Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Genetic Mutations”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07414290
What this trial is testing

A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R08b in Parkinson's Disease Patients With GBA1 Mutations

Who this might be right for
Parkinson Disease (PD)
Shanghai Vitalgen BioPharma Co., Ltd. 17
Not applicableApproved For MarketingNCT04058210
What this trial is testing

VX-445/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients Heterozygous for F508del Mutation and a Minimal Function Mutation (F/MF Genotypes)

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07743268
What this trial is testing

Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)
n-Lorem Foundation 6
Testing effectiveness (Phase 2)UnknownNCT00299897
What this trial is testing

SP01A: The Study of an Oral Entry Inhibitor in Treatment-Experienced HIV Patients

Who this might be right for
HIV InfectionsHuman Immunodeficiency Virus
Samaritan Pharmaceuticals, Inc 60
Early research (Phase 1)UnknownNCT03645200
What this trial is testing

Treatment of Carrying TP53 Harmful Mutations

Who this might be right for
Advanced Cancer
Tianjin Medical University Second Hospital 60
Early research (Phase 1)Study completedNCT01225536
What this trial is testing

Dose Escalation Study of ARQ 736 in Adult Subjects With Advanced Solid Tumors Harboring BRAF and/or NRAS Mutations

Who this might be right for
Solid Tumor
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 24
Testing effectiveness (Phase 2)Study completedNCT00588445
What this trial is testing

Phase II Trial to Correlate Radiographic Response Induced By Gefitinib With Mutations in the Protein-Tyrosine Kinase Domain of the EGF Receptor Gene

Who this might be right for
Lung CancerNon-small Cell Lung CancerBronchioloalveolar Cancer
Memorial Sloan Kettering Cancer Center 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439175
What this trial is testing

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Looking for participantsNCT07505173
What this trial is testing

Hippocampus-Protective Radiotherapy Combined With Osimertinib for Symptomatic Brain Metastases in EGFR-Mutated Lung Cancer

Who this might be right for
Naive Advanced Non-small Cell Lung Cancer With EGFR-sensitive Mutations (EGFR Exon 19 Deletion and Exon 21 L858R Mutation) and Symptomatic Brain Metastases
Tianjin Medical University Cancer Institute and Hospital 74
Not applicableStudy completedNCT04236102
What this trial is testing

KEBI-Cyto Study - Use of the Biocartis Idylla

Who this might be right for
Pancreatic AdenocarcinomaLung Cancer
Royal Cornwall Hospitals Trust 55
Not applicableStudy completedNCT06594367
What this trial is testing

A Possible Founding PKD2 Mutation Associated With Variable Phenotypes of ADPKD in Bergamo Province

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Mario Negri Institute for Pharmacological Research 10
Large-scale testing (Phase 3)Study completedNCT04058353
What this trial is testing

VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 271
Not applicableEnded earlyNCT01103128
What this trial is testing

Validation of a Mouse Model of Pancreatic Carcinogenesis

Who this might be right for
Pancreatic Cancer
Columbia University 450
Not applicableUnknownNCT02114554
What this trial is testing

Mitochondrial nt3243 A>G Mutation in Taiwan

Who this might be right for
MELAS SyndromeNoninsulin-dependent Diabetes Mellitus With Deafness
National Taiwan University Hospital 40
Not applicableUnknownNCT01838577
What this trial is testing

Genetics of EGFR (Epidermal Growth Factor Receptor) Mutation Study

Who this might be right for
EGFR Mutation Positive Non Small Cell Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC 2,000
Testing effectiveness (Phase 2)Study completedNCT01898312
What this trial is testing

BRCA1/2 and Effect of Mifepristone on the Breast

Who this might be right for
Women With Mutations in the Breast Cancer Susceptibility Genes BRCA1,2
Karolinska Institutet 45
Not applicableStudy completedNCT03802812
What this trial is testing

Thin Bronchoscope and Virtual Bronchoscopic Navigation System for Tuberculosis

Who this might be right for
Tuberculosis
Pusan National University Hospital 88
Not applicableStudy completedNCT01783795
What this trial is testing

Dent Disease Mutation Genotyping

Who this might be right for
Dent Disease
Mayo Clinic 180
Large-scale testing (Phase 3)Study completedNCT01897233
What this trial is testing

Study of Lumacaftor in Combination With Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 62
Not applicableUnknownNCT05411276
What this trial is testing

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

Who this might be right for
HER2 Mutant Non-small Cell Lung Cancer
Beijing Chest Hospital 15
Next Page