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Results for “Granulin Mutation”

5 trials

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Showing 5 of 5 results

Testing effectiveness (Phase 2)UnknownNCT02149160
What this trial is testing

Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Who this might be right for
Granulin Mutation
FORUM Pharmaceuticals Inc 30
Testing effectiveness (Phase 2)Looking for participantsNCT04747431
What this trial is testing

PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Who this might be right for
Frontotemporal DementiaFTDFTD-GRN+2 more
Passage Bio, Inc. 30
Early research (Phase 1)Study completedNCT03636204
What this trial is testing

A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation

Who this might be right for
HealthyFrontotemporal Dementia
Alector Inc. 64
Testing effectiveness (Phase 2)Study completedNCT03987295
What this trial is testing

Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

Who this might be right for
Frontotemporal Dementia
Alector Inc. 33
Testing effectiveness (Phase 2)Looking for participantsNCT06064890
What this trial is testing

Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

Who this might be right for
Frontotemporal DementiaFTDFTD-GRN+1 more
AviadoBio Ltd 18