Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Generalized Lipodystrophy”

27 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 27 results

Not applicableActive Not RecruitingNCT03936829
What this trial is testing

Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes

Who this might be right for
Lipodystrophy AcquiredType1diabetes
Children's Hospital of Fudan University 10
Not applicableLooking for participantsNCT03553420
What this trial is testing

Registry for Patients With Lipodystrophy

Who this might be right for
Lipodystrophy AcquiredLipodystrophy Congenital
University of Ulm 5,000
Not applicableNot Yet RecruitingNCT06863441
What this trial is testing

The Value of PET Imaging Targeting Granzyme B in Predicting Efficacy and Prognosis in T-NK Cell Lymphoma

Who this might be right for
T-NK Cell Lymphoma
Ruijin Hospital 50
Large-scale testing (Phase 3)Study completedNCT00896298
What this trial is testing

Trial of Leptin Replacement Therapy in Patients With Lipodystrophy

Who this might be right for
HypoleptinemiaGeneralized LipodystrophyPartial Lipodystrophy+1 more
University of Texas Southwestern Medical Center 25
Large-scale testing (Phase 3)Active Not RecruitingNCT02262832
What this trial is testing

Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy

Who this might be right for
LipodystrophyDiabetesHyperlipidemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 24
Testing effectiveness (Phase 2)Study completedNCT05000372
What this trial is testing

68Ga-grazytracer PET/CT of Tumor Responses to Immunotherapy

Who this might be right for
Cancer
Peking University Cancer Hospital & Institute 24
Not applicableUnknownNCT00345280
What this trial is testing

Ocular Surface Changes in Patients With Cystic Fibrosis

Who this might be right for
Eye Manifestations
University of Bialystok 26
Not applicableLooking for participantsNCT06755775
What this trial is testing

PET Imaging Targeting Granzyme B Predicts Immunotherapy Efficacy in Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Ruijin Hospital 150
Not applicableLooking for participantsNCT02325674
What this trial is testing

MEASuRE: Metreleptin Effectiveness And Safety Registry

Who this might be right for
Generalised LipodystrophyPartial Lipodystrophy
Amryt Pharma 100
Large-scale testing (Phase 3)Active Not RecruitingNCT06548100
What this trial is testing

The Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 9
Not applicableLooking for participantsNCT04808596
What this trial is testing

Pulmonary Hypertension Biorepository and Registry

Who this might be right for
Pulmonary HypertensionPulmonary Arterial HypertensionPulmonary Hypertension Due to Left Heart Disease+6 more
University of Kansas Medical Center 300
Post-approval studies (Phase 4)Study completedNCT03344159
What this trial is testing

Spironolactone Therapy in Chronic Stable Right HF Trial

Who this might be right for
Chronic Right-Sided Heart FailurePulmonary Arterial HypertensionPulmonary Hypertension, Primary, 2+3 more
Ottawa Heart Institute Research Corporation 15
Not applicableAvailableNCT04710056
What this trial is testing

Expanded Access to REGN4461 for Patients With Diseases Associated With Deficient Leptin Signaling

Who this might be right for
LipodystrophyGeneralized Lipodystrophy (GLD)Monogenic Obesity (MOB)
Regeneron Pharmaceuticals
Large-scale testing (Phase 3)Looking for participantsNCT06502990
What this trial is testing

Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Amryt Pharma 15
Not applicableStudy completedNCT06982053
What this trial is testing

[68Ga]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant Therapy

Who this might be right for
Colorectal Cancer Control and PreventionColorectal Cancer RecurrentColorectal Cancer Metastatic+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 21
Testing effectiveness (Phase 2)Study completedNCT04159415
What this trial is testing

Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 16
Post-approval studies (Phase 4)Study completedNCT04026178
What this trial is testing

Immunogenicity of Metreleptin in Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Aegerion Pharmaceuticals, Inc. 11
Testing effectiveness (Phase 2)Looking for participantsNCT05888532
What this trial is testing

64Cu-GRIP B in Patients With Advanced Malignancies

Who this might be right for
Prostate CancerRenal CancerUrethral Cancer+3 more
Rahul Aggarwal 91
Large-scale testing (Phase 3)Looking for participantsNCT07220785
What this trial is testing

Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 28
Not applicableStudy completedNCT02577952
What this trial is testing

Lipodystrophy Connect Patient Registry

Who this might be right for
Lipodystrophy
PatientCrossroads 257
Load More Results