Large-scale testing (Phase 3)Active Not RecruitingNCT05417789What this trial is testingStudy of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)Who this might be right forTGCT SynOx Therapeutics Limited 128
Not applicableStudy completedNCT04952896What this trial is testingClinical Study of Magnetic Resonance Imaging and Deep Learning of Joint Synovial DiseaseWho this might be right forSynovial DiseasesPigmented Villonodular SynovitisGout+1 more Peking University Third Hospital 350
Large-scale testing (Phase 3)Active Not RecruitingNCT04488822What this trial is testingThe Efficacy and Safety of Pexidartinib in Adult Subjects With TGCTWho this might be right forTenosynovial Giant Cell Tumor Daiichi Sankyo Co., Ltd. 40
Testing effectiveness (Phase 2)Ended earlyNCT04938180What this trial is testingIntravenous AMB-05X in Tenosynovial Giant Cell Tumor PatientsWho this might be right forTenosynovial Giant Cell TumorPigmented Villonodular SynovitisTGCT+1 more AmMax Bio, Inc. 4
Early research (Phase 1)Looking for participantsNCT04192344What this trial is testingAssess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid TumorWho this might be right forNeoplasmsTenosynovial Giant Cell Tumor Abbisko Therapeutics Co, Ltd 276
Testing effectiveness (Phase 2)Study completedNCT01643850What this trial is testingMCS110 in Patients With Pigmented Villonodular Synovitis (PVNS)Who this might be right forPigmented Villonodular SynovitisPVNSGiant Cell Tumor of the Tendon Sheath+3 more Novartis Pharmaceuticals 36
Post-approval studies (Phase 4)Looking for participantsNCT07315841What this trial is testingAccuracy of Indocyanine Green (ICG) Fluorescence Imaging in Tenosynovial Giant Cell Tumor SurgeryWho this might be right forTenosynovial Giant Cell Tumor Shanghai Jiao Tong University Affiliated Sixth People's Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT07499362What this trial is testingStudy of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER)Who this might be right forTenosynovial Giant Cell Tumor Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 20
Not applicableLooking for participantsNCT07075471What this trial is testingTenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With VimseltinibWho this might be right forTenosynovial Giant Cell Tumor Deciphera Pharmaceuticals, LLC 100
Testing effectiveness (Phase 2)Study completedNCT04731675What this trial is testingAn Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the KneeWho this might be right forTenosynovial Giant Cell TumorPigmented Villonodular Synovitis (PVNS) AmMax Bio, Inc. 11
Not applicableNot Yet RecruitingNCT07503821What this trial is testingSynovial Tissue as a Biomarker in the Management of Pigmented Villonodular SynovitisWho this might be right forSynovitis Villonodular Nantes University Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT03069469What this trial is testingStudy of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell TumorWho this might be right forAdvanced Malignant NeoplasmPigmented Villonodular SynovitisGiant Cell Tumor of Tendon Sheath+2 more Deciphera Pharmaceuticals, LLC 120
Testing effectiveness (Phase 2)Study completedNCT05349643What this trial is testingEvaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCTWho this might be right forPigmented Villonodular SynovitisTGCTTenosynovial Giant Cell Tumor AmMax Bio, Inc. 20
Large-scale testing (Phase 3)Active Not RecruitingNCT05059262What this trial is testingStudy of Vimseltinib for Tenosynovial Giant Cell TumorWho this might be right forTenosynovial Giant Cell TumorPigmented Villonodular SynovitisGiant Cell Tumor of Tendon Sheath+2 more Deciphera Pharmaceuticals, LLC 123
Early research (Phase 1)Study completedNCT03291288What this trial is testingEffect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics)Who this might be right forDrug Interaction Potential Daiichi Sankyo 32
Very early researchStudy completedNCT04223635What this trial is testingStudy of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy ParticipantsWho this might be right forModerate Hepatic Impairment Daiichi Sankyo 16
Early research (Phase 1)UnknownNCT05212896What this trial is testingAn Exploratory Clinical Study of BC006 in Patients With Advanced Solid TumorsWho this might be right forAdvanced Solid Tumors (Including GCTTS) Dragonboat Biopharmaceutical Company Limited 90
Not applicableLooking for participantsNCT04635111What this trial is testingA Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) TreatmentWho this might be right forHepatotoxicityTenosynovial Giant Cell Tumor Daiichi Sankyo 30
Testing effectiveness (Phase 2)Study completedNCT01207492What this trial is testingNilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell TumorWho this might be right forPigmented Villonodular SynovitisDiffuse-type Giant Cell TumorTenosynovial Giant Cell Tumor Andrew J. Wagner, MD, PhD 17
Not applicableStudy completedNCT02948088What this trial is testingTenosynovial Giant Cell Tumors (TGCT) Observational Platform ProjectWho this might be right forGiant Cell Tumors Daiichi Sankyo 183