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Results for “HER2-Positive Advanced Biliary Tract Cancer”

24 trials

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Showing 20 of 24 results

Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Early research (Phase 1)Ended earlyNCT05194072
What this trial is testing

Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsPeritoneal NeoplasmsFallopian Tube Neoplasms+8 more
Seagen, a wholly owned subsidiary of Pfizer 250
Testing effectiveness (Phase 2)Ended earlyNCT04278144
What this trial is testing

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

Who this might be right for
HER2-positive Solid TumorsHER2-positive Breast CancerHER2-positive Colorectal Cancer+2 more
Bolt Biotherapeutics, Inc. 175
Testing effectiveness (Phase 2)UnknownNCT04837508
What this trial is testing

MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer

Who this might be right for
Advanced or Metastatic Biliary Tract Cancer
Shanghai Miracogen Inc. 86
Early research (Phase 1)Ended earlyNCT04209465
What this trial is testing

BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.

Who this might be right for
Solid Tumor
Black Diamond Therapeutics, Inc. 91
Testing effectiveness (Phase 2)Looking for participantsNCT06431490
What this trial is testing

TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. 103
Post-approval studies (Phase 4)Not Yet RecruitingNCT06818773
What this trial is testing

Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer

Who this might be right for
Metastatic Biliary Tract CancerHER2 Positive
Eastern Hepatobiliary Surgery Hospital 35
Testing effectiveness (Phase 2)Ended earlyNCT00478140
What this trial is testing

Trastuzumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer or Bile Duct Cancer That Cannot Be Removed by Surgery

Who this might be right for
Adenocarcinoma of the Extrahepatic Bile DuctAdenocarcinoma of the GallbladderMalignant Neoplasm+4 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Looking for participantsNCT05969860
What this trial is testing

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Who this might be right for
Advanced Anal CarcinomaAdvanced Biliary Tract CarcinomaAdvanced Bladder Carcinoma+40 more
Mayo Clinic 200
Testing effectiveness (Phase 2)UnknownNCT05417230
What this trial is testing

RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2

Who this might be right for
Biliary Tract Cancer
Jiangsu Cancer Institute & Hospital 29
Early research (Phase 1)UnknownNCT04460456
What this trial is testing

SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid Tumors

Who this might be right for
HER2 Positive Solid Tumors
Silverback Therapeutics 58
Not applicableNo Longer AvailableNCT04578444
What this trial is testing

An Expanded Access Treatment Protocol of Zanidatamab (ZW25) in Patients With HER2-Positive Advanced Biliary Tract Cancer

Who this might be right for
HER2-Positive Advanced Biliary Tract Cancer
Jazz Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT03602079
What this trial is testing

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

Who this might be right for
HER2-positive Breast CancerHER2 Gene MutationHER-2 Gene Amplification+41 more
Klus Pharma Inc. 49
Testing effectiveness (Phase 2)Looking for participantsNCT05523947
What this trial is testing

Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

Who this might be right for
HER2-Positive Solid Tumor
Yuhan Corporation 137
Large-scale testing (Phase 3)Looking for participantsNCT06282575
What this trial is testing

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
Jazz Pharmaceuticals 286
Testing effectiveness (Phase 2)Study completedNCT04722133
What this trial is testing

Trastuzumab-pkrb Combined With Modified FOLFOX-6 in Biliary Tract Cancer Patients Progressed on First Line Therapy

Who this might be right for
HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer
Yonsei University 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07159217
What this trial is testing

Disitamab Vedotin Plus Lenvatinib and PD-1 Inhibitors for Treating HER2-positive Advanced Biliary Tract Cancer

Who this might be right for
Biliary Tract CancerDisitamab VedotinLenvatinib+1 more
Peking Union Medical College Hospital 65
Testing effectiveness (Phase 2)Looking for participantsNCT05150691
What this trial is testing

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Who this might be right for
HER2-positive Advanced Solid Tumor
DualityBio Inc. 796
Early research (Phase 1)UnknownNCT04450732
What this trial is testing

Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors

Who this might be right for
HER2-positive Breast CancerHER2-positive Biliary Tract CancerHER2-Positive Salivary Gland Carcinomas+1 more
GeneQuantum Healthcare (Suzhou) Co., Ltd. 96
Early research (Phase 1)Active Not RecruitingNCT04660929
What this trial is testing

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Who this might be right for
HER2-positiveAdenocarcinomaBile Duct Cancer+28 more
Carisma Therapeutics Inc 48
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