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Results for “Heterozygous Familial Hypercholesterolaemia”

91 trials

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Showing 20 of 91 results

Early research (Phase 1)Study completedNCT05398029
What this trial is testing

VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaAtherosclerotic Cardiovascular DiseaseHypercholesterolemia
Verve Therapeutics, Inc. 13
Large-scale testing (Phase 3)Study completedNCT00654602
What this trial is testing

48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety

Who this might be right for
Dyslipidaemia
AstraZeneca 1,500
Very early researchNot Yet RecruitingNCT07353398
What this trial is testing

Early-phase Study of ART002g1 Injection in HeFH: Safety, Tolerability and Preliminary Efficacy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 24
Not applicableUnknownNCT02517944
What this trial is testing

MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Institute of Cardiometabolism and Nutrition, France 110
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Early research (Phase 1)Looking for participantsNCT06164730
What this trial is testing

VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaPremature Coronary Heart Disease
Verve Therapeutics, Inc. 85
Testing effectiveness (Phase 2)Study completedNCT02890992
What this trial is testing

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolaemia
Sanofi 42
Not applicableStudy completedNCT03563547
What this trial is testing

Effects of Soy Protein on Cholesterol Levels in Children Affected With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Austrian Academic Institute for Clinical Nutrition 34
Large-scale testing (Phase 3)Active Not RecruitingNCT07000136
What this trial is testing

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH

Who this might be right for
Heterozygous Familial Hypercholesterolaemia
AstraZeneca 473
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Not applicableStudy completedNCT05181553
What this trial is testing

Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia.

Who this might be right for
Familial HypercholesterolemiaNutrition, HealthyCholesterol, Elevated+2 more
Laval University 50
Large-scale testing (Phase 3)Ended earlyNCT00384293
What this trial is testing

Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED)

Who this might be right for
Hypercholesterolemia, Familial
Merck Sharp & Dohme LLC 937
Testing effectiveness (Phase 2)Study completedNCT01266876
What this trial is testing

Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 77
Large-scale testing (Phase 3)Study completedNCT00552097
What this trial is testing

Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)

Who this might be right for
AtherosclerosisHypercholesterolemiaHyperlipoproteinemia Type II
Organon and Co 720
Large-scale testing (Phase 3)Study completedNCT03067441
What this trial is testing

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Disease
Esperion Therapeutics, Inc. 1,462
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Large-scale testing (Phase 3)Study completedNCT05425745
What this trial is testing

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+6 more
NewAmsterdam Pharma 354
Large-scale testing (Phase 3)Study completedNCT00694109
What this trial is testing

An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 144
Large-scale testing (Phase 3)Study completedNCT03510884
What this trial is testing

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolaemia
Sanofi 153
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