Large-scale testing (Phase 3)UnknownNCT02912702What this trial is testingL-DEP as an Initial Treatment for EBV-HLHWho this might be right forHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 120
Testing effectiveness (Phase 2)UnknownNCT04405375What this trial is testingGPED Regimen for Relapsed/Refractory or Advanced ENKTCLWho this might be right forExtranodal NK/T-cell Lymphoma, Nasal Type Beijing Tongren Hospital 29
Testing effectiveness (Phase 2)Study completedNCT01104025What this trial is testingHybrid Immunotherapy for Hemophagocytic LymphoHistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Children's Hospital Medical Center, Cincinnati 31
Large-scale testing (Phase 3)UnknownNCT04084626What this trial is testingPD1 Antibody and Lenalidomide as a Treatment for EBV-HLH or CAEBVWho this might be right forEBV Infection Beijing Friendship Hospital 40
Not applicableUnknownNCT06491719What this trial is testingA Study on Efficacy and Safety of iNK Cells for CAEBV /EBV-HLH After Allo-HSCTWho this might be right forCAEBV (Chronic Active Epstein-Barr Virus Infection) SyndromeEBVHemophagocytic Lymphohistiocytoses Beijing Friendship Hospital 15
Testing effectiveness (Phase 2)Ended earlyNCT04356690What this trial is testingEtoposide in Patients With COVID-19 InfectionWho this might be right forCOVID-19 Boston Medical Center 8
Not applicableUnknownNCT05137522What this trial is testingChidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLHWho this might be right forChidamideHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 20
Not applicableUnknownNCT05532826What this trial is testingClinical Study of Donor EBV-CTL Infusion in Patients With CAEBV and EBV-HLH After Allo-HSCTWho this might be right forChronic Active Epstein-Barr Virus InfectionVirus-Associated Hemophagocytic Syndrome Beijing Friendship Hospital 15
Large-scale testing (Phase 3)Ended earlyNCT03985423What this trial is testingEvaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLHWho this might be right forHemophagocytic Lymphohistiocytoses Swedish Orphan Biovitrum 7
Large-scale testing (Phase 3)UnknownNCT04120090What this trial is testingRuxolitinib as a Salvage Therapy for Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 80
Not applicableStudy completedNCT06047210What this trial is testingEvaluation of IFNγ and Inflammatory Mediators in Patients With Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytoses Swedish Orphan Biovitrum 14
Not applicableLooking for participantsNCT05277272What this trial is testingINTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)Who this might be right forHemophagocytic Lymphohistiocytoses Children's Hospital Medical Center, Cincinnati 200
Post-approval studies (Phase 4)UnknownNCT04999878What this trial is testingA Prospective Clinical Study of Ruxolitinib and Etoposide Combined With DDGP Regimen (RUE-DDGP) in Induction Therapy of T/NK Cell Lymphoma-associated Hemophagocytic Syndrome.Who this might be right forHemophagocytic SyndromeT/NK-Cell Lymphoma Zhengzhou University 30
Not applicableActive Not RecruitingNCT03827343What this trial is testingRetrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With CancerWho this might be right forMacrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis National Cancer Institute (NCI) 500
Not applicableLooking for participantsNCT01793168What this trial is testingRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordWho this might be right forRare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more Sanford Health 20,000
Post-approval studies (Phase 4)Looking for participantsNCT07270835What this trial is testingZanubrutinib Combined With Rituximab in the Treatment of Secondary HLH in B-cell LymphomaWho this might be right forHemophagocytic LymphohistiocytosisB Cell Lymphoma The First Affiliated Hospital of Soochow University 40
Post-approval studies (Phase 4)Not Yet RecruitingNCT06504030What this trial is testingModified DEP Regimens for the Treatment of Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytoses The First Affiliated Hospital of Soochow University 20
Large-scale testing (Phase 3)UnknownNCT02862054What this trial is testingSplenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown EtiologyWho this might be right forHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 30
Not applicableNot Yet RecruitingNCT06131489What this trial is testingSegmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal InvolvementWho this might be right forHemophagocytic LymphohistiocytosisEpstein-Barr VirusBowel Resection Beijing Friendship Hospital 20
Not applicableLooking for participantsNCT05898477What this trial is testingDescribing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic LymphohistiocytosisWho this might be right forLymphomaHemophagocytic Lymphohistiocytoses University of Alabama at Birmingham 2,000