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Results for “HER2-Gastric/Gastroesophageal Junction Cancer”

159 trials

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Showing 20 of 159 results

Testing effectiveness (Phase 2)UnknownNCT05241899
What this trial is testing

A Phase II Clinical Study of Fruquintinib Combined With RC48 in the Treatment of Previously Treated HER2-positive Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (G/GEJ) Cancer

Who this might be right for
Gastric Cancer
The First Affiliated Hospital of Zhengzhou University 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT05715931
What this trial is testing

Perioperative Chemotherapy Plus Trastuzumab Plus Toripalimab in HER2 Positive Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Who this might be right for
Adenocarcinoma of the StomachAdenocarcinoma of Esophagogastric JunctionHER2-positive Gastric Cancer
Yu jiren 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06888037
What this trial is testing

Fruquintinib Combined With PD-1 Inhibitor as First-line Maintenance Therapy for Advanced Gastric Cancer

Who this might be right for
Gastric AdenocarcinomaGEJ AdenocarcinomaFirst-line Therapy+3 more
Ruijin Hospital 55
Large-scale testing (Phase 3)Study completedNCT02581462
What this trial is testing

FLOT vs. FLOT/Herceptin/Pertuzumab for Perioperative Therapy of HER-2 Expressing Gastric or GEJ Cancer

Who this might be right for
Stomach CancerGastroesophageal Junction Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 81
Testing effectiveness (Phase 2)Looking for participantsNCT06324357
What this trial is testing

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Who this might be right for
Metastatic Breast CancerMetastatic Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+2 more
Boehringer Ingelheim 768
Large-scale testing (Phase 3)Looking for participantsNCT07315750
What this trial is testing

Disitamab Vedotin Combined With Trastuzumab and Tislelizumab Versus Chemotherapy Combined With Trastuzumab With or Without Pembrolizumab in HER2-high Expression Advanced Gastric or Gastroesophageal Junction Adenocarcinoma.

Who this might be right for
Gastric Carcinoma
RemeGen Co., Ltd. 555
Not applicableLooking for participantsNCT06902545
What this trial is testing

Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer.

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Korea, Inc.
Early research (Phase 1)Study completedNCT01576666
What this trial is testing

Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors

Who this might be right for
Dose EscalationSafetyPreliminary Efficacy+9 more
Novartis Pharmaceuticals 120
Not applicableActive Not RecruitingNCT07448493
What this trial is testing

Local Treatment Strategies for Brain Metastases of Gastric and Esophageal Cancer

Who this might be right for
Gastric CancerEsophageal CancerBrain Metastases
Blokhin's Russian Cancer Research Center 230
Testing effectiveness (Phase 2)UnknownNCT05111444
What this trial is testing

Camrelizumab Plus Pyrotinib Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Gastric NeoplasmsGastroesophageal Junction Adenocarcinoma
Fudan University 65
Large-scale testing (Phase 3)Not Yet RecruitingNCT07818070
What this trial is testing

A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal Adenocarcinoma

Who this might be right for
Gastric CancerEsophagogastric Junction CancerEsophageal Adenocarcinoma
Ono Pharmaceutical Co., Ltd. 600
Not applicableStudy completedNCT02538562
What this trial is testing

Human Epidermal Growth Factor Receptor 2 (HER2) Advanced Gastric Epidemiology Study in Korea

Who this might be right for
Gastric CancerGastroesophageal Junction Cancer
Hoffmann-La Roche 1,695
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Not applicableStudy completedNCT05892926
What this trial is testing

HER2-positive Locally Advanced/Metastatic Gastric and/or Gastroesophageal Junction (GEJ) Adenocarcinoma in Russia

Who this might be right for
Adenocarcinoma
AstraZeneca 204
Testing effectiveness (Phase 2)Looking for participantsNCT07025889
What this trial is testing

IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer

Who this might be right for
Gastric Cancer
Ruijin Hospital 55
Large-scale testing (Phase 3)Not Yet RecruitingNCT06944496
What this trial is testing

Disitamab Vedotin Combined With Tislelizumab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in HER2-Low Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Carcinoma
RemeGen Co., Ltd. 616
Testing effectiveness (Phase 2)WithdrawnNCT05678205
What this trial is testing

A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors

Who this might be right for
Breast CancerGastric CancerGastroesophageal Junction Adenocarcinoma
Artiva Biotherapeutics, Inc.
Testing effectiveness (Phase 2)Study completedNCT01472029
What this trial is testing

Explorative Phase II Study of Perioperative Treatment in Patients With Adenocarcinoma of the Gastroesophageal Junction or Stomach

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionAdenocarcinoma of the Stomach
AIO-Studien-gGmbH 53
Testing effectiveness (Phase 2)Study completedNCT03929666
What this trial is testing

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

Who this might be right for
HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Jazz Pharmaceuticals 74
Testing effectiveness (Phase 2)Ended earlyNCT05311176
What this trial is testing

IMU-131 (HER-Vaxx) in Combination With Chemotherapy or Pembrolizumab in Patients With Metastatic HER2/Neu Over-Expressing Gastric Cancer (nextHERIZON)

Who this might be right for
Gastric CancerCancer of StomachGastric Adenocarcinoma+3 more
Imugene Limited 7
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