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Results for “HGSOC”

30 trials

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Showing 20 of 30 results

Testing effectiveness (Phase 2)Ended earlyNCT04718675
What this trial is testing

KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Who this might be right for
Relapsed Solid TumorsRefractory Solid TumorsNon-Hodgkin Lymphoma+2 more
Kronos Bio 135
Early research (Phase 1)Looking for participantsNCT06799065
What this trial is testing

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Who this might be right for
Advanced Solid TumorsBreast Cancer RecurrentOvarian Cancer+2 more
Accent Therapeutics 90
Not applicableStudy completedNCT06787170
What this trial is testing

Prediction of Platinum Resistance and Prognosis of High-grade Serous Ovarian Cancer

Who this might be right for
High-grade Serous Ovarian Cancer (HGSOC)
The First People's Hospital of Yunnan 1,129
Early research (Phase 1)Study completedNCT02307240
What this trial is testing

Open Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Subjects With Advanced/Relapsed Solid Tumors

Who this might be right for
Triple-Negative Breast CancerHigh-grade Serous Ovarian CancerSolid Tumors+1 more
Curis, Inc. 43
Not applicableNot Yet RecruitingNCT07366242
What this trial is testing

Prognostic Value of (DHODH) Expression in (HGSOC): A Comparative Study Between Neoadjuvant and Adjuvant Chemotherapy Settings

Who this might be right for
HGSOC
Heba Ahmed Mohamed 72
Early research (Phase 1)Looking for participantsNCT07503808
What this trial is testing

IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

Who this might be right for
Esophageal Squamous Cell CarcinomaHigh Grade Serous Ovarian CancerHead and Neck Squamous Cell Carcinoma+5 more
IDEAYA Biosciences 150
Not applicableLooking for participantsNCT04846933
What this trial is testing

Multi-layer Data to Improve Diagnosis, Predict Therapy Resistance and Suggest Targeted Therapies in HGSOC

Who this might be right for
High Grade Ovarian Serous AdenocarcinomaHigh Grade Serous Carcinoma
Turku University Hospital 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07432594
What this trial is testing

Neoadjuvant Aitua (PD-1/CTLA-4 Bispecific) Plus Nab-Paclitaxel and Carboplatin for Advanced High-Grade Serous Ovarian Cancer

Who this might be right for
High-grade Serous Ovarian Cancer (HGSOC)Fallopian Tube CancersPrimary Peritoneal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 82
Early research (Phase 1)Looking for participantsNCT04389632
What this trial is testing

Sigvotatug Vedotin in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer 1,006
Testing effectiveness (Phase 2)Ended earlyNCT03311334
What this trial is testing

DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Urothelial CarcinomaPrimary Peritoneal Cancer+3 more
Sumitomo Pharma America, Inc. 47
Not applicableEnded earlyNCT03922776
What this trial is testing

Phenotypic Characterization Tumor-infiltrating Lymphocytes at Diagnosis and After Chemotherapy in Ovarian Cancer

Who this might be right for
Ovarian Cancer Stage IIICFallopian Tube Cancer Stage IIICFallopian Tube Cancer Stage IV+1 more
Centre Oscar Lambret 36
Early research (Phase 1)Study completedNCT04293094
What this trial is testing

Study of AMG 650 in Adult Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Volastra Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Looking for participantsNCT05985655
What this trial is testing

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)Pancreatic AdenocarcinomaNon-small Cell Lung Cancer (NSCLC)+3 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc. 230
Early research (Phase 1)Active Not RecruitingNCT04092270
What this trial is testing

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Who this might be right for
Endometrial High Grade Endometrioid AdenocarcinomaFallopian Tube Clear Cell AdenocarcinomaFallopian Tube Endometrioid Adenocarcinoma+26 more
National Cancer Institute (NCI) 54
Not applicableLooking for participantsNCT06466382
What this trial is testing

OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy

Who this might be right for
Ovarian Neoplasm EpithelialFallopian Tube NeoplasmsOvarian Endometrioid Carcinoma+1 more
Swiss GO Trial Group 60
Testing effectiveness (Phase 2)WithdrawnNCT02756130
What this trial is testing

Birinapant and Carboplatin in Treating Patients and Targeting Recurrent High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (HGSOC)

Who this might be right for
High Grade Fallopian Tube Serous AdenocarcinomaHigh Grade Ovarian Serous AdenocarcinomaPrimary Peritoneal High Grade Serous Adenocarcinoma+3 more
Jonsson Comprehensive Cancer Center
Testing effectiveness (Phase 2)WithdrawnNCT05714306
What this trial is testing

PEP-DC and OC-DC Vaccine in High Grade Serous Ovarian Carcinoma

Who this might be right for
Ovarian Carcinoma
Centre Hospitalier Universitaire Vaudois
Not applicableNot Yet RecruitingNCT07461207
What this trial is testing

A Translational Study to Explore and Overcome Metabolic-driven Resistance Mechanisms to Standard Chemotherapy in High-grade Ovarian Cancer

Who this might be right for
High-grade Serous Ovarian Carcinoma (HGSOC)
IRCCS Azienda Ospedaliero-Universitaria di Bologna 120
Testing effectiveness (Phase 2)Looking for participantsNCT06188520
What this trial is testing

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

Who this might be right for
ER+ HER2- Advanced Breast CancerHigh-grade Serous Ovarian Cancer (HGSOC)
AstraZeneca 564
Early research (Phase 1)Looking for participantsNCT06476808
What this trial is testing

Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Who this might be right for
High-grade Serous Ovarian Carcinoma (HGSOC)Uterine Serous Carcinoma (USC)Non-small Cell Lung Cancer (NSCLC)
Bristol-Myers Squibb 240
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