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Results for “Hemophagocytic Lymphohistiocytosis (HLH)”

119 trials

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Showing 20 of 119 results

Not applicableUnknownNCT04500886
What this trial is testing

Evaluate the Efficacy and Safety of PEG-rhG-CSF in Patients With Hemophagocytic Syndrome

Who this might be right for
Hemophagocytic Syndrome
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 50
Very early researchUnknownNCT05353179
What this trial is testing

Study on Pharmacokinetics of Meperizumab Injection and NUCALA® in Healthy Male Volunteers

Who this might be right for
Granulomatosis With PolyangiitisHemophagocytic Syndrome
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 88
Testing effectiveness (Phase 2)Study completedNCT02472054
What this trial is testing

Treatment of Familiar Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis (HLH)
Assistance Publique - Hôpitaux de Paris 29
Large-scale testing (Phase 3)UnknownNCT04077905
What this trial is testing

Pegylated Liposomal Doxorubicin as a Induction Therapy for Lymphoma Induced Hemophagocytic Lymphohistiocytosis.

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 160
Not applicableStudy completedNCT05531721
What this trial is testing

HLH Patients - a Retrospective Study

Who this might be right for
Hemophagocytic Lymphohistiocytoses
Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna 39
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06736080
What this trial is testing

Safety and Efficacy of Gene Therapy of FHL Type 3 Caused by Mutations in the Human UNC13D Gene by Transplantation of a Single Dose of Autologous CD34+ Cells Transduced ex Vivo With the UNC13D LV Vector Expressing the UNC13D cDNA

Who this might be right for
Familial Hemophagocytic Lymphohistiocytosis Type 3 (FHL 3)
Assistance Publique - Hôpitaux de Paris 5
Not applicableUnknownNCT05841342
What this trial is testing

Prospective Study of Immune Function and PD-1 Antibody Therapy Efficacy Predictors on CAEBV and EBV-HLH Patients

Who this might be right for
Secondary Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus Infection
Beijing Friendship Hospital 128
Not applicableEnded earlyNCT00006054
What this trial is testing

Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies

Who this might be right for
Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable Immunodeficiency+11 more
Fairview University Medical Center
Early research (Phase 1)UnknownNCT05546060
What this trial is testing

Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 20
Early research (Phase 1)Active Not RecruitingNCT01494103
What this trial is testing

Administration of Donor T Cells With the Caspase-9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaMyelodysplastic SyndromeAcute Myeloid Leukemia+7 more
Baylor College of Medicine 15
Testing effectiveness (Phase 2)UnknownNCT06244862
What this trial is testing

JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care Unit

Who this might be right for
Hemophagocytic Syndromes
Assistance Publique - Hôpitaux de Paris 42
Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
Large-scale testing (Phase 3)Study completedNCT05001737
What this trial is testing

Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

Who this might be right for
Macrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more
Swedish Orphan Biovitrum 33
Not applicableLooking for participantsNCT03491605
What this trial is testing

Surveillance and Tracking the Outcomes of Chronic Latent EBV Infection

Who this might be right for
EBV Infection
Huazhong University of Science and Technology 10,000
Testing effectiveness (Phase 2)Looking for participantsNCT07525466
What this trial is testing

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Who this might be right for
Extranodal NK T Cell LymphomaHemophagocytic Lymphohistiocytosis (HLH)
Beijing Tongren Hospital 25
Not applicableUnknownNCT00006056
What this trial is testing

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Who this might be right for
Chediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more
Fairview University Medical Center 40
Testing effectiveness (Phase 2)Study completedNCT01998633
What this trial is testing

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Who this might be right for
Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus InfectionChronic Granulomatous Disease+3 more
Medical College of Wisconsin 47
Not applicableNot Yet RecruitingNCT07741747
What this trial is testing

Impact of Ultra-fast Genetic Diagnosis of Familial Lymphohistiocytosis on the Time to Bone Marrow Transplantation and Overall Survival

Who this might be right for
Familial LymphohistiocytosisLymphohistiocytosis
Assistance Publique Hopitaux De Marseille 240
Not applicableStudy completedNCT03259230
What this trial is testing

Evaluation of IFNγ and Inflammatory Mediators in Patients With Malignancy-Associated Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 40
Testing effectiveness (Phase 2)Study completedNCT00368355
What this trial is testing

T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts

Who this might be right for
Acute Lymphoblastic LeukemiaNon Hodgkins LymphomaMyelodysplastic Syndrome+6 more
Baylor College of Medicine 46
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