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Results for “HNPCC Gene Mutation”

35 trials

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Showing 20 of 35 results

Not applicableLooking for participantsNCT07450612
What this trial is testing

Liquid Biopsy and Machine Learning for Early Colorectal Cancer, Adenomas, Lynch Cancers, and Residual Disease Detection

Who this might be right for
Colorectal CancerAdenoma ColonAdenoma Colon Polyp+16 more
San Raffaele University 1,200
Not applicableLooking for participantsNCT07498829
What this trial is testing

Population Based Germline Testing for Early Detection and Prevention of Cancer

Who this might be right for
Breast Cancer RiskOvarian Cancer RiskCancer Gene Mutation
Queen Mary University of London 6,000
Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
Not applicableLooking for participantsNCT03124212
What this trial is testing

Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland

Who this might be right for
Hereditary Breast and Ovarian CancerLynch Syndrome
University of Basel 700
Not applicableLooking for participantsNCT06712095
What this trial is testing

Video Capsule Examination in Patients With Lynch Syndrome

Who this might be right for
Lynch SyndromeLi Fraumeni SyndromePTEN Hamartoma Syndrome+7 more
Royal Marsden NHS Foundation Trust 25
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Not applicableTemporarily pausedNCT02993068
What this trial is testing

Stand up to Cancer: MAGENTA (Making Genetic Testing Accessible)

Who this might be right for
BARD1 Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+12 more
M.D. Anderson Cancer Center 5,200
Not applicableActive Not RecruitingNCT05692596
What this trial is testing

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CystChronic Pancreatitis+10 more
H. Lee Moffitt Cancer Center and Research Institute 317
Not applicableActive Not RecruitingNCT00261456
What this trial is testing

The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer

Who this might be right for
Prostate CancerBRCA MutationMismatch Repair Gene Mutation+1 more
Institute of Cancer Research, United Kingdom 3,500
Not applicableUnknownNCT01447199
What this trial is testing

The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)

Who this might be right for
Bladder CancerColorectal CancerEndometrial Cancer+3 more
M.D. Anderson Cancer Center 2,000
Not applicableUnknownNCT02053805
What this trial is testing

Prostate Cancer Screening Among Men With High Risk Genetic Predisposition

Who this might be right for
BRCA1 SyndromeBRCA2 SyndromeLynch Syndrome
Rabin Medical Center 200
Not applicableLooking for participantsNCT05420064
What this trial is testing

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Who this might be right for
BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more
Memorial Sloan Kettering Cancer Center 1,000
Not applicableActive Not RecruitingNCT04009148
What this trial is testing

Cascade Testing in Families With Newly Diagnosed Hereditary Breast and Ovarian Cancer Syndrome

Who this might be right for
BRCA-Mutated Ovarian CarcinomaBRIP1 Gene MutationMSH2 A636P+5 more
NYU Langone Health 118
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Not applicableUnknownNCT06163365
What this trial is testing

Inherited Cancer Early Diagnosis (ICED) Study

Who this might be right for
Li Fraumeni SyndromeLynch SyndromeHereditary Diffuse Gastric Cancer+5 more
Royal Marsden NHS Foundation Trust 100
Not applicableLooking for participantsNCT02775461
What this trial is testing

Pancreas Registry and High Risk Registry

Who this might be right for
Pancreas CancerPancreatitisChronic Pancreatitis+3 more
Icahn School of Medicine at Mount Sinai 1,368
Not applicableLooking for participantsNCT04095195
What this trial is testing

Registry of Subjects at Risk of Pancreatic Cancer

Who this might be right for
Familial Pancreatic CancerBRCA1 MutationBRCA2 Mutation+4 more
Associazione Italiana per lo Studio del Pancreas 1,000
Testing effectiveness (Phase 2)Ended earlyNCT03631641
What this trial is testing

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Who this might be right for
Colon AdenomaColon CarcinomaLynch Syndrome+2 more
John Hays 3
Not applicableStudy completedNCT01322165
What this trial is testing

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions

Who this might be right for
Marfan SyndromeTurner SyndromeEhlers-Danlos Syndrome+9 more
National Heart, Lung, and Blood Institute (NHLBI) 3,706
Not applicableLooking for participantsNCT07220239
What this trial is testing

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

Who this might be right for
Endometrial CancerLynch SyndromeScreening+1 more
Jessica D. St. Laurent, MD 25
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