Testing effectiveness (Phase 2)WithdrawnNCT03767439What this trial is testingNivolumab With Vismodegib in Patients With Basal Cell Nevus SyndromeWho this might be right forBasal Cell Nevus Syndrome Columbia University
Testing effectiveness (Phase 2)Study completedNCT00961896What this trial is testingA Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome PatientsWho this might be right forTreatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients Novartis Pharmaceuticals 18
Early research (Phase 1)Study completedNCT00433485What this trial is testingTopical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy ParticipantsWho this might be right forNeoplastic SyndromeNon-melanomatous Skin Cancer Yale University 16
Large-scale testing (Phase 3)Study completedNCT06050122What this trial is testingEfficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin SyndromeWho this might be right forGorlin Syndrome Sol-Gel Technologies, Ltd. 113
Testing effectiveness (Phase 2)Study completedNCT01556009What this trial is testingTrial Comparing the Effects of Intermittent Vismodegib vs. PDT in Patients With Multiple Basal Cell CarcinomasWho this might be right forBasal Cell Nevus SyndromeGorlin's Syndrome UCSF Benioff Children's Hospital Oakland 24
Not applicableStudy completedNCT00555633What this trial is testingUse of an SPF30 Sunscreen and an After-sun-lotion in Skin Cancer Risk PatientsWho this might be right forSkin CancerXeroderma PigmentosumBasal Cell Nevus Syndrome Medical University of Graz 13
Not applicableLooking for participantsNCT03050268What this trial is testingFamilial Investigations of Childhood Cancer PredispositionWho this might be right forAcute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more St. Jude Children's Research Hospital 1,500
Testing effectiveness (Phase 2)Study completedNCT00783965What this trial is testingTopical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and BackWho this might be right forSkin Carcinoma UCSF Benioff Children's Hospital Oakland 34
Testing effectiveness (Phase 2)Ended earlyNCT02002689What this trial is testingLDE225 for Patients With PTCH1 or SMO Mutated TumorsWho this might be right forPTCH1 or SMO Activated Solid and Hematologic Tumors Novartis Pharmaceuticals 10
Testing effectiveness (Phase 2)Study completedNCT02550678What this trial is testingThe Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell CarcinomaWho this might be right forBasal Cell Nevus SyndromeSkin NeoplasmNodular Basal Cell Carcinoma of Skin Ascend Biopharmaceuticals Ltd 16
Early research (Phase 1)Looking for participantsNCT06623201What this trial is testingBlue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell CarcinomasWho this might be right forBasal Cell Carcinoma (BCC) Nathalie Zeitouni 20
Not applicableEnrolling By InvitationNCT06330324What this trial is testingReproductive Options in Inherited Skin DiseasesWho this might be right forIchthyosisPalmoplantar KeratosesEpidermolysis Bullosa+7 more Maastricht University Medical Center 650
Not applicableStudy completedNCT00005660What this trial is testingThe Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive DiseasesWho this might be right forBasal Cell CarcinomaKeratosis Palmaris et PlantarisPsoriasis National Cancer Institute (NCI) 130
Large-scale testing (Phase 3)Study completedNCT03703310What this trial is testingStudy of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)Who this might be right forBasal Cell Nevus Syndrome Sol-Gel Technologies, Ltd. 174
Not applicableLooking for participantsNCT05463757What this trial is testingOral Hedgehog Inhibitors in the Treatment of Basal Cell Carcinoma in the Netherlands: a Prospective Registration StudyWho this might be right forBasal Cell CarcinomaLocally Advanced Basal Cell CarcinomaMetastatic Basal Cell Carcinoma+8 more Maastricht University Medical Center 80
Not applicableLooking for participantsNCT06330350What this trial is testingQualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive CounsellingWho this might be right forQuality of LifeIchthyosisPalmoplantar Keratoses+7 more Maastricht University Medical Center 25
Not applicableLooking for participantsNCT04569149What this trial is testingPrimordial Dwarfism RegistryWho this might be right forMOPDIIMeier-Gorlin SyndromeSaul-Wilson Syndrome+4 more Nemours Children's Clinic 200
Early research (Phase 1)Study completedNCT03467789What this trial is testingVitamin D as a Nutritional Neoadjuvant During Photodynamic Therapy of Basal Cell CarcinomaWho this might be right forBasal Cell CarcinomaBasal Cell Nevus Syndrome Case Comprehensive Cancer Center 37
Testing effectiveness (Phase 2)Study completedNCT00023621What this trial is testingCelecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus SyndromeWho this might be right forNon-melanomatous Skin Cancer University of California, San Francisco 60
Testing effectiveness (Phase 2)Study completedNCT01350115What this trial is testingEfficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)Who this might be right forBasal Cell CarcinomaGorlin SyndromeNevoid Basal Cell Carcinoma Syndrome Novartis Pharmaceuticals 10