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Results for “Genomic Alterations”

80 trials

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Showing 20 of 80 results

Testing effectiveness (Phase 2)Study completedNCT04632992
What this trial is testing

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response

Who this might be right for
Advanced Unresectable or Metastatic Solid Malignancy
Genentech, Inc. 252
Testing effectiveness (Phase 2)Active Not RecruitingNCT05186974
What this trial is testing

Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer
Gilead Sciences 193
Testing effectiveness (Phase 2)WithdrawnNCT01814865
What this trial is testing

Anti-Proliferative Effects and Genomic Alterations of Abiraterone Acetate Compared to an Aromatase Inhibitor in Post-menopausal HR+ Operable Breast Cancer

Who this might be right for
Post-menopausal ER+ Stage I-IIIA Primary Operable Breast Cancer
British Columbia Cancer Agency
Not applicableStudy completedNCT03116633
What this trial is testing

Concordance of Inivata Liquid Biopsy With Standard Tissue Biopsy

Who this might be right for
Non-Small Cell Lung Cancer
Inivata 34
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07393555
What this trial is testing

Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial)

Who this might be right for
Recurrent Lung Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8
SWOG Cancer Research Network 117
Not applicableLooking for participantsNCT02534649
What this trial is testing

Bergonie Institut Profiling : Fighting Cancer by Matching Molecular Alterations and Drugs in Early Phase Trials

Who this might be right for
Solid TumorHematological Malignancy
Institut Bergonié 10,000
Not applicableWithdrawnNCT06133790
What this trial is testing

Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers

Who this might be right for
Head and Neck Cancer
GCS Ramsay Santé pour l'Enseignement et la Recherche
Large-scale testing (Phase 3)Active Not RecruitingNCT05943795
What this trial is testing

A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma

Who this might be right for
Non-small Cell Lung AdenocarcinomaSquamous Cell Carcinoma of Lung
Sichuan Baili Pharmaceutical Co., Ltd. 589
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Not applicableLooking for participantsNCT02146170
What this trial is testing

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerExtrapulmonary Small Cell Cancer+2 more
National Cancer Institute (NCI) 2,000
Not applicableStudy completedNCT02620527
What this trial is testing

Concordance Between ctDNA Assay and FoundationOne

Who this might be right for
Circulating Tumor DNACancerNeoplasms+2 more
Foundation Medicine 1,400
Not applicableStudy completedNCT00836732
What this trial is testing

Mesenchymal Stem Cells: Alterations in Genome

Who this might be right for
Pened Chest Surgery for Programmes Coronary Bypass
Nantes University Hospital 35
Large-scale testing (Phase 3)Looking for participantsNCT05770037
What this trial is testing

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+8 more
Cancer Research UK 30
Not applicableEnded earlyNCT02762877
What this trial is testing

Concordance of Key Actionable Genomic Alterations as Assessed in Tumor Tissue and Plasma in Non Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Carcinoma
Genomic Health®, Inc. 140
Large-scale testing (Phase 3)Active Not RecruitingNCT06074588
What this trial is testing

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC 556
Not applicableStudy completedNCT04781569
What this trial is testing

Staphylococcus Aureus Caught in Action at the Site of Infection

Who this might be right for
Staphylococcus (S.) Aureus Infection
University Hospital, Basel, Switzerland 100
Not applicableStudy completedNCT03457779
What this trial is testing

Pilot Study To Investigate Targetable Metabolic Pathways Sustaining Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast Cancer
Baylor Research Institute 16
Not applicableEnded earlyNCT04412070
What this trial is testing

Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

Who this might be right for
Bladder Cancer
Hopital Foch 20
Large-scale testing (Phase 3)Looking for participantsNCT05770102
What this trial is testing

DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition

Who this might be right for
MalignancyMalignant NeoplasmLymphoproliferative Disorders+7 more
Cancer Research UK 30
Large-scale testing (Phase 3)Looking for participantsNCT05786716
What this trial is testing

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

Who this might be right for
Haematological MalignancyColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK 30
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