Not applicableActive Not RecruitingNCT05103943What this trial is testingAmyloidosis TTR Flow Reserve EvaluationWho this might be right forAmyloid Cardiomyopathy Centre Hospitalier Régional d'Orléans 50
Not applicableNot Yet RecruitingNCT07538518What this trial is testingPET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 LevelsWho this might be right forAmyloidogenic Transthyretin (ATTR) AmyloidosisCardiac Amyloidosis Lorena Saelices 25
Not applicableNot Yet RecruitingNCT07567508What this trial is testingEarly Detection of Concealed Cardiac Amyloidosis Using AI-ECG and CT-Derived Extracellular Volume in Patients With Atrial FibrillationWho this might be right forAtrial Fibrillation (AF)Cardiac Amyloidosis Samsung Medical Center 500
Very early researchStudy completedNCT03119558What this trial is testingPET/MRI Evaluation of Cardiac AmyloidWho this might be right forCardiac Amyloidosis Stanford University 9
Not applicableLooking for participantsNCT05489549What this trial is testingSubclinical Transthyretin Cardiac Amyloidosis in V122I TTR CarriersWho this might be right forAmyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more University of Texas Southwestern Medical Center 500
Not applicableLooking for participantsNCT07382128What this trial is testingMyocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy PhenotypesWho this might be right forHCM - Hypertrophic CardiomyopathyAnderson Fabry DiseaseCardiac Magnetic Resonance Imaging+1 more IRCCS Azienda Ospedaliero-Universitaria di Bologna 250
Not applicableLooking for participantsNCT06907836What this trial is testingDescription of a Retrospective Cohort of Patients With Transthyretin Cardiac Amyloidosis (ATTR-CA) in Internal MedicineWho this might be right forCardiac Amyloidosis University Hospital, Strasbourg, France 30
Post-approval studies (Phase 4)Looking for participantsNCT06940336What this trial is testingTo Evaluate the Efficacy and Safety of Tafamidis Meglumine Soft Capsules in the Treatment of Adult Patients With Transthyretin Amyloid PolyneuropathyWho this might be right forTransthyretin Amyloid Polyneuropathy Qilu Pharmaceutical Co., Ltd. 15
Not applicableLooking for participantsNCT06907186What this trial is testingAn Interventional Pilot Study to Investigate the Feasibility and Acceptance of a Structured Psychological Support Program for Patients, Caregivers, and Presymptomatic Carriers in Hereditary Transthyretin Amyloidosis With CardiomyopathyWho this might be right forHereditary Transthyretin Amyloidosis Fondazione IRCCS Policlinico San Matteo di Pavia 150
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473What this trial is testingTo Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)Who this might be right forAmyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more Eidos Therapeutics, a BridgeBio company 250
Not applicableStudy completedNCT01705626What this trial is testingScreening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP)Who this might be right forPolyneuropathy, AmyloidNeuropathic PainCardiac Failure+2 more CENTOGENE GmbH Rostock 500
Large-scale testing (Phase 3)Study completedNCT00294671What this trial is testingThe Effect of Diflunisal on Familial AmyloidosisWho this might be right forFamilial Amyloid PolyneuropathyFamilial Amyloidosis Boston University 130
Large-scale testing (Phase 3)Active Not RecruitingNCT04153149What this trial is testingHELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyWho this might be right forTransthyretin Amyloidosis (ATTR) With Cardiomyopathy Alnylam Pharmaceuticals 655
Large-scale testing (Phase 3)Study completedNCT01737398What this trial is testingEfficacy and Safety of Inotersen in Familial Amyloid PolyneuropathyWho this might be right forFAPFamilial Amyloid PolyneuropathyTTR+2 more Ionis Pharmaceuticals, Inc. 173
Not applicableUnknownNCT05699044What this trial is testingScreening of ATTRwt in Patient With Advanced AV-Block Undergoing Pacemaker ImplantationWho this might be right forAmyloid CardiomyopathyBlock, AV Steen Hvitfeldt Poulsen 170
Early research (Phase 1)Study completedNCT05374564What this trial is testingParametric Cardiac 18F-flutemetamol PET Imaging in ATTR CardiomyopathyWho this might be right forCardiomyopathies, Primary Yale University 12
Not applicableUnknownNCT04146415What this trial is testingDiagnosis of Cardiac Amyloidosis With 99mTc-PYP; Comparison Between Planar Imaging, SPECT/CT and Cardiac-dedicated CZT CameraWho this might be right forCardiac Amyloidosis Tel-Aviv Sourasky Medical Center 30
Very early researchLooking for participantsNCT06082050What this trial is testingEfficacy and Safety of Intravenous YOLT-201 for Transthyretin Amyloidosis CardiomyopathyWho this might be right forTransthyroxin Amyloidosis Cardiomyopathy Zhejiang University 7
Not applicableLooking for participantsNCT07654855What this trial is testingLong-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired SubpopulationsWho this might be right forTransthyretin AmyloidosisTransthyretin Amyloidosis With CardiomyopathyTransthyretin Amyloidosis With Polyneuropathy AstraZeneca 320
Not applicableUnknownNCT05754099What this trial is testingIdentification of Clinically Significant Markers of ATTRv in Pre-symptomatic Mutation Carriers.Who this might be right forAmyloidosis Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20