Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “HIGH GRADE GLIOMA”

1,019 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 1,019 results

Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Very early researchLooking for participantsNCT06829173
What this trial is testing

Concurrent XRD-0394 With Radiation Therapy for High Grade Gliomas

Who this might be right for
High-Grade Glioma
NYU Langone Health 39
Large-scale testing (Phase 3)Study completedNCT01781468
What this trial is testing

Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma

Who this might be right for
Fatigue
Alliance for Clinical Trials in Oncology 328
Early research (Phase 1)Study completedNCT00052780
What this trial is testing

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+22 more
National Cancer Institute (NCI) 72
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Looking for participantsNCT06630260
What this trial is testing

5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours

Who this might be right for
Glioblastoma Multiforme (GBM)Glioblastoma Multiform (Grade IV Astrocytoma)Diffuse Hemispheric Glioma, H3 G34-Mutant+1 more
Institute of Cancer Research, United Kingdom 182
Testing effectiveness (Phase 2)Study completedNCT00014573
What this trial is testing

Chemotherapy and Vaccine Therapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Recurrent or Refractory Brain Cancer

Who this might be right for
Brain and Central Nervous System Tumors
Barbara Ann Karmanos Cancer Institute
Early research (Phase 1)Study completedNCT01792505
What this trial is testing

Dendritic Cell Vaccine With Imiquimod for Patients With Malignant Glioma

Who this might be right for
Malignant Glioma
Cedars-Sinai Medical Center 71
Testing effectiveness (Phase 2)Looking for participantsNCT06818331
What this trial is testing

Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial

Who this might be right for
Glioma
The Third Affiliated hospital of Zhejiang Chinese Medical University 20
Early research (Phase 1)Study completedNCT01130077
What this trial is testing

A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

Who this might be right for
Newly Diagnosed Pediatric Pontine GliomaNewly Diagnosed Pediatric High Grade GliomaRecurrent Pediatric High Grade Glioma+1 more
James Felker 60
Testing effectiveness (Phase 2)Study completedNCT00445965
What this trial is testing

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Who this might be right for
Brain and Central Nervous System TumorsIntraocular MelanomaLung Cancer+7 more
Memorial Sloan Kettering Cancer Center 78
Testing effectiveness (Phase 2)Study completedNCT00590954
What this trial is testing

Clinical and Molecular-Metabolic Phase II Trial of Perifosine for Recurrent/Progressive Malignant Gliomas

Who this might be right for
Malignant GliomasCNSBrain Cancer+1 more
Memorial Sloan Kettering Cancer Center 32
Testing effectiveness (Phase 2)Study completedNCT01462695
What this trial is testing

Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or Ependymoma

Who this might be right for
Childhood Cerebellar Anaplastic AstrocytomaChildhood Cerebral Anaplastic AstrocytomaChildhood Cerebral Astrocytoma+8 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00036972
What this trial is testing

Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma

Who this might be right for
Brain and Central Nervous System Tumors
Memorial Sloan Kettering Cancer Center
Not applicableLooking for participantsNCT05212272
What this trial is testing

MRI in High-Grade Glioma Patients Undergoing Chemoradiation

Who this might be right for
High Grade Glioma
Wake Forest University Health Sciences 16
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)Ended earlyNCT02481960
What this trial is testing

Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma

Who this might be right for
Glioma
Boston Scientific Corporation 5
Not applicableStudy completedNCT03323450
What this trial is testing

Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory

Who this might be right for
GliomaBrain Tumor, Primary
Virginia Commonwealth University 20
Testing effectiveness (Phase 2)Study completedNCT00004024
What this trial is testing

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Who this might be right for
Brain and Central Nervous System Tumors
Barbara Ann Karmanos Cancer Institute 60
Next Page