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Results for “Hereditary Nonpolyposis Colon Cancer”

147 trials

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Showing 20 of 147 results

Testing effectiveness (Phase 2)Looking for participantsNCT04920149
What this trial is testing

Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome

Who this might be right for
Lynch SyndromeColon CancerColon Neoplasm
Ann-Sofie Backman 150
Early research (Phase 1)WithdrawnNCT04500548
What this trial is testing

Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study

Who this might be right for
Constitutional Mismatch Repair Deficiency SyndromeHematopoietic and Lymphoid Cell NeoplasmLynch Syndrome+9 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT02570516
What this trial is testing

NBI Versus Indigo Carmine During Colonoscopy in Lynch Syndrome

Who this might be right for
Lynch Syndrome
Assistance Publique - Hôpitaux de Paris 141
Testing effectiveness (Phase 2)Active Not RecruitingNCT02978625
What this trial is testing

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Who this might be right for
Anaplastic Large Cell Lymphoma, ALK-NegativeAnaplastic Large Cell Lymphoma, ALK-PositiveApocrine Carcinoma+36 more
National Cancer Institute (NCI) 68
Not applicableLooking for participantsNCT07220239
What this trial is testing

Menstrual Cup for Early Endometrial Cancer Detection in Lynch Syndrome

Who this might be right for
Endometrial CancerLynch SyndromeScreening+1 more
Jessica D. St. Laurent, MD 25
Early research (Phase 1)Looking for participantsNCT07163403
What this trial is testing

First in Human Pilot Study to Assess the Safety and Efficacy of Dendritic Cells Loaded With Frameshift Derived Neopeptides for the Prevention of Cancer in of Lynch Syndrome Carriers

Who this might be right for
Lynch Syndrome
Fundacion Clinic per a la Recerca Biomédica 20
Not applicableUnknownNCT00141466
What this trial is testing

Implementation of a New Strategy to Identify HNPCC Patients

Who this might be right for
Colorectal NeoplasmsHereditary Nonpolyposis Colorectal Cancer
Radboud University Medical Center 360
Not applicableLooking for participantsNCT05410977
What this trial is testing

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

Who this might be right for
Colorectal CarcinomaLynch Syndrome
Mayo Clinic 750
Not applicableLooking for participantsNCT07219537
What this trial is testing

Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

Who this might be right for
Lynch SyndromeCrohn DiseaseInflammatory Bowel Diseases+1 more
Massachusetts General Hospital 30
Not applicableLooking for participantsNCT03805919
What this trial is testing

Men at High Genetic Risk for Prostate Cancer

Who this might be right for
Prostatic Neoplasms
National Cancer Institute (NCI) 500
Not applicableLooking for participantsNCT05495776
What this trial is testing

Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerLynch SyndromeHereditary Colorectal Cancer+1 more
State Scientific Centre of Coloproctology, Russian Federation 2,500
Not applicableLooking for participantsNCT05704010
What this trial is testing

Videocapsule Endoscopy in Lynch Syndrome

Who this might be right for
Lynch SyndromeLynch Syndrome ILynch Syndrome II+5 more
San Raffaele University 100
Not applicableWithdrawnNCT04778566
What this trial is testing

Evaluating the Cologuard Test for Use in Lynch Syndrome

Who this might be right for
Lynch SyndromeColorectal CancerColonic Adenoma+1 more
Geisinger Clinic
Not applicableStudy completedNCT06426927
What this trial is testing

PeLear CCC: Proyecto Latino Contra Cancer Colorrectal

Who this might be right for
Colorectal CancerRectal CancerColon Cancer+4 more
University of North Carolina, Chapel Hill 60
Testing effectiveness (Phase 2)Ended earlyNCT03631641
What this trial is testing

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Who this might be right for
Colon AdenomaColon CarcinomaLynch Syndrome+2 more
John Hays 3
Large-scale testing (Phase 3)Not Yet RecruitingNCT02497820
What this trial is testing

Finding the Best Dose of Aspirin to Prevent Lynch Syndrome Cancers

Who this might be right for
Lynch Syndrome I (Site-specific Colonic Cancer)
Tel-Aviv Sourasky Medical Center 1,800
Not applicableLooking for participantsNCT02705846
What this trial is testing

Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations

Who this might be right for
Prostate Cancer
Institute of Cancer Research, United Kingdom 4,260
Not applicableActive Not RecruitingNCT02206360
What this trial is testing

Pancreatic Cancer Early Detection Program

Who this might be right for
Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+8 more
White Plains Hospital 100
Large-scale testing (Phase 3)Looking for participantsNCT02000089
What this trial is testing

The Cancer of the Pancreas Screening-5 CAPS5)Study

Who this might be right for
Pancreas CancerPeutz-Jeghers Syndrome (PJS)Gene Mutation+2 more
Johns Hopkins University 9,000
Not applicableStudy completedNCT01322165
What this trial is testing

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions

Who this might be right for
Marfan SyndromeTurner SyndromeEhlers-Danlos Syndrome+9 more
National Heart, Lung, and Blood Institute (NHLBI) 3,706
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