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Results for “Heterozygous Familial Hypercholesterolemia (HeFH)”

41 trials

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Showing 20 of 41 results

Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Early research (Phase 1)Study completedNCT00739999
What this trial is testing

8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Pediatric Heterozygous Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 39
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Large-scale testing (Phase 3)Looking for participantsNCT07465263
What this trial is testing

Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 135
Large-scale testing (Phase 3)Study completedNCT05142722
What this trial is testing

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+2 more
NewAmsterdam Pharma 2,530
Large-scale testing (Phase 3)Study completedNCT02326220
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 62
Testing effectiveness (Phase 2)Study completedNCT01576484
What this trial is testing

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
HypercholesterolemiaHeterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 58
Large-scale testing (Phase 3)Study completedNCT01824238
What this trial is testing

The Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 68
Testing effectiveness (Phase 2)Study completedNCT01266876
What this trial is testing

Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 77
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 60
Not applicableLooking for participantsNCT06634160
What this trial is testing

Assessment of the Prevalence of Steatotic Liver Disease Associated With Metabolic Dysfunction in Patients With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Nantes University Hospital 200
Testing effectiveness (Phase 2)Study completedNCT04173793
What this trial is testing

PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Akeso 109
Not applicableLooking for participantsNCT07427472
What this trial is testing

"Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)"

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Assistance Publique - Hôpitaux de Paris 300
Not applicableLooking for participantsNCT07470723
What this trial is testing

The ORIGIN-FH Study

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)Homozygous Familial Hypercholesterolemia (HoFH)Familial Hypercholesterolemia
University of Wisconsin, Madison 70
Large-scale testing (Phase 3)Ended earlyNCT00384293
What this trial is testing

Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED)

Who this might be right for
Hypercholesterolemia, Familial
Merck Sharp & Dohme LLC 937
Large-scale testing (Phase 3)Looking for participantsNCT07058077
What this trial is testing

Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 153
Testing effectiveness (Phase 2)Study completedNCT03038022
What this trial is testing

Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Madrigal Pharmaceuticals, Inc. 116
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