment Response in Metastatic Non-small Cell Lung Cancer

Who this might be right for
Metastatic Nonsmall Cell Lung Cancer
Zealand University Hospital 150
Not applicableActive Not RecruitingNCT03275051
What this trial is testing

Long-term Follow-up of Subjects Treated With OTL-300 for Transfusion Dependent Beta-thalassemia Study (TIGET-BTHAL)

Who this might be right for
Beta Thalassaemia
IRCCS San Raffaele 9
Not applicableWithdrawnNCT02006849
What this trial is testing

ACTH Treatment of APOL1- Associated Nephropathy

Who this might be right for
Kidney Disease
Wake Forest University Health Sciences
Testing effectiveness (Phase 2)Study completedNCT01058785
What this trial is testing

Phase II Study of Lucanix™ in Patients With Stages II-IV Non-Small Cell Lung Cancer

Who this might be right for
Lung NeoplasmCarcinoma, Bronchogenic
NovaRx Corporation 75
Large-scale testing (Phase 3)Study completedNCT03505099
What this trial is testing

Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2

Who this might be right for
Spinal Muscular Atrophy
Novartis Gene Therapies 30
Testing effectiveness (Phase 2)Ended earlyNCT02953093
What this trial is testing

Study of Acarbose in Longevity

Who this might be right for
Aging
Montefiore Medical Center 28
Large-scale testing (Phase 3)Study completedNCT02752035
What this trial is testing

ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Astellas Pharma Global Development, Inc. 183
Large-scale testing (Phase 3)Study completedNCT03837184
What this trial is testing

Single-Dose Gene Replacement Therapy Using for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies

Who this might be right for
Spinal Muscular Atrophy Type I
Novartis Gene Therapies 2
Not applicableUnknownNCT00910884
What this trial is testing

Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission.

Who this might be right for
Breast Cancer
Brabant Research 300
Testing effectiveness (Phase 2)Looking for participantsNCT06109558
What this trial is testing

The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC

Who this might be right for
Non Small Cell Lung CancerRET Gene MutationMET Amplification+1 more
Hunan Province Tumor Hospital 120
Not applicableLooking for participantsNCT07012382
What this trial is testing

Single Gene Polymorphism and the Success Rate of Inferior Alveolar Nerve Block

Who this might be right for
Pulpitis - Irreversible
Jamia Millia Islamia 200
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