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Results for “Hereditary Breast/Ovarian Cancer - BRCA1”

45 trials

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Showing 20 of 45 results

Not applicableEnded earlyNCT04668521
What this trial is testing

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

Who this might be right for
Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more
Aspira Women's Health 215
Testing effectiveness (Phase 2)Ended earlyNCT02203513
What this trial is testing

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Who this might be right for
Ovarian CancerBreast CancerProstate Cancer
National Cancer Institute (NCI) 111
Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
Large-scale testing (Phase 3)Study completedNCT00685256
What this trial is testing

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
Georgetown University 245
Not applicableNot Yet RecruitingNCT07236359
What this trial is testing

Evaluation of Well Being and Patient Reported Outcomes After Robotic Single-port Nipple Sparing Mastectomy and Implant Reconstruction

Who this might be right for
Breast ReconstructionBreast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)+1 more
Beaumont Hospital 108
Early research (Phase 1)Study completedNCT01104259
What this trial is testing

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerHereditary Breast/Ovarian Cancer - BRCA1+6 more
University of Washington 50
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Not applicableUnknownNCT00855998
What this trial is testing

Thymidine Kinase 1 in Risk Assessment for Hereditary Breast /Ovarian Cancer

Who this might be right for
Breast CancerOvarian Cancer
Hadassah Medical Organization 300
Not applicableLooking for participantsNCT07532434
What this trial is testing

A Bidirectional Cohort Study on Prophylactic Resection Surgery in Populations at Moderate-to-High Risk for Hereditary Ovarian Cancer

Who this might be right for
Ovarian CancerBreast Cancer
Peking University Third Hospital 480
Not applicableStudy completedNCT02451735
What this trial is testing

Genetic Counseling for Breast Cancer Survivors (GC for BC)

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 157
Not applicableStudy completedNCT06534424
What this trial is testing

Clinical Impact of Enhanced Risk Assessments in Women With a BRCA1/2 Mutation, CARE Study

Who this might be right for
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
Ohio State University Comprehensive Cancer Center 152
Not applicableStudy completedNCT00040222
What this trial is testing

Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

Who this might be right for
Familial Ovarian CancerFamilial Breast CancerBRCA1-associate Malignancies+1 more
National Cancer Institute (NCI) 377
Testing effectiveness (Phase 2)Study completedNCT00253539
What this trial is testing

Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
The Cleveland Clinic 3
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Not applicableLooking for participantsNCT04494945
What this trial is testing

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Who this might be right for
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer SyndromeBreast Ductal Carcinoma In SituHematopoietic and Lymphoid System Neoplasm+3 more
OHSU Knight Cancer Institute 27,500
Not applicableEnded earlyNCT01374685
What this trial is testing

Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans

Who this might be right for
Ovarian NeoplasmCancer GeneticsBreast Cancer
National Human Genome Research Institute (NHGRI) 8
Not applicableActive Not RecruitingNCT01230346
What this trial is testing

Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer

Who this might be right for
No Evidence of DiseaseBRCA1 SyndromeBRCA2 Syndrome+2 more
City of Hope Medical Center 493
Not applicableEnrolling By InvitationNCT07381985
What this trial is testing

Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment

Who this might be right for
Hereditary Cancer SyndromesBRCA1 Hereditary Breast and Ovarian Cancer SyndromeLynch Syndrome
University of Vermont Medical Center 200
Not applicableActive Not RecruitingNCT01608074
What this trial is testing

Radical Fimbriectomy for Young BRCA Mutation Carriers

Who this might be right for
BRCA1 MutationBRCA2 MutationHereditary Breast and Ovarian Cancer
Centre Oscar Lambret 123
Not applicableStudy completedNCT00001468
What this trial is testing

Outcomes of Education and Counseling for BRCA1 Testing

Who this might be right for
Breast NeoplasmsOvarian Neoplasms
National Human Genome Research Institute (NHGRI) 1,500
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