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Results for “Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)”

224 trials

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Showing 20 of 224 results

Testing effectiveness (Phase 2)WithdrawnNCT05312021
What this trial is testing

Selective PDE9 Inhibition With IMR-687 in Adults With Heart Failure With Preserved Ejection Fraction

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Cardurion Pharmaceuticals, Inc.
Not applicableNot Yet RecruitingNCT06655532
What this trial is testing

Effects of an Exercise Program in Women Over 60 yr. With HFpEF and Sarcopenia on Functional Capacity and Quality of Life

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFpEF)SarcopeniaWomen
Fundación para la Investigación del Hospital Clínico de Valencia 40
Not applicableNot Yet RecruitingNCT07324772
What this trial is testing

PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF

Who this might be right for
Atrial Fibrillation (AF)Atrial Fibrillation (Paroxysmal)Persistent Atrial Fibrillation+1 more
Northwestern University 30
Large-scale testing (Phase 3)Looking for participantsNCT07288398
What this trial is testing

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

Who this might be right for
Pulmonary Hypertension Associated With HFpEF
Tenax Therapeutics, Inc. 540
Testing effectiveness (Phase 2)Study completedNCT00839228
What this trial is testing

Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrome

Who this might be right for
Diastolic Heart Failure
University of Aberdeen 70
Testing effectiveness (Phase 2)Study completedNCT06731738
What this trial is testing

Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients.

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFPEF)
IC TARGETS AS 44
Testing effectiveness (Phase 2)Study completedNCT04945460
What this trial is testing

Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16)

Who this might be right for
Hypertension, Pulmonary
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA 164
Early research (Phase 1)Study completedNCT03843060
What this trial is testing

Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFpEF)
AstraZeneca 14
Testing effectiveness (Phase 2)Study completedNCT03015402
What this trial is testing

Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction

Who this might be right for
Pulmonary Hypertension SecondaryHeart Failure
University of Pittsburgh 33
Not applicableUnknownNCT04269057
What this trial is testing

Change of NLRP3 Inflammasome Expression Level, Symptoms, and Functional Status in HFpEF Patients Treated With ARNI

Who this might be right for
Heart Failure
Chongqing Medical University 90
Not applicableLooking for participantsNCT04587648
What this trial is testing

Cardiac Amyloidosis in HFpEF

Who this might be right for
Heart Failure With Preserved Ejection FractionAmyloidosis Cardiac
National Taiwan University Hospital 250
Large-scale testing (Phase 3)Study completedNCT03057951
What this trial is testing

EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)

Who this might be right for
Heart Failure
Boehringer Ingelheim 5,988
Not applicableStudy completedNCT06036186
What this trial is testing

Study for the Treatment of Heart Failure With Preserved Ejection Fraction Associated With High Blood Pressure Using Right Atrial Pacing Controlled by the PressurePaceTM System

Who this might be right for
Heart Failure With Preserved Ejection Fraction (HFpEF)Hypertension
BaroPace Inc. 16
Post-approval studies (Phase 4)UnknownNCT04739215
What this trial is testing

Effects of SGLT2 Inhibition on the Mechanisms of Cardiac Damage in the Diabetic Patient With HFpEF

Who this might be right for
Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection Fraction
Hospital General Universitario Gregorio Marañon 62
Not applicableLooking for participantsNCT07385417
What this trial is testing

Electroporation Treatment for Early AF Management in Heart Failure With Preserved Ejection Fraction (HFpEF) Pilot Study

Who this might be right for
Atrial Fibrillation (AF)
Cardioangiologisches Centrum Bethanien 200
Testing effectiveness (Phase 2)Study completedNCT03611153
What this trial is testing

Myeloperoxidase (MPO) Inhibitor A_Zeneca for Heart Failure With Preserved Ejection Fraction (HFpEF)

Who this might be right for
Heart Failure
Mayo Clinic 30
Not applicableUnknownNCT05731466
What this trial is testing

Exercise Right Ventricular Coupling in HFpEF

Who this might be right for
Heart Failure With Preserved Ejection FractionPulmonary Hypertension
Universitaire Ziekenhuizen KU Leuven 30
Large-scale testing (Phase 3)UnknownNCT06080802
What this trial is testing

The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction

Who this might be right for
Heart Failure With Preserved Ejection FractionDiabete Type 2
October University for Modern Sciences and Arts 80
Post-approval studies (Phase 4)Study completedNCT04767061
What this trial is testing

Impact of Beta-blockers on Physical Function in HFpEF

Who this might be right for
Heart FailureHeart Failure, DiastolicHeart Failure With Preserved Ejection Fraction+2 more
Weill Medical College of Cornell University 9
Not applicableStudy completedNCT01505179
What this trial is testing

The Effects of Ranolazine on Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction

Who this might be right for
Heart Failure With Preserved Ejection Fraction
University of California, San Diego 10
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