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Results for “Haploidentical Hematopoietic Stem Cell Transplant”

265 trials

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Showing 20 of 265 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07193420
What this trial is testing

Reduced Post-transplant Cyclophosphamide Dose in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation for Hematological Malignancies

Who this might be right for
GVHD - Graft-Versus-Host DiseaseHSCTHaploidentical Stem Cell Transplantation
Assistance Publique - Hôpitaux de Paris 180
Testing effectiveness (Phase 2)Study completedNCT02500550
What this trial is testing

Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome
Kiadis Pharma 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04262843
What this trial is testing

Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaHigh Risk Myelodysplastic Syndrome+1 more
City of Hope Medical Center 33
Early research (Phase 1)Study completedNCT00569283
What this trial is testing

Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant

Who this might be right for
Cancer
Asan Medical Center 18
Testing effectiveness (Phase 2)Looking for participantsNCT04339777
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Who this might be right for
Lymphoproliferative DisordersAutoimmune LymphoproliferativeImmune System Diseases+2 more
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Looking for participantsNCT04414046
What this trial is testing

TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children

Who this might be right for
Primary Immune Deficiency DisordersMetabolic Disease
Johns Hopkins All Children's Hospital 17
Post-approval studies (Phase 4)Study completedNCT01883180
What this trial is testing

ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis

Who this might be right for
Hematopoietic Stem Cell TransplantationAntithymocyte GlobulinViral Infection
Nanfang Hospital, Southern Medical University 412
Not applicableStudy completedNCT04838704
What this trial is testing

Ruxolitinib With Calcineurin Inhibitor and Methotrexate vs. Calcineurin Inhibitor Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation

Who this might be right for
Graft Versus Host Disease
Zhejiang University 215
Early research (Phase 1)Study completedNCT02167958
What this trial is testing

Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source

Who this might be right for
LeukemiaMDSMyelofibrosis+1 more
Rafic Farah, MD 28
Testing effectiveness (Phase 2)Study completedNCT00993486
What this trial is testing

Dose-ranging Study of a Single Administration of T-cell Add-back Depleted of Host Alloreactive Cells in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor

Who this might be right for
Hematologic DiseasesHematologic Malignancies
Kiadis Pharma 19
Large-scale testing (Phase 3)Study completedNCT05166967
What this trial is testing

Targeted Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation

Who this might be right for
Haploidentical Hematopoietic Stem Cell Transplantation
Chinese PLA General Hospital 204
Testing effectiveness (Phase 2)UnknownNCT01374841
What this trial is testing

Hematopoietic Cell Transplantation for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors

Who this might be right for
Hematologic Neoplasms
European Institute of Oncology 20
Large-scale testing (Phase 3)Ended earlyNCT02999854
What this trial is testing

Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome
Kiadis Pharma 63
Testing effectiveness (Phase 2)Looking for participantsNCT04237623
What this trial is testing

GM-CSF With Post-Transplant Cyclophosphamide

Who this might be right for
Transplant-Related Hematologic Malignancy
Northside Hospital, Inc. 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT05621759
What this trial is testing

Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHD

Who this might be right for
Graft Vs Host Disease
NYU Langone Health 27
Testing effectiveness (Phase 2)Active Not RecruitingNCT05907746
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency

Who this might be right for
GATA2Immunodeficiency
National Institutes of Health Clinical Center (CC) 13
Not applicableEnded earlyNCT01350232
What this trial is testing

Treatment of Sickle Cell Anemia With Stem Cell Transplant

Who this might be right for
Sickle Cell AnemiaSickle Cell-hemoglobin C DiseaseSickle Cell-β0-thalassemia
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 2
Testing effectiveness (Phase 2)Ended earlyNCT02477787
What this trial is testing

Randomized Study of Haploidentical Hct and Subsequent Donor nk Cell Infusion in High-risk AML and MDS

Who this might be right for
Acute Myelogenous Leukemia
Asan Medical Center 77
Testing effectiveness (Phase 2)Ended earlyNCT02259348
What this trial is testing

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Who this might be right for
Acute Lymphoblastic Leukemia (ALL)Acute Myeloid Leukemia (AML)Myeloid Sarcoma+4 more
St. Jude Children's Research Hospital 12
Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
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