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Results for “Hemoglobin H Disease”

28 trials

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Showing 20 of 28 results

Not applicableLooking for participantsNCT05797272
What this trial is testing

In-utero Hematopoietic Stem Cell Transplantation for the Treatment of Fetuses With Bart's Hydrops Fetalis Syndrome

Who this might be right for
Haemoglobin Barts Hydrops
Chinese University of Hong Kong 10
Not applicableActive Not RecruitingNCT02692872
What this trial is testing

Screening for Alpha Thalassemia in Healthy Volunteers

Who this might be right for
Alpha Thalassemia
National Institute of Allergy and Infectious Diseases (NIAID) 367
Not applicableStudy completedNCT00159029
What this trial is testing

Genetics of Alpha Thalassemia in Israeli Ethnic Groups

Who this might be right for
Alpha Thalassemia
Deborah Rund 100
Not applicableEnrolling By InvitationNCT05528796
What this trial is testing

Uncovering the Etiologies of Non-immune Hydrops Fetalis

Who this might be right for
Non-Immune Hydrops Fetalis
University of California, San Francisco 500
Early research (Phase 1)Ended earlyNCT02986698
What this trial is testing

In Utero Hematopoietic Stem Cell Transplantation for Alpha-thalassemia Major (ATM)

Who this might be right for
Alpha Thalassemia MajorHemoglobinopathy; With ThalassemiaHemoglobinopathies+6 more
University of California, San Francisco 6
Testing effectiveness (Phase 2)Looking for participantsNCT05664737
What this trial is testing

Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia

Who this might be right for
Anemia
Bristol-Myers Squibb 189
Testing effectiveness (Phase 2)WithdrawnNCT01419704
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Who this might be right for
Anemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more
Talaris Therapeutics Inc.
Not applicableStudy completedNCT00971984
What this trial is testing

Demographic, Clinical and Laboratory Characteristics of Children With Alpha Thalassemia in Northern Israel

Who this might be right for
Thalassemia AlphaHemolytic Anemia
HaEmek Medical Center, Israel 50
Large-scale testing (Phase 3)Active Not RecruitingNCT04770779
What this trial is testing

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

Who this might be right for
Transfusion-dependent Alpha-ThalassemiaTransfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 258
Not applicableLooking for participantsNCT06591936
What this trial is testing

Genetic Profile of Alpha Thalassemia Children at Sohag University Hospital .

Who this might be right for
Alpha-Thalassemia
Sohag University 50
Not applicableStudy completedNCT04308603
What this trial is testing

Multicentric Prospective Study to Screen Inborn Errors of Metabolism in Non-immune Hydrops (NIH) Fetalis by Massively Parallel Sequencing

Who this might be right for
Non-Immune Hydrops Fetalis
Hospices Civils de Lyon 71
Not applicableUnknownNCT02956564
What this trial is testing

Precision Medical Research of Non-immune Fetal Hydrops (NIFH)-From Prenatal Diagnosis to Intrauterine Treatment

Who this might be right for
Fetal Hydrops
Shanghai First Maternity and Infant Hospital 144
Not applicableLooking for participantsNCT04872179
What this trial is testing

International Registry of Patients With Alpha Thalassemia

Who this might be right for
Alpha-ThalassemiaAlpha Thalassemia MajorAlpha Thalassemia Minor
University of California, San Francisco 500
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Testing effectiveness (Phase 2)Study completedNCT04987489
What this trial is testing

Etavopivat in Patients With Thalassemia or Sickle Cell Disease

Who this might be right for
Sickle Cell DiseaseThalassemia
Forma Therapeutics, Inc. 53
Not applicableStudy completedNCT06831799
What this trial is testing

ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19

Who this might be right for
HemoglobinopathiesSickle Cell DiseaseSickle Cell Anemia+21 more
Hospital Universitari Vall d'Hebron Research Institute 684
Large-scale testing (Phase 3)Not Yet RecruitingNCT07517133
What this trial is testing

Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With α- or β-Non-Transfusion-Dependent Thalassemia

Who this might be right for
Non-Transfusion-dependent Alpha-ThalassemiaNon-Transfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc. 45
Not applicableLooking for participantsNCT05799118
What this trial is testing

Study of the Role of Genetic Modifiers in Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseThalassemia, BetaThalassemia Alpha+1 more
Cyprus Institute of Neurology and Genetics 30,000
Testing effectiveness (Phase 2)Study completedNCT00873041
What this trial is testing

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study

Who this might be right for
Non-transfusion Dependent Thalassemia
Novartis Pharmaceuticals 166
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