Crick — Clinical Intelligence Platform

Early research (Phase 1)Study completedNCT04601051

What this trial is testing

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Who this might be right for

Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis

Intellia Therapeutics 72

Results for “Hereditary Cardiac Amyloidosis”

Autonomic Evaluation of Patients With Hereditary Amyloidotic Cardiomyopathy: Hereditary Amyloidotic Heart Disease

TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects

Exercise Training and Rehabilitation In Cardiac Amyloidosis

Screening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker Implantation

Screening, Characterization, and Longitudinal Follow-up of Patients With Cardiac Amyloidosis

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Exercise Effect on Transthyretin Stability

Thalidomide/Dexamethasone Treatment And PET Evaluation In Organ Involvemenet of Cardiac Amyloidosis

Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

Screening for Amyloidosis Before Aortic Valve Elective Replacement

Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)

PET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 Levels

PET Imaging With [18F]Fluselenamyl in People With Cardiac Amyloidosis

Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis

Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy

DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research Studies

Retrospective Identification of Scintigraphic Cardiac Amyloidosis (RISCA)

New Biomarkers and Plasma Prothrombotic Potential in Cardiac Transthyretin Amyloidosis

Frontline Lenalidomide for AL Amyloidosis Involving Myocardium