Early research (Phase 1)Study completedNCT01133912What this trial is testingPreoperative Chemotherapy With Paclitaxel, Gemcitabine, and Lapatinib (Tykerb®) (PGT)Who this might be right forBreast Cancer Jungsil Ro 13
Testing effectiveness (Phase 2)Looking for participantsNCT06518837What this trial is testingTirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast CancerWho this might be right forHormone Receptor-Positive Breast CancerHER2-Negative Breast Cancer Rutgers, The State University of New Jersey 40
Not applicableStudy completedNCT05377684What this trial is testingStudy of Quality of Life and Hormone Levels in Premenopausal Participants With Early Breast Cancer Receiving Triptorelin Plus Additional Cancer TreatmentWho this might be right forEarly-stage Breast Cancer Ipsen 450
Not applicableEnrolling By InvitationNCT07132749What this trial is testingNEPA in Patients With HER2-positive or HER2-low Advanced Breast Cancer Treated With T-DXdWho this might be right forPatients With HER2-positive Advanced Breast Cancer Treated With T-DXdPatients With HER2-low Advanced Breast Cancer Treated With T-DXd Yeon Hee Park 100
Not applicableActive Not RecruitingNCT06868758What this trial is testingPredictive Value of Tumor Vascular Normalization Scoring in HER-2 Positive Breast CancerWho this might be right forHER2 Positive Breast CarcinomaNeoadjuvant Therapy Chongqing General Hospital 50
Early research (Phase 1)Study completedNCT01226316What this trial is testingSafety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment SchedulesWho this might be right forAdvanced Solid MalignancySafety and TolerabilityPharmacokinetics+11 more AstraZeneca 285
Testing effectiveness (Phase 2)UnknownNCT01428414What this trial is testingEfficacy and Safety Study of Trastuzumab and Paclitaxel Based Regimens to Treat HER2-positive Breast CancerWho this might be right forHER-2 Positive Breast Cancer Zhimin Shao 100
Testing effectiveness (Phase 2)Looking for participantsNCT07053085What this trial is testingSurgery and Radiotherapy in People With Breast CancerWho this might be right forMetastatic Breast CancerHER2-positive Breast Cancer Memorial Sloan Kettering Cancer Center 178
Testing effectiveness (Phase 2)Looking for participantsNCT06016387What this trial is testingTucatinib, Trastuzumab and Capecitabine With Brain and/or Spinal Radiotherapy (XRT) in Patients With HER2+, HER2 Mutated and/or HER2-amplified Metastatic Breast Cancer and Leptomeningeal Disease: A Multi-centre Phase II, Single Arm Feasibility StudyWho this might be right forHER2-positive Breast CancerLMD Sunnybrook Health Sciences Centre 30
Large-scale testing (Phase 3)Study completedNCT00054587What this trial is testingCombination Chemotherapy With or Without Trastuzumab in Treating Women With Breast CancerWho this might be right forBreast Cancer UNICANCER 3,010
Testing effectiveness (Phase 2)Active Not RecruitingNCT04553133What this trial is testingPF-07104091 as a Single Agent and in Combination TherapyWho this might be right forSmall Cell Lung CancerOvarian CancerBreast Cancer Pfizer 157
Post-approval studies (Phase 4)Looking for participantsNCT07195344What this trial is testingStudy Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.Who this might be right forLocally Advanced or Metastatic Breast Cancers Institut Claudius Regaud 210
Large-scale testing (Phase 3)Active Not RecruitingNCT04191499What this trial is testingA Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast CancerWho this might be right forBreast Cancer Hoffmann-La Roche 325
Not applicableStudy completedNCT06003114What this trial is testingUnderstand the Use of Palbociclib in Canadian Patients With Breast Cancer That Has Spread to Other OrgansWho this might be right forBreast Cancer Pfizer 472
Not applicableStudy completedNCT05955833What this trial is testing89Zr-DFO*-Trastuzumab PET in Patients With Gastric or Breast Cancer - a Pilot StudyWho this might be right forBreast CancerMetastatic Breast CancerHER2-positive Breast Cancer+3 more Amsterdam UMC, location VUmc 6
Early research (Phase 1)Study completedNCT00614978What this trial is testingLapatinib and Temozolomide for the Treatment of Progressive Brain Disease in HER-2 Positive Breast CancerWho this might be right forMetastatic Breast CancerBrain MetastasesHER2 Positive Jules Bordet Institute 18
Early research (Phase 1)Study completedNCT01791478What this trial is testingBYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast CancerWho this might be right forEstrogen Receptor-positive Breast CancerHER2-negative Breast CancerInvasive Ductal Breast Carcinoma+3 more Vanderbilt-Ingram Cancer Center 46
Large-scale testing (Phase 3)Study completedNCT01084876What this trial is testingDemonstrate Efficacy and Safety of Metastatic Breast CancerWho this might be right forMetastatic Breast Cancer Celltrion 475
Testing effectiveness (Phase 2)Active Not RecruitingNCT04550494What this trial is testingMeasuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair VariationsWho this might be right forAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate Carcinoma+28 more National Cancer Institute (NCI) 29
Not applicableNot Yet RecruitingNCT07662252What this trial is testingCirculating Tumor DNA Dynamics to Optimize Neoadjuvant Therapy in HER2-Positive and Triple-Negative Breast CancerWho this might be right forBreast CancerTriple Negative Breast Cancer (TNBC)HER2 + Breast Cancer Federico II University 186