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Results for “Hamartoma Syndrome, Multiple”

138 trials

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Showing 20 of 138 results

Testing effectiveness (Phase 2)Looking for participantsNCT05104983
What this trial is testing

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

Who this might be right for
Tuberous Sclerosis ComplexEpilepsy
Darcy Krueger 64
Not applicableNo Longer AvailableNCT03317366
What this trial is testing

Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies

Who this might be right for
Proteus SyndromePIK3CA-Related Overgrowth Spectrum (PROS)Growth Disorders
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)
Not applicableStudy completedNCT02325505
What this trial is testing

Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma

Who this might be right for
Tuberous SclerosisLymphangioleiomyomatosisAngiomyolipoma
InCor Heart Institute 200
Large-scale testing (Phase 3)UnknownNCT01730209
What this trial is testing

Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex

Who this might be right for
Tuberous Sclerosis ComplexTSC Related Cognitive DisabilityTSC Related Autism+1 more
Erasmus Medical Center 60
Post-approval studies (Phase 4)Study completedNCT03525834
What this trial is testing

Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.

Who this might be right for
Renal Angiomyolipoma
Novartis Pharmaceuticals 40
Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
Not applicableLooking for participantsNCT05676099
What this trial is testing

TSC Biosample Repository and Natural History Database

Who this might be right for
Tuberous SclerosisLymphangioleiomyomatosis
National Tuberous Sclerosis Association 5,000
Large-scale testing (Phase 3)Study completedNCT02544763
What this trial is testing

Controlled Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)

Who this might be right for
Tuberous Sclerosis ComplexSeizures
Jazz Pharmaceuticals 224
Testing effectiveness (Phase 2)Study completedNCT05626634
What this trial is testing

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Who this might be right for
Developmental and Epileptic EncephalopathyDravet SyndromeLennox-Gastaut Syndrome
Longboard Pharmaceuticals 41
Not applicableEnrolling By InvitationNCT06330324
What this trial is testing

Reproductive Options in Inherited Skin Diseases

Who this might be right for
IchthyosisPalmoplantar KeratosesEpidermolysis Bullosa+7 more
Maastricht University Medical Center 650
Not applicableStudy completedNCT01780441
What this trial is testing

Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC)

Who this might be right for
Tuberous Sclerosis Complex
Boston Children's Hospital 166
Large-scale testing (Phase 3)Study completedNCT00790400
What this trial is testing

Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

Who this might be right for
Tuberous Sclerosis Complex (TSC)Lymphangioleiomyomatosis (LAM)
Novartis Pharmaceuticals 118
Large-scale testing (Phase 3)Study completedNCT05323734
What this trial is testing

Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy

Who this might be right for
Tuberous Sclerosis Complex
Marinus Pharmaceuticals 129
Testing effectiveness (Phase 2)WithdrawnNCT01690871
What this trial is testing

A Phase II Study of Orally Administered BEZ235 Monotherapy in Patients With Metastatic or Unresectable Malignant PEComa

Who this might be right for
Malignant PEComa (Perivascular Epithelioid Cell Tumors)
Novartis Pharmaceuticals
Large-scale testing (Phase 3)Ended earlyNCT05604170
What this trial is testing

Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy

Who this might be right for
Tuberous Sclerosis Complex
Marinus Pharmaceuticals 117
Not applicableLooking for participantsNCT00001975
What this trial is testing

Study of Skin Tumors in Tuberous Sclerosis

Who this might be right for
Tuberous Sclerosis
National Heart, Lung, and Blood Institute (NHLBI) 400
Not applicableLooking for participantsNCT06712095
What this trial is testing

Video Capsule Examination in Patients With Lynch Syndrome

Who this might be right for
Lynch SyndromeLi Fraumeni SyndromePTEN Hamartoma Syndrome+7 more
Royal Marsden NHS Foundation Trust 25
Large-scale testing (Phase 3)Looking for participantsNCT05534672
What this trial is testing

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex

Who this might be right for
Tuberous Sclerosis Complex
Katarzyna Kotulska 200
Large-scale testing (Phase 3)Study completedNCT03826628
What this trial is testing

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Who this might be right for
Facial AngiofibromaTuberous Sclerosis
Dermatology Specialties Limited Partnership 107
Not applicableUnknownNCT03326765
What this trial is testing

Characterizing Sleep Disorders in Children and Adults With Tuberous Sclerosis Complex (TSC)

Who this might be right for
Sleep Disorder
Universitair Ziekenhuis Brussel 60
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