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Results for “HER2 Low Breast Carcinoma”

201 trials

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Showing 20 of 201 results

Not applicableNot Yet RecruitingNCT07389200
What this trial is testing

Application of Multimodal MRI-based Radiomics in Histological Grading and Prognostic Assessment of Breast Cancer

Who this might be right for
Breast CancerBreast Cancer With Low to Intermediate HER2 Expression
Hao Xu 400
Not applicableStudy completedNCT07211451
What this trial is testing

Axillary Nodal Burden in HER2+ and TNBC

Who this might be right for
Breast Cancer
Gangnam Severance Hospital 1,571
Large-scale testing (Phase 3)Active Not RecruitingNCT05705401
What this trial is testing

Testing Radiation and HER2-targeted Therapy Versus HER2-targeted Therapy Alone for Low-risk HER2-positive Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
NRG Oncology 1,300
Large-scale testing (Phase 3)Looking for participantsNCT05950945
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HER2-low or HER2 IHC 0 Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Daiichi Sankyo 250
Testing effectiveness (Phase 2)Looking for participantsNCT06340230
What this trial is testing

SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in HR Positive/HER2 Low Breast Cancer

Who this might be right for
HR Positive/HER2 Low Breast Cancer
Shengjing Hospital 93
Testing effectiveness (Phase 2)Study completedNCT02048059
What this trial is testing

ANG1005 in Breast Cancer Patients With Recurrent Brain Metastases

Who this might be right for
Breast CancerBrain Metastases
Angiochem Inc 72
Testing effectiveness (Phase 2)Looking for participantsNCT06176534
What this trial is testing

Combination Followed by Maintenance Chemotherapy Versus CDK4/6 Inhibitor Combined With Endocrine Therapy for HR Low/HER2-negative Advanced Breast Cancer: a Prospective, Randomized, Open-label Phase Ⅱ Clinical Trial

Who this might be right for
Advanced Breast CancerTreatmentHR Low/HER2 Negative
Henan Cancer Hospital 240
Not applicableStudy completedNCT04807595
What this trial is testing

Estimation of the Prevalence of HER2 Low and Describe the SoC, Treatment Patterns, and Outcome in Real-world Practice Among Unresectable and/or Metastatic Breast Cancer Patients With HER2 Low Status

Who this might be right for
Breast Cancer
AstraZeneca 798
Testing effectiveness (Phase 2)Study completedNCT00900627
What this trial is testing

Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II)

Who this might be right for
NeoplasmsBreast NeoplasmsBreast Cancer
AstraZeneca 330
Large-scale testing (Phase 3)Active Not RecruitingNCT04494425
What this trial is testing

Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer

Who this might be right for
Advanced or Metastatic Breast Cancer
AstraZeneca 866
Testing effectiveness (Phase 2)Looking for participantsNCT07198724
What this trial is testing

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerHER2 Low Breast CarcinomaHER2-negative Breast Cancer+2 more
Kristina A. Fanucci 65
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06680596
What this trial is testing

Detecting Tumor DNA in the Blood of HR+/HER2-low Metastatic Breast Cancer Patients to Find Candidates for T-DXd Therapy

Who this might be right for
Breast Cancer MetastaticBreast Cancer Stage IV
UNICANCER 80
Large-scale testing (Phase 3)Looking for participantsNCT07762885
What this trial is testing

Omission of Adjuvant Radiotherapy in Low- and Intermediate-Risk Ductal Carcinoma In Situ After Breast-Conserving Surgery

Who this might be right for
Ductal Carcinoma In Situ, DCIS
Fudan University 636
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07317778
What this trial is testing

Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer

Who this might be right for
Breast Cancer Early Stage Breast Cancer (Stage 1-3)HR Positive/HER2 Low Breast Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 249
Testing effectiveness (Phase 2)Looking for participantsNCT06439771
What this trial is testing

Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC

Who this might be right for
Locally Advanced or Metastatic Breast Cancer
MediLink Therapeutics (Suzhou) Co., Ltd. 180
Testing effectiveness (Phase 2)Ended earlyNCT04578106
What this trial is testing

Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy

Who this might be right for
HER2-positive Breast CancerStage I Breast Cancer
Fundacio Clinic Barcelona 5
Early research (Phase 1)Looking for participantsNCT06331169
What this trial is testing

Anlotinib With Trastuzumab Deruxtecan for Previously Treated HER2-Low Advanced Breast Cancer

Who this might be right for
Breast Cancer
Fudan University 42
Testing effectiveness (Phase 2)Looking for participantsNCT06224673
What this trial is testing

ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer

Who this might be right for
HER2 Low Breast CarcinomaTriple Negative Breast CancerHormone-receptor-positive Breast Cancer+1 more
Laura Huppert, MD, BA 36
Testing effectiveness (Phase 2)Looking for participantsNCT07203729
What this trial is testing

The Efficacy and Safety of Trastuzumab Rezetecan (SHR-A1811) in HER2-Low Unresectable/Metastatic Breast Cancer Patients With Visceral Crisis

Who this might be right for
HER2-Low Unresectable/Metastatic Breast Cancer Complicated With Visceral Crisis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 184
Post-approval studies (Phase 4)WithdrawnNCT03238703
What this trial is testing

Endocrine Therapy in Treating Patients With HER2 Negative, Low Risk Breast Cancer

Who this might be right for
HER2/Neu NegativeInvasive Breast CarcinomaPostmenopausal+2 more
Fred Hutchinson Cancer Center
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