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Results for “Heterozygous Familial”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT00694109
What this trial is testing

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 144
Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Large-scale testing (Phase 3)Not Yet RecruitingNCT07450378
What this trial is testing

QLC7401 in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Qilu Pharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Study completedNCT01890967
What this trial is testing

LY3015014 in Participants With High Cholesterol

Who this might be right for
Hypercholesterolemia
Eli Lilly and Company 527
Large-scale testing (Phase 3)Study completedNCT00654446
What this trial is testing

IIIb 6 Week Open Label Multicentre Rosuvastatin & Simvastatin

Who this might be right for
Fredrickson Type IIa & Type IIb Dyslipidaemia
AstraZeneca 442
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Post-approval studies (Phase 4)Study completedNCT02957682
What this trial is testing

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 2,176
Large-scale testing (Phase 3)Study completedNCT00552097
What this trial is testing

Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)

Who this might be right for
AtherosclerosisHypercholesterolemiaHyperlipoproteinemia Type II
Organon and Co 720
Testing effectiveness (Phase 2)Study completedNCT02890992
What this trial is testing

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolaemia
Sanofi 42
Not applicableStudy completedNCT02976818
What this trial is testing

Lp(a) and Aortic Valve Calcification

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Laval University 173
Post-approval studies (Phase 4)Ended earlyNCT03694197
What this trial is testing

Long Term Safety Study of PRALUENT

Who this might be right for
Heterozygous Familial HypercholesterolemiaNon-familial Hypercholesterolemia
Regeneron Pharmaceuticals 1,389
Early research (Phase 1)Ended earlyNCT01583647
What this trial is testing

Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)

Who this might be right for
Hypercholesterolemia, FamilialHeterozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC 10
Large-scale testing (Phase 3)Looking for participantsNCT07465263
What this trial is testing

Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 135
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Large-scale testing (Phase 3)Not Yet RecruitingNCT07775339
What this trial is testing

Long-Term Efficacy and Safety of Lerodalcibep in Children and Adolescents With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
LIB Therapeutics LLC 150
Large-scale testing (Phase 3)Looking for participantsNCT06568471
What this trial is testing

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

Who this might be right for
HypercholesterolemiaDyslipidemiasPrimary Hypercholesterolemia+4 more
Hasten Biopharmaceutical Co., Ltd. 210
Large-scale testing (Phase 3)Study completedNCT01968980
What this trial is testing

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Pfizer 370
Not applicableUnknownNCT04837638
What this trial is testing

Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, FamilialCalcification; HeartDiet Habit
Laval University 258
Testing effectiveness (Phase 2)Study completedNCT05694260
What this trial is testing

A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Who this might be right for
Hypercholesterolemia
Esperion Therapeutics, Inc. 31
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