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Results for “Germline Mutation Abnormality”

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Showing 20 of 0 results

Not applicableLooking for participantsNCT07292246
What this trial is testing

A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study)

Who this might be right for
Breast CancerBRCA 1 Gene MutationBRCA 2 Gene Mutation+5 more
Vasileios Kalles 15
Testing effectiveness (Phase 2)UnknownNCT02681562
What this trial is testing

Olaparib in Locally Advanced ER, PgR and HER2 Negative (Triple Negative) and in Locally Advanced Germline BRCA Mutation-positive Breast Cancer Patients

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Istituti Ospitalieri di Cremona 45
Not applicableUnknownNCT04516083
What this trial is testing

Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation

Who this might be right for
Cancer Gene MutationLynch SyndromeEndometrial Cancer+1 more
RWJ Barnabas Health at Jersey City Medical Center 100
Not applicableStudy completedNCT02963688
What this trial is testing

BRCA 1/2 Mutation in Korean Patients With Epithelial Ovarian Cancer

Who this might be right for
To Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
Samsung Medical Center 298
Not applicableActive Not RecruitingNCT03857594
What this trial is testing

Integrative Sequencing In Germline and Hereditary Tumours

Who this might be right for
Hereditary Cancer SyndromeHigh-RiskMutation+1 more
University Health Network, Toronto 10
Testing effectiveness (Phase 2)Study completedNCT01967576
What this trial is testing

Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma

Who this might be right for
PheochromocytomaParaganglioma
National Cancer Institute (NCI) 14
Not applicableLooking for participantsNCT05769517
What this trial is testing

Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries

Who this might be right for
BRCA MutationOvarian CancerUltrasound Therapy; Complications
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 6,465
Testing effectiveness (Phase 2)WithdrawnNCT06080165
What this trial is testing

Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

Who this might be right for
PTEN Gene MutationPTEN Hamartoma Tumor SyndromePTEN Hamartoma Syndrome
Stanford University
Large-scale testing (Phase 3)Study completedNCT02000622
What this trial is testing

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.

Who this might be right for
Breast Cancer MetastaticBRCA 1 Gene MutationBRCA 2 Gene Mutation
AstraZeneca 302
Not applicableUnknownNCT04368442
What this trial is testing

Cohort Study of Patients With HER2-negative MBC and BRCA 1/2 Pathogenic Mutation

Who this might be right for
Breast Cancer Metastatic
Samsung Medical Center 583
Testing effectiveness (Phase 2)Looking for participantsNCT05806515
What this trial is testing

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

Who this might be right for
Prostate AdenocarcinomaStage IIIB Prostate Cancer AJCC v8Stage IIIC Prostate Cancer AJCC v8
SWOG Cancer Research Network 44
Testing effectiveness (Phase 2)Ended earlyNCT02326844
What this trial is testing

BMN 673 (Talazoparib), an Oral PARP Inhibitor, in People With Deleterious BRCA1/2 Mutation-Associated Ovarian Cancer Who Have Had Prior PARP Inhibitor Treatment

Who this might be right for
Ovarian Cancer
National Cancer Institute (NCI) 3
Testing effectiveness (Phase 2)Study completedNCT02042378
What this trial is testing

Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation

Who this might be right for
Pancreatic CancerPancreatic Ductal Adenocarcinoma
pharmaand GmbH 19
Not applicableStudy completedNCT02821780
What this trial is testing

CADASIL Disease Discovery

Who this might be right for
Germline Mutation in the NOTCH 3 GeneCardiovascular DiseaseArterial Stiffness+2 more
National Heart, Lung, and Blood Institute (NHLBI) 20
Testing effectiveness (Phase 2)Study completedNCT01472783
What this trial is testing

Veliparib Monotherapy for Relapsed Ovarian Cancer With BRCA Mutation

Who this might be right for
Recurrent, Epithelial Ovarian Cancer
Vejle Hospital 49
Not applicableLooking for participantsNCT07419893
What this trial is testing

Germline Genetic Testing of the TP53 Gene

Who this might be right for
TP53 Gene MutationMulti-Gene Transcriptional ProfilingTP53 Gene Germline Mutation Carrier
European Institute of Oncology 1,940
Not applicableActive Not RecruitingNCT01754025
What this trial is testing

INHERIT EGFR - Studying Germline EGFR Mutations

Who this might be right for
Lung Cancer
Dana-Farber Cancer Institute 121
Not applicableLooking for participantsNCT04995198
What this trial is testing

PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

Who this might be right for
Prostate Cancer
Prostate Cancer Clinical Trials Consortium 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT03989089
What this trial is testing

Study of Pembrolizumab in Metastatic HER2-negative Breast Cancer Patients With APOBEC3B Mutation

Who this might be right for
HER2-Negative Breast Cancer
University of Malaya 44
Not applicableStudy completedNCT03030404
What this trial is testing

Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Who this might be right for
Stomach NeoplasmsStomach CancerGastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)+2 more
National Cancer Institute (NCI) 733
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