Large-scale testing (Phase 3)Ended earlyNCT05632354What this trial is testingGBT021601-022: A Study of GBT021601 in Participants With Sickle Cell Disease (SCD)Who this might be right forSickle Cell Disease Pfizer 47
Not applicableWithdrawnNCT01374165What this trial is testingSafety and Pharmacokinetics of SANGUINATE™ in Sickle Cell Disease (SCD) PatientsWho this might be right forSickle Cell Disease Prolong Pharmaceuticals
Not applicableStudy completedNCT04584528What this trial is testingImplementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseGenetic DiseaseHematologic Diseases+1 more Duke University 279
Large-scale testing (Phase 3)Study completedNCT01175083What this trial is testingImmunization of Children Between 8 Weeks and 2 Years of Age With GSK Pneumococcal Vaccine GSK1024850AWho this might be right forInfections, Streptococcal GlaxoSmithKline 300
Testing effectiveness (Phase 2)Looking for participantsNCT05735717What this trial is testingMT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme MalignanciesWho this might be right forHematologic MalignancyAcute LeukemiaRemission+21 more Masonic Cancer Center, University of Minnesota 70
Early research (Phase 1)Study completedNCT02497924What this trial is testingThe Absorption, Metabolism, and Excretion of GBT440 in Healthy Male SubjectsWho this might be right forAnemia, Sickle Cell Global Blood Therapeutics 7
Not applicableUnknownNCT05105659What this trial is testingAssessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.Who this might be right forB Thalassemia Assiut University 60
Testing effectiveness (Phase 2)Study completedNCT01749540What this trial is testingStudy to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A536-04/MK-6143-002)Who this might be right forB-Thalassemia Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 64
Testing effectiveness (Phase 2)Study completedNCT01732718What this trial is testingEffect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseSickle Cell Nephropathy University of North Carolina, Chapel Hill 13
Testing effectiveness (Phase 2)Study completedNCT02961218What this trial is testingStudy of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell AnemiaWho this might be right forSickle Cell Anemia Novartis Pharmaceuticals 49
Early research (Phase 1)Looking for participantsNCT06647979What this trial is testingHematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-HemoglobinopathiesWho this might be right forSickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)Beta-Thalassemia+1 more Daniel Bauer 10
Testing effectiveness (Phase 2)Ended earlyNCT04474314What this trial is testingIMR-687 in Subjects With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Cardurion Pharmaceuticals, Inc. 115
Not applicableUnknownNCT04962984What this trial is testingThrombin Generation in Beta-thalassemia MajorWho this might be right forBeta Thalassemia Major Anemia Central Hospital, Nancy, France 45
Large-scale testing (Phase 3)Active Not RecruitingNCT04293185What this trial is testingA Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell DiseaseWho this might be right forSickle Cell Disease Genetix Biotherapeutics Inc. 35
Large-scale testing (Phase 3)Looking for participantsNCT06612268What this trial is testingEvaluate How Well Etavopivat Works in People With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Novo Nordisk A/S 510
Very early researchUnknownNCT03130517What this trial is testingEfficacy of Intravenous Immunoglobulin in Management of Rh and ABO Incompatibility DiseaseWho this might be right forHaemolysis Neonatal Assiut University 30
Not applicableLooking for participantsNCT06941389What this trial is testingComparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease (SCD) University of Rochester 480
Testing effectiveness (Phase 2)UnknownNCT03183375What this trial is testingThe Efficacy and Safety of HYDROXYUREA in Management of Beta Thalassemia Patients in Karachi PakistanWho this might be right forThalassemia, Beta Dr.Saqib Hussain Ansari 100
Not applicableLooking for participantsNCT06147414What this trial is testingDevelopment of Non-Invasive Prenatal Diagnosis for Single Gene DisordersWho this might be right forInvasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more Assistance Publique - Hôpitaux de Paris 550
Testing effectiveness (Phase 2)Ended earlyNCT00850993What this trial is testingA Safety and Efficacy Trial of Stannsoporfin in Neonates With HyperbilirubinemiaWho this might be right forHyperbilirubinemia, Neonatal InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company 58