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Results for “Heterozygous Familial Hypercholesterolaemia”

93 trials

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Showing 20 of 93 results

Large-scale testing (Phase 3)Study completedNCT00129402
What this trial is testing

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Who this might be right for
Hypercholesterolemia
Organon and Co 248
Testing effectiveness (Phase 2)Study completedNCT03038022
What this trial is testing

Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Madrigal Pharmaceuticals, Inc. 116
Large-scale testing (Phase 3)Not Yet RecruitingNCT07775339
What this trial is testing

Long-Term Efficacy and Safety of Lerodalcibep in Children and Adolescents With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
LIB Therapeutics LLC 150
Large-scale testing (Phase 3)Study completedNCT00134485
What this trial is testing

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 400
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)Study completedNCT01475825
What this trial is testing

The Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol

Who this might be right for
HypercholesterolemiaHeterozygous Familial
Kastle Therapeutics, LLC 309
Not applicableStudy completedNCT06389825
What this trial is testing

Unravelling the Impact of Diet on Cardiovascular Health in Treated Heterozygous Familial Hypercholesterolemia.

Who this might be right for
Familial HypercholesterolemiaNutrition, HealthyCholesterol, Elevated
Laval University 11
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)Study completedNCT04666298
What this trial is testing

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 312
Testing effectiveness (Phase 2)Study completedNCT00477594
What this trial is testing

Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 21
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07839936
What this trial is testing

VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease

Who this might be right for
AtherosclerosisCardiovascular DiseaseHypercholesterolemia
Verve Therapeutics, Inc. 175
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Study completedNCT01824238
What this trial is testing

The Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 68
Not applicableLooking for participantsNCT07427472
What this trial is testing

"Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)"

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Assistance Publique - Hôpitaux de Paris 300
Large-scale testing (Phase 3)Study completedNCT00827606
What this trial is testing

Atorvastatin Three Year Pediatric Study

Who this might be right for
Familial Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 272
Large-scale testing (Phase 3)Study completedNCT01954394
What this trial is testing

Open Label Study of Long Term Safety Evaluation of Alirocumab

Who this might be right for
Hypercholesterolemia
Sanofi 986
Early research (Phase 1)Study completedNCT05398029
What this trial is testing

VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease

Who this might be right for
Heterozygous Familial HypercholesterolemiaAtherosclerotic Cardiovascular DiseaseHypercholesterolemia
Verve Therapeutics, Inc. 13
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Large-scale testing (Phase 3)Ended earlyNCT00151788
What this trial is testing

Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.

Who this might be right for
AtherosclerosisHeterozygous Familial Hypercholesterolemia
Daiichi Sankyo 796
Testing effectiveness (Phase 2)Study completedNCT05694260
What this trial is testing

A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Who this might be right for
Hypercholesterolemia
Esperion Therapeutics, Inc. 31
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