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Results for “HER2-Positive Advanced Biliary Tract Cancer”

27 trials

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Showing 20 of 27 results

Testing effectiveness (Phase 2)UnknownNCT05417230
What this trial is testing

RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2

Who this might be right for
Biliary Tract Cancer
Jiangsu Cancer Institute & Hospital 29
Testing effectiveness (Phase 2)Study completedNCT04722133
What this trial is testing

Trastuzumab-pkrb Combined With Modified FOLFOX-6 in Biliary Tract Cancer Patients Progressed on First Line Therapy

Who this might be right for
HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer
Yonsei University 36
Large-scale testing (Phase 3)Looking for participantsNCT07062263
What this trial is testing

Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients

Who this might be right for
Biliary Tract CancerHER2-positive CancerAdvanced Cancer+2 more
Tata Memorial Centre 220
Early research (Phase 1)UnknownNCT04460456
What this trial is testing

SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid Tumors

Who this might be right for
HER2 Positive Solid Tumors
Silverback Therapeutics 58
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05985707
What this trial is testing

KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma

Who this might be right for
HER2-positive Colorectal CancerHER2-positive Biliary Tract Cancer
Peking University Cancer Hospital & Institute 80
Testing effectiveness (Phase 2)Looking for participantsNCT05969860
What this trial is testing

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Who this might be right for
Advanced Anal CarcinomaAdvanced Biliary Tract CarcinomaAdvanced Bladder Carcinoma+41 more
Mayo Clinic 220
Testing effectiveness (Phase 2)Looking for participantsNCT05523947
What this trial is testing

Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

Who this might be right for
HER2-Positive Solid Tumor
Yuhan Corporation 147
Post-approval studies (Phase 4)Not Yet RecruitingNCT07768358
What this trial is testing

Tucatinib Continuation Study

Who this might be right for
HER2-positive Breast CancerCervical CancerBiliary Tract Neoplasms+4 more
Pfizer 175
Testing effectiveness (Phase 2)UnknownNCT04837508
What this trial is testing

MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer

Who this might be right for
Advanced or Metastatic Biliary Tract Cancer
Shanghai Miracogen Inc. 86
Testing effectiveness (Phase 2)Looking for participantsNCT05749900
What this trial is testing

First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT)

Who this might be right for
HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer
Yonsei University 44
Testing effectiveness (Phase 2)Looking for participantsNCT06778031
What this trial is testing

A Clinical Study of SHR-A1811 in the Treatment of HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer

Who this might be right for
HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd. 54
Early research (Phase 1)UnknownNCT04660929
What this trial is testing

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Who this might be right for
HER2-positiveAdenocarcinomaBile Duct Cancer+28 more
Carisma Therapeutics Inc 48
Early research (Phase 1)UnknownNCT04450732
What this trial is testing

Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors

Who this might be right for
HER2-positive Breast CancerHER2-positive Biliary Tract CancerHER2-Positive Salivary Gland Carcinomas+1 more
GeneQuantum Healthcare (Suzhou) Co., Ltd. 96
Post-approval studies (Phase 4)Not Yet RecruitingNCT06818773
What this trial is testing

Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer

Who this might be right for
Metastatic Biliary Tract CancerHER2 Positive
Eastern Hepatobiliary Surgery Hospital 35
Testing effectiveness (Phase 2)Looking for participantsNCT07704177
What this trial is testing

Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib in Advanced HER2-Positive/Low-Expression Biliary Tract Cancer

Who this might be right for
Biliary Tract Neoplasms Immunotherapy
Peking Union Medical College Hospital 70
Testing effectiveness (Phase 2)Ended earlyNCT04278144
What this trial is testing

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

Who this might be right for
HER2-positive Solid TumorsHER2-positive Breast CancerHER2-positive Colorectal Cancer+2 more
Bolt Biotherapeutics, Inc. 175
Not applicableNo Longer AvailableNCT04578444
What this trial is testing

An Expanded Access Treatment Protocol of Zanidatamab (ZW25) in Patients With HER2-Positive Advanced Biliary Tract Cancer

Who this might be right for
HER2-Positive Advanced Biliary Tract Cancer
Jazz Pharmaceuticals
Testing effectiveness (Phase 2)Looking for participantsNCT05150691
What this trial is testing

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Who this might be right for
HER2-positive Advanced Solid Tumor
DualityBio Inc. 796
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07159217
What this trial is testing

Disitamab Vedotin Plus Lenvatinib and PD-1 Inhibitors for Treating HER2-positive Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract CancerDisitamab VedotinLenvatinib+1 more
Peking Union Medical College Hospital 65
Testing effectiveness (Phase 2)Looking for participantsNCT07670273
What this trial is testing

Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer

Who this might be right for
Biliary Tract Neoplasms Immunotherapy
Peking Union Medical College Hospital 70
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