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Results for “Heterozygous Familial Hypercholesterolemia”

92 trials

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Showing 20 of 92 results

Not applicableUnknownNCT02517944
What this trial is testing

MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Institute of Cardiometabolism and Nutrition, France 110
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Not applicableEnrolling By InvitationNCT06112327
What this trial is testing

Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease

Who this might be right for
Atherosclerotic Cardiovascular DiseaseHeterozygous Familial HypercholesterolemiaHypercholesterolemia
Verve Therapeutics, Inc. 116
Testing effectiveness (Phase 2)Study completedNCT01515241
What this trial is testing

Exploratory Study of Plaque Regression

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Cerenis Therapeutics, SA 10
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)UnknownNCT04759534
What this trial is testing

Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Efficacy and SafetyHeterozygous Familial HypercholesterolemiaPCSK9
Shenzhen People's Hospital 20
Large-scale testing (Phase 3)Ended earlyNCT00151788
What this trial is testing

Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.

Who this might be right for
AtherosclerosisHeterozygous Familial Hypercholesterolemia
Daiichi Sankyo 796
Early research (Phase 1)Ended earlyNCT01583647
What this trial is testing

Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)

Who this might be right for
Hypercholesterolemia, FamilialHeterozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC 10
Early research (Phase 1)Study completedNCT00739999
What this trial is testing

8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Pediatric Heterozygous Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 39
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Large-scale testing (Phase 3)Study completedNCT00654602
What this trial is testing

48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety

Who this might be right for
Dyslipidaemia
AstraZeneca 1,500
Large-scale testing (Phase 3)Looking for participantsNCT06568471
What this trial is testing

A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia

Who this might be right for
HypercholesterolemiaDyslipidemiasPrimary Hypercholesterolemia+4 more
Hasten Biopharmaceutical Co., Ltd. 210
Large-scale testing (Phase 3)Looking for participantsNCT07465263
What this trial is testing

Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 135
Large-scale testing (Phase 3)Study completedNCT05142722
What this trial is testing

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+2 more
NewAmsterdam Pharma 2,530
Large-scale testing (Phase 3)Study completedNCT02326220
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 62
Large-scale testing (Phase 3)Study completedNCT01763918
What this trial is testing

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2

Who this might be right for
Hyperlipidemia
Amgen 331
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Study completedNCT00355615
What this trial is testing

PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin

Who this might be right for
Familial Hypercholesterolemia
AstraZeneca 173
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
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