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Results for “Hemolytic-uremic Syndrome”

77 trials

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Showing 20 of 77 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04958265
What this trial is testing

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Hoffmann-La Roche 41
Not applicableStudy completedNCT01406288
What this trial is testing

Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4

Who this might be right for
Hemolytic-uremic SyndromeEscherichia Coli Infections
University Hospital, Bordeaux 9
Not applicableEnded earlyNCT02614898
What this trial is testing

Evaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and Treatment

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 67
Not applicableLooking for participantsNCT05805202
What this trial is testing

Functional Implications of Rare Gene Mutations in aHUS Open the Door to Personalized Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 112
Large-scale testing (Phase 3)Active Not RecruitingNCT04889430
What this trial is testing

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 34
Not applicableStudy completedNCT02134171
What this trial is testing

Early Predictive Factors of Cardiac and Cerebral Involvement in TMA

Who this might be right for
Thrombotic MicroangiopathiesThrombotic Thrombocytopenic Purpura
Assistance Publique - Hôpitaux de Paris 119
Post-approval studies (Phase 4)Looking for participantsNCT07308574
What this trial is testing

Post-Marketing Clinical Study of Ravulizumab in Participants With Clinical aHUS

Who this might be right for
aHUSAtypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 20
Large-scale testing (Phase 3)Study completedNCT05876351
What this trial is testing

Eculizumab in Pediatric and Adult Participants With Atypical Hemolytic Uremic Syndrome (aHUS) in China

Who this might be right for
Atypical Hemolytic Uremic
Alexion Pharmaceuticals, Inc. 25
Testing effectiveness (Phase 2)Ended earlyNCT02464891
What this trial is testing

Complement Inhibition in aHUS Dialysis Patients

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Mario Negri Institute for Pharmacological Research 6
Large-scale testing (Phase 3)Ended earlyNCT04132375
What this trial is testing

Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUS

Who this might be right for
Bloody DiarrheaSTEC, UnspecifiedHemolytic-Uremic Syndrome+1 more
Inmunova S.A. 11
Not applicableStudy completedNCT01770951
What this trial is testing

A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome (aHUS)
Alexion Pharmaceuticals, Inc. 30
Post-approval studies (Phase 4)Study completedNCT02574403
What this trial is testing

Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Nantes University Hospital 58
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 125
Not applicableUnknownNCT06098378
What this trial is testing

Study of Patients With Thrombotic Microangiopathy Associated With Mitomycin C, Treated or Not With Eculizumab

Who this might be right for
Thrombotic Microangiopathies
University Hospital, Strasbourg, France 30
Testing effectiveness (Phase 2)Study completedNCT00844545
What this trial is testing

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alexion Pharmaceuticals, Inc. 16
Not applicableActive Not RecruitingNCT05985122
What this trial is testing

New Analytic Tools for aHUS and C3G Diagnosis

Who this might be right for
Hemolytic-Uremic SyndromeMembranoproliferative GlomerulonephritisHealthy
Mario Negri Institute for Pharmacological Research 180
Not applicableUnknownNCT03690024
What this trial is testing

Outcame of Cases With Hemolytic Uremic Syndrome Attending Assiut University Child Hospital

Who this might be right for
Hemolytic Uremic Syndrome of Childhood
Assiut University 50
Not applicableUnknownNCT03605511
What this trial is testing

TTP and aHUS in Complicated Pregnancies

Who this might be right for
Thrombotic Thrombocytopenic PurpuraAtypical Hemolytic Uremic SyndromePre-Eclampsia+5 more
University College, London 150
Testing effectiveness (Phase 2)Study completedNCT01194973
What this trial is testing

An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome

Who this might be right for
Atypical Hemolytic-Uremic Syndrome
Alexion Pharmaceuticals, Inc. 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05684159
What this trial is testing

Study of NM8074 in Patients With aHUS With Evidence of Ongoing Thrombotic Microangiopathy

Who this might be right for
aHUS - Atypical Hemolytic Uremic Syndrome
NovelMed Therapeutics 12
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