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Results for “Heterozygous Familial Hypercholesterolemia (HeFH)”

40 trials

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Showing 20 of 40 results

Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Large-scale testing (Phase 3)Not Yet RecruitingNCT07465263
What this trial is testing

Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 135
Large-scale testing (Phase 3)Looking for participantsNCT07058077
What this trial is testing

Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 153
Large-scale testing (Phase 3)Study completedNCT01824238
What this trial is testing

The Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 68
Large-scale testing (Phase 3)Study completedNCT05142722
What this trial is testing

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+2 more
NewAmsterdam Pharma 2,530
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Testing effectiveness (Phase 2)Study completedNCT05694260
What this trial is testing

A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Who this might be right for
Hypercholesterolemia
Esperion Therapeutics, Inc. 31
Large-scale testing (Phase 3)Study completedNCT02326220
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 62
Large-scale testing (Phase 3)Active Not RecruitingNCT07000136
What this trial is testing

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH

Who this might be right for
Heterozygous Familial Hypercholesterolaemia
AstraZeneca 455
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Very early researchNot Yet RecruitingNCT07353398
What this trial is testing

Early-phase Study of ART002g1 Injection in HeFH: Safety, Tolerability and Preliminary Efficacy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 24
Testing effectiveness (Phase 2)Study completedNCT01266876
What this trial is testing

Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 77
Large-scale testing (Phase 3)Study completedNCT03067441
What this trial is testing

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Disease
Esperion Therapeutics, Inc. 1,462
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Not applicableLooking for participantsNCT06634160
What this trial is testing

Assessment of the Prevalence of Steatotic Liver Disease Associated With Metabolic Dysfunction in Patients With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Nantes University Hospital 200
Large-scale testing (Phase 3)Ended earlyNCT00384293
What this trial is testing

Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED)

Who this might be right for
Hypercholesterolemia, Familial
Merck Sharp & Dohme LLC 937
Large-scale testing (Phase 3)Ended earlyNCT01410383
What this trial is testing

Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of Care

Who this might be right for
Heterozygous Familial Hypercholesterolaemia
Karo Bio AB 236
Testing effectiveness (Phase 2)Study completedNCT03038022
What this trial is testing

Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Madrigal Pharmaceuticals, Inc. 116
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