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Results for “HER2-positive Biliary Tract Cancer”

34 trials

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Showing 20 of 34 results

Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Testing effectiveness (Phase 2)Looking for participantsNCT07704177
What this trial is testing

Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib in Advanced HER2-Positive/Low-Expression Biliary Tract Cancer

Who this might be right for
Biliary Tract Neoplasms Immunotherapy
Peking Union Medical College Hospital 70
Large-scale testing (Phase 3)Looking for participantsNCT07062263
What this trial is testing

Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients

Who this might be right for
Biliary Tract CancerHER2-positive CancerAdvanced Cancer+2 more
Tata Memorial Centre 220
Testing effectiveness (Phase 2)Active Not RecruitingNCT06178445
What this trial is testing

Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract Cancer

Who this might be right for
Biliary Tract CancerHER2 Gene MutationHER2
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 24
Testing effectiveness (Phase 2)Looking for participantsNCT05150691
What this trial is testing

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Who this might be right for
HER2-positive Advanced Solid Tumor
DualityBio Inc. 796
Early research (Phase 1)UnknownNCT04450732
What this trial is testing

Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors

Who this might be right for
HER2-positive Breast CancerHER2-positive Biliary Tract CancerHER2-Positive Salivary Gland Carcinomas+1 more
GeneQuantum Healthcare (Suzhou) Co., Ltd. 96
Large-scale testing (Phase 3)Looking for participantsNCT06282575
What this trial is testing

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Who this might be right for
Biliary Tract Cancer
Jazz Pharmaceuticals 286
Testing effectiveness (Phase 2)Looking for participantsNCT05749900
What this trial is testing

First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT)

Who this might be right for
HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer
Yonsei University 44
Early research (Phase 1)UnknownNCT04660929
What this trial is testing

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Who this might be right for
HER2-positiveAdenocarcinomaBile Duct Cancer+28 more
Carisma Therapeutics Inc 48
Testing effectiveness (Phase 2)Study completedNCT03613168
What this trial is testing

Trastuzumab in HER2-positive Biliary Tract Cancer

Who this might be right for
CholangiocarcinomaBiliary Tract CancerHER-2 Protein Overexpression+1 more
Changhoon Yoo 4
Testing effectiveness (Phase 2)Looking for participantsNCT06434597
What this trial is testing

A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients.

Who this might be right for
Biliary Tract or Colorectal Cancer With Her2-positive/Mutated
Shanghai Pharmaceuticals Holding Co., Ltd 60
Post-approval studies (Phase 4)Not Yet RecruitingNCT06818773
What this trial is testing

Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer

Who this might be right for
Metastatic Biliary Tract CancerHER2 Positive
Eastern Hepatobiliary Surgery Hospital 35
Early research (Phase 1)Ended earlyNCT04209465
What this trial is testing

BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.

Who this might be right for
Solid Tumor
Black Diamond Therapeutics, Inc. 91
Early research (Phase 1)Ended earlyNCT05194072
What this trial is testing

Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsPeritoneal NeoplasmsFallopian Tube Neoplasms+8 more
Seagen, a wholly owned subsidiary of Pfizer 250
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05985707
What this trial is testing

KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma

Who this might be right for
HER2-positive Colorectal CancerHER2-positive Biliary Tract Cancer
Peking University Cancer Hospital & Institute 80
Testing effectiveness (Phase 2)UnknownNCT05417230
What this trial is testing

RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2

Who this might be right for
Biliary Tract Cancer
Jiangsu Cancer Institute & Hospital 29
Early research (Phase 1)UnknownNCT04460456
What this trial is testing

SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid Tumors

Who this might be right for
HER2 Positive Solid Tumors
Silverback Therapeutics 58
Testing effectiveness (Phase 2)UnknownNCT04837508
What this trial is testing

MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer

Who this might be right for
Advanced or Metastatic Biliary Tract Cancer
Shanghai Miracogen Inc. 86
Testing effectiveness (Phase 2)Study completedNCT04722133
What this trial is testing

Trastuzumab-pkrb Combined With Modified FOLFOX-6 in Biliary Tract Cancer Patients Progressed on First Line Therapy

Who this might be right for
HER2 Positive Advanced/Metastatic/Nonresectable Biliary Tract Cancer
Yonsei University 36
Not applicableNo Longer AvailableNCT04578444
What this trial is testing

An Expanded Access Treatment Protocol of Zanidatamab (ZW25) in Patients With HER2-Positive Advanced Biliary Tract Cancer

Who this might be right for
HER2-Positive Advanced Biliary Tract Cancer
Jazz Pharmaceuticals
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