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Results for “Haemophagocytic Lymphohistiocytosis”

114 trials

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Showing 20 of 114 results

Post-approval studies (Phase 4)Study completedNCT05744063
What this trial is testing

A Post-authorization Study to Describe the Safety and Efficacy of Emapalumab for the Treatment of pHLH in Treatment Experienced Chinese Patients

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 13
Not applicableEnded earlyNCT01547143
What this trial is testing

Pilot Study of Etoposide-based Therapy and Hematopoietic Cell Transplantation for Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Asan Medical Center 12
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Large-scale testing (Phase 3)UnknownNCT04120090
What this trial is testing

Ruxolitinib as a Salvage Therapy for Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 80
Testing effectiveness (Phase 2)UnknownNCT01818908
What this trial is testing

Trial of DA-EPOCH Regimen for NHL With HLH

Who this might be right for
NHL With Hemophagocytic Lymphohistiocytosis
The First Affiliated Hospital with Nanjing Medical University 50
Testing effectiveness (Phase 2)Looking for participantsNCT06160791
What this trial is testing

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytoses
Jerry Lee, MD, MSc, MPhil 36
Large-scale testing (Phase 3)Study completedNCT02069899
What this trial is testing

Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 58
Not applicableNot Yet RecruitingNCT06131489
What this trial is testing

Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement

Who this might be right for
Hemophagocytic LymphohistiocytosisEpstein-Barr VirusBowel Resection
Beijing Friendship Hospital 20
Large-scale testing (Phase 3)UnknownNCT02862054
What this trial is testing

Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown Etiology

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 30
Not applicableStudy completedNCT03510650
What this trial is testing

Diagnostic Biomarkers for Adult Hemophagocytic Lymphohistiocytosis in Critically Ill Patients (HEMICU)

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Charite University, Berlin, Germany 100
Testing effectiveness (Phase 2)Study completedNCT03513328
What this trial is testing

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeThalassemiaSickle Cell Disease+13 more
University of Florida 6
Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Large-scale testing (Phase 3)UnknownNCT04084626
What this trial is testing

PD1 Antibody and Lenalidomide as a Treatment for EBV-HLH or CAEBV

Who this might be right for
EBV Infection
Beijing Friendship Hospital 40
Large-scale testing (Phase 3)Study completedNCT03312751
What this trial is testing

Study to Assess the Efficacy and Safety of Emapalumab in Primary Haemophagocytic Lymphohistiocytosis

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06703216
What this trial is testing

Pre-emptive Anakinra for Cytokine Event Reduction

Who this might be right for
B-Acute Lymphoblastic LeukemiaCAR-T Cell TherapyCytokine Release Syndrome+2 more
Ann & Robert H Lurie Children's Hospital of Chicago 24
Not applicableUnknownNCT05677178
What this trial is testing

Response Prediction in EBV-HLH Using Metabonomics Analysis

Who this might be right for
Hemophagocytic LymphohistiocytosesEBVMetabonomics
Beijing Friendship Hospital 30
Testing effectiveness (Phase 2)WithdrawnNCT02007239
What this trial is testing

Tocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Children's Hospital of Philadelphia
Not applicableUnknownNCT05600959
What this trial is testing

Sensitivity and Specificity of Cytokines in the Diagnosis of Lymphoma-associated HLH

Who this might be right for
Hemophagocytic LymphohistiocytosesLymphoma
Beijing Friendship Hospital 60
Testing effectiveness (Phase 2)Ended earlyNCT04356690
What this trial is testing

Etoposide in Patients With COVID-19 Infection

Who this might be right for
COVID-19
Boston Medical Center 8
Not applicableLooking for participantsNCT05277272
What this trial is testing

INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytoses
Children's Hospital Medical Center, Cincinnati 200
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