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Results for “Grade IV Malignant Glioma”

119 trials

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Showing 20 of 119 results

Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Ended earlyNCT02664363
What this trial is testing

EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant Glioma

Who this might be right for
GlioblastomaGliosarcoma
Daniel Landi 3
Early research (Phase 1)Active Not RecruitingNCT07031765
What this trial is testing

Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma

Who this might be right for
Recurrent High-grade GliomaGrade III AstrocytomaOligodendroglioma+3 more
University of Florida 12
Testing effectiveness (Phase 2)Study completedNCT02858895
What this trial is testing

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Who this might be right for
GlioblastomaGrade IV AstrocytomaGlioblastoma Multiforme+1 more
Medicenna Therapeutics, Inc. 47
Not applicableStudy completedNCT05229198
What this trial is testing

ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas

Who this might be right for
Astrocytoma, Grade IV
Juan M Garcia-Gomez 300
Early research (Phase 1)Study completedNCT01491893
What this trial is testing

PVSRIPO for Recurrent Glioblastoma (GBM)

Who this might be right for
GBMGlioblastomaGlioma+1 more
Istari Oncology, Inc. 61
Not applicableNot Yet RecruitingNCT07366892
What this trial is testing

Leica Microsystems Sponsored PMCF Study to Collect and Confirm Clinical Data on the Performance of the GLOW400 Device When Used in Accordance With Its Intended Use

Who this might be right for
Suspected Grade III and IV Gliomas Requiring Surgical InterventionNeurosurgical ProcedureGlioma+1 more
Leica Microsystems (Schweiz) AG 37
Not applicableStudy completedNCT02041611
What this trial is testing

Prospective Evaluation of T-cell Immune Status in Patients With Newly Diagnosed High Grade Gliomas

Who this might be right for
High Grade Glioma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Early research (Phase 1)Study completedNCT04430842
What this trial is testing

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Who this might be right for
AstrocytomaBrain CancerBrain Metastases+20 more
Quadriga Biosciences, Inc. 15
Early research (Phase 1)Study completedNCT03615404
What this trial is testing

Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma

Who this might be right for
GlioblastomaMalignant GliomaMedulloblastoma Recurrent+3 more
Gary Archer Ph.D. 11
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Not applicableEnded earlyNCT02967380
What this trial is testing

Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases

Who this might be right for
Adult Anaplastic (Malignant) MeningiomaAdult Anaplastic AstrocytomaAdult Anaplastic Ependymoma+22 more
University of Southern California 14
Not applicableEnded earlyNCT01515085
What this trial is testing

MRI-Guided Laser Induced Thermal Therapy

Who this might be right for
Malignant Glioma
Rutgers, The State University of New Jersey 1
Early research (Phase 1)Study completedNCT02575794
What this trial is testing

Terameprocol in Treating Patients With Recurrent High Grade Glioma

Who this might be right for
High Grade Glioma (III or IV)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 20
Testing effectiveness (Phase 2)Study completedNCT02330562
What this trial is testing

Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab

Who this might be right for
Malignant GliomaGlioblastoma
Celgene 121
Not applicableLooking for participantsNCT07488754
What this trial is testing

Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) In Newly Diagnosed Glioma (WHO G3-G4)

Who this might be right for
GlioblastomaHigh-Grade Glioma (WHO III-IV)Glioblastoma (GBM)
Medical University of Warsaw 35
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Early research (Phase 1)Ended earlyNCT00272870
What this trial is testing

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

Who this might be right for
Glioblastoma Multiforme (WHO Grade IV)Anaplastic Astrocytoma (WHO Grade III)
Children's Hospital Medical Center, Cincinnati 1
Testing effectiveness (Phase 2)Study completedNCT00005952
What this trial is testing

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorHead and Neck Cancer+5 more
Duke University 30
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
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