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Results for “Hepatocellular Carcinoma by AJCC Stage”

51 trials

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Showing 20 of 51 results

Not applicableStudy completedNCT05059665
What this trial is testing

Performance Evaluation (Sensitivity/Specificity) of HelioLiver Test for Detection of HCC

Who this might be right for
Hepatocellular Carcinoma by AJCC Stage
Helio Genomics 290
Not applicableActive Not RecruitingNCT05038254
What this trial is testing

Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events

Who this might be right for
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+42 more
M.D. Anderson Cancer Center 750
Testing effectiveness (Phase 2)Looking for participantsNCT07042919
What this trial is testing

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

Who this might be right for
Advanced Hepatocellular CarcinomaCirrhosisStage III Hepatocellular Carcinoma AJCC v8+1 more
Devalingam Mahalingam 59
Testing effectiveness (Phase 2)Active Not RecruitingNCT05194293
What this trial is testing

Regorafenib and Durvalumab for the Treatment of High-Risk Liver Cancer

Who this might be right for
Stage IB Hepatocellular Carcinoma AJCC v8Stage II Hepatocellular Carcinoma AJCC v8Stage III Hepatocellular Carcinoma AJCC v8+1 more
Academic and Community Cancer Research United 4
Testing effectiveness (Phase 2)Study completedNCT03439891
What this trial is testing

Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v7+4 more
Robin Kate Kelley 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07836712
What this trial is testing

Multiple Adjunct Therapies to Improve Immunotherapy Treatment in Patients With Locally Advanced or Metastatic Melanoma or Advanced Hepatocellular Cancer

Who this might be right for
Advanced Hepatocellular CarcinomaAdvanced MelanomaLocally Advanced Melanoma+3 more
University of Southern California 46
Not applicableActive Not RecruitingNCT03896646
What this trial is testing

Radioembolization for HCC Patients With Personalized Yttrium-90 Dosimetry for Curative Intent (RAPY90D)

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 42
Early research (Phase 1)Study completedNCT02143401
What this trial is testing

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
CirrhosisHepatitis B InfectionHepatitis C Infection+6 more
National Cancer Institute (NCI) 29
Testing effectiveness (Phase 2)Ended earlyNCT04785287
What this trial is testing

Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies

Who this might be right for
Advanced Lung CarcinomaAdvanced Malignant Solid NeoplasmMalignant Adrenal Gland Neoplasm+14 more
M.D. Anderson Cancer Center 13
Testing effectiveness (Phase 2)Looking for participantsNCT06265285
What this trial is testing

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Who this might be right for
Advanced Esophageal Squamous Cell CarcinomaAdvanced Renal Cell CarcinomaClinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8+28 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Looking for participantsNCT06811116
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+1 more
National Cancer Institute (NCI) 92
Large-scale testing (Phase 3)Looking for participantsNCT07166406
What this trial is testing

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

Who this might be right for
Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8
NRG Oncology 226
Early research (Phase 1)Active Not RecruitingNCT03655002
What this trial is testing

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

Who this might be right for
Recurrent Hepatocellular CarcinomaRefractory Liver CarcinomaStage IV Hepatocellular Carcinoma AJCC v8+2 more
City of Hope Medical Center 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07511504
What this trial is testing

Y-90 Radioembolization, Durvalumab, Tremelimumab, and Zanzalintinib for the Treatment of Unresectable and Locally-Advanced Hepatocellular Carcinoma

Who this might be right for
Locally Advanced Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+1 more
OHSU Knight Cancer Institute 40
Testing effectiveness (Phase 2)Looking for participantsNCT05168163
What this trial is testing

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Who this might be right for
Locally Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8+6 more
Academic and Community Cancer Research United 122
Not applicableLooking for participantsNCT06349642
What this trial is testing

Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

Who this might be right for
Early Stage Triple-Negative Breast CarcinomaMetastatic Bladder Urothelial CarcinomaMetastatic Cervical Carcinoma+24 more
Mayo Clinic 324
Testing effectiveness (Phase 2)Looking for participantsNCT04380545
What this trial is testing

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage IIIA Hepatocellular Carcinoma AJCC v8Stage IIIB Hepatocellular Carcinoma AJCC v8+4 more
M.D. Anderson Cancer Center 15
Testing effectiveness (Phase 2)Looking for participantsNCT03942328
What this trial is testing

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+3 more
Mayo Clinic
Early research (Phase 1)Temporarily pausedNCT06968195
What this trial is testing

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaRecurrent Hepatocellular Carcinoma+3 more
Roswell Park Cancer Institute 24
Early research (Phase 1)Study completedNCT02595866
What this trial is testing

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

Who this might be right for
AIDS-Related Non-Hodgkin LymphomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+16 more
National Cancer Institute (NCI) 58
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