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Results for “Generalized Lipodystrophy”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Study completedNCT03514420
What this trial is testing

Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Partial Lipodystrophy (FPL)

Who this might be right for
Familial Partial Lipodystrophy
Akcea Therapeutics 4
Not applicableLooking for participantsNCT02325674
What this trial is testing

MEASuRE: Metreleptin Effectiveness And Safety Registry

Who this might be right for
Generalised LipodystrophyPartial Lipodystrophy
Chiesi Farmaceutici S.p.A. 100
Not applicableLooking for participantsNCT03553420
What this trial is testing

Registry for Patients With Lipodystrophy

Who this might be right for
Lipodystrophy AcquiredLipodystrophy Congenital
University of Ulm 5,000
Not applicableActive Not RecruitingNCT03936829
What this trial is testing

Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes

Who this might be right for
Lipodystrophy AcquiredType1diabetes
Children's Hospital of Fudan University 10
Not applicableStudy completedNCT02577952
What this trial is testing

Lipodystrophy Connect Patient Registry

Who this might be right for
Lipodystrophy
PatientCrossroads 257
Testing effectiveness (Phase 2)Study completedNCT04159415
What this trial is testing

Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 16
Not applicableAvailableNCT04710056
What this trial is testing

Expanded Access to REGN4461 for Patients With Diseases Associated With Deficient Leptin Signaling

Who this might be right for
LipodystrophyGeneralized Lipodystrophy (GLD)Monogenic Obesity (MOB)
Regeneron Pharmaceuticals
Not applicableLooking for participantsNCT06755775
What this trial is testing

PET Imaging Targeting Granzyme B Predicts Immunotherapy Efficacy in Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Ruijin Hospital 150
Large-scale testing (Phase 3)Study completedNCT00896298
What this trial is testing

Trial of Leptin Replacement Therapy in Patients With Lipodystrophy

Who this might be right for
HypoleptinemiaGeneralized LipodystrophyPartial Lipodystrophy+1 more
University of Texas Southwestern Medical Center 25
Testing effectiveness (Phase 2)Ended earlyNCT03848182
What this trial is testing

Analyzing Childhood Recall Antigens in Patients With Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Albert Einstein College of Medicine 10
Not applicableNot Yet RecruitingNCT06863441
What this trial is testing

The Value of PET Imaging Targeting Granzyme B in Predicting Efficacy and Prognosis in T-NK Cell Lymphoma

Who this might be right for
T-NK Cell Lymphoma
Ruijin Hospital 50
Not applicableNot Yet RecruitingNCT07799012
What this trial is testing

Sexual Quality of Life in Female Patients With Lipodystrophy Syndromes or Turner's Syndrome: a Case-control Study

Who this might be right for
Lipodystrophy Congenital GeneralizedLipodystrophy, Familial PartialTurner Syndrome
Assistance Publique - Hôpitaux de Paris 1,416
Not applicableNot Yet RecruitingNCT06916442
What this trial is testing

Granzyme B-targeted PET Imaging Monitoring Tumor Responses to Immunotherapy

Who this might be right for
PET/CTSolid Tumors, AdultSolid Tumors, Advanced Solid Tumors
Zhongnan Hospital 200
Large-scale testing (Phase 3)Looking for participantsNCT07220785
What this trial is testing

Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 28
Testing effectiveness (Phase 2)Looking for participantsNCT05888532
What this trial is testing

64Cu-GRIP B in Patients With Advanced Malignancies

Who this might be right for
Prostate CancerRenal CancerUrethral Cancer+3 more
Rahul Aggarwal 91
Not applicableLooking for participantsNCT04808596
What this trial is testing

Pulmonary Hypertension Biorepository and Registry

Who this might be right for
Pulmonary HypertensionPulmonary Arterial HypertensionPulmonary Hypertension Due to Left Heart Disease+6 more
University of Kansas Medical Center 300
Not applicableUnknownNCT00345280
What this trial is testing

Ocular Surface Changes in Patients With Cystic Fibrosis

Who this might be right for
Eye Manifestations
University of Bialystok 26
Post-approval studies (Phase 4)Study completedNCT04026178
What this trial is testing

Immunogenicity of Metreleptin in Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Aegerion Pharmaceuticals, Inc. 11
Not applicableLooking for participantsNCT06725940
What this trial is testing

GzmB-PET/CT to Evaluate Neoadjuvant Therapy Efficacy in Breast Cancer

Who this might be right for
Breast Cancer Invasive
Shanghai Jiao Tong University School of Medicine 50
Large-scale testing (Phase 3)Study completedNCT06548100
What this trial is testing

The Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 9
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