Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “HFrEF - Heart Failure With Reduced Ejection Fraction”

389 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 389 results

Early research (Phase 1)Study completedNCT05328752
What this trial is testing

Safety and Tolerability Study of XXB750 in Heart Failure Participants With Reduced or Mildly Reduced Ejection Fraction (HFrEF/HFmrEF)

Who this might be right for
Heart Failure With Reduced Ejection Fraction (HFrEF)or Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
Novartis Pharmaceuticals 27
Post-approval studies (Phase 4)Not Yet RecruitingNCT06704633
What this trial is testing

Sacubitril-valsartan in Patients With Heart Failure With Reduced Ejection Fraction From Rural Tanzania

Who this might be right for
Heart Failure
Martin Rohacek 238
Post-approval studies (Phase 4)Study completedNCT04197635
What this trial is testing

Short-term Effects of Dapagliflozin on Peak VO2 in HFrEF

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Fundación para la Investigación del Hospital Clínico de Valencia 74
Not applicableWithdrawnNCT05806970
What this trial is testing

Email Nudges to Improve GDMT (MRA) Adherence in Heart Failure

Who this might be right for
Heart Failure With Reduced Ejection Fraction
University of California, Los Angeles
Not applicableStudy completedNCT06697353
What this trial is testing

An Observational Study to Learn More About the Real-world Outcomes in Patients With Heart Failure Who Initiate Treatment With Vericiguat in Japan

Who this might be right for
Chronic Heart FailureChronic Heart Failure With Reduced Ejection Fraction
Bayer 4,936
Not applicableLooking for participantsNCT06543446
What this trial is testing

Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy

Who this might be right for
Heart Failure With Reduced Ejection Fraction
University of Rochester 3,290
Not applicableNot Yet RecruitingNCT06551012
What this trial is testing

Neuromuscular Fatigability in Individuals With Heart Failure

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Newcastle University 28
Not applicableUnknownNCT04638764
What this trial is testing

Resistance Training in Cardiovascular Disease Patients

Who this might be right for
Coronary Artery DiseaseHeart Failure With Reduced Ejection Fraction
General Hospital Murska Sobota 72
Early research (Phase 1)Study completedNCT04210375
What this trial is testing

Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Salubris Biotherapeutics Inc 14
Not applicableStudy completedNCT05981144
What this trial is testing

Exploration of Clonal Hematopoiesis of Indeterminate Potential in Non-ischemic Heart Failure With Reduced Ejection Fraction

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Yonsei University 100
Testing effectiveness (Phase 2)Study completedNCT03791593
What this trial is testing

EVOlocumab in Stable Heart Failure With Reduced Ejection Fraction of Ischemic Etiology: EVO-HF Pilot

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Fundació Institut Germans Trias i Pujol 46
Post-approval studies (Phase 4)Not Yet RecruitingNCT06427200
What this trial is testing

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Cairo University 114
Post-approval studies (Phase 4)Looking for participantsNCT05583773
What this trial is testing

SHengXIaN-QuYu DEcoction in Heart Failure With Reduced and Mildly Reduced Ejection Fraction

Who this might be right for
Heart Failure
China-Japan Friendship Hospital 336
Not applicableEnded earlyNCT03479424
What this trial is testing

Home Outpatient Monitoring and Engagement to Predict HF Exacerbation

Who this might be right for
Heart Failure With Reduced Ejection Fraction
University of California, San Francisco 30
Post-approval studies (Phase 4)Study completedNCT04385589
What this trial is testing

Dapagliflozin in Diabetic Patients (Type 2) With Decompensated Heart Failure

Who this might be right for
Heart Failure
Assiut University 100
Large-scale testing (Phase 3)Looking for participantsNCT05553886
What this trial is testing

S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction
Shenzhen People's Hospital 5
Post-approval studies (Phase 4)UnknownNCT04200586
What this trial is testing

The Effects of SGLTi on Diabetic Cardiomyopathy

Who this might be right for
Type2 DiabetesHeart Failure With Reduced Ejection Fraction
The University of Hong Kong 30
Not applicableWithdrawnNCT04455828
What this trial is testing

Wearable Remote Monitoring of Heart Rate and Respiratory Rate for Heart Failure

Who this might be right for
Heart FailureHeart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection Fraction
Milton S. Hershey Medical Center
Not applicableLooking for participantsNCT06774014
What this trial is testing

Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences

Who this might be right for
Diabetes Mellitus Type 2Heart FailureHFrEF - Heart Failure With Reduced Ejection Fraction+1 more
University of Leeds 600
Not applicableLooking for participantsNCT06384963
What this trial is testing

Respiratory Sinus Arrhythmia Pacing Post-CABG Surgery in Patients With HFrEF

Who this might be right for
Heart Failure With Reduced Ejection Fraction
Ceryx Medical Australia 54
Load More Results