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Results for “High Grade Serous Ovarian Cancer (HGSOC)”

28 trials

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Showing 20 of 28 results

Early research (Phase 1)Looking for participantsNCT06476808
What this trial is testing

Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Who this might be right for
High-grade Serous Ovarian Carcinoma (HGSOC)Uterine Serous Carcinoma (USC)Non-small Cell Lung Cancer (NSCLC)
Bristol-Myers Squibb 240
Early research (Phase 1)Looking for participantsNCT07503808
What this trial is testing

IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types

Who this might be right for
Esophageal Squamous Cell CarcinomaHigh Grade Serous Ovarian CancerHead and Neck Squamous Cell Carcinoma+5 more
IDEAYA Biosciences 150
Early research (Phase 1)Active Not RecruitingNCT04092270
What this trial is testing

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Who this might be right for
Endometrial High Grade Endometrioid AdenocarcinomaFallopian Tube Clear Cell AdenocarcinomaFallopian Tube Endometrioid Adenocarcinoma+26 more
National Cancer Institute (NCI) 54
Not applicableStudy completedNCT06787170
What this trial is testing

Prediction of Platinum Resistance and Prognosis of High-grade Serous Ovarian Cancer

Who this might be right for
High-grade Serous Ovarian Cancer (HGSOC)
The First People's Hospital of Yunnan 1,129
Early research (Phase 1)Study completedNCT02307240
What this trial is testing

Open Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Subjects With Advanced/Relapsed Solid Tumors

Who this might be right for
Triple-Negative Breast CancerHigh-grade Serous Ovarian CancerSolid Tumors+1 more
Curis, Inc. 43
Testing effectiveness (Phase 2)Ended earlyNCT05243524
What this trial is testing

Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer

Who this might be right for
Platinum-resistant Epithelial Ovarian Cancer
ImmunoVaccine Technologies, Inc. (IMV Inc.) 16
Testing effectiveness (Phase 2)Ended earlyNCT04718675
What this trial is testing

KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Who this might be right for
Relapsed Solid TumorsRefractory Solid TumorsNon-Hodgkin Lymphoma+2 more
Kronos Bio 135
Early research (Phase 1)Looking for participantsNCT06799065
What this trial is testing

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Who this might be right for
Advanced Solid TumorsBreast Cancer RecurrentOvarian Cancer+2 more
Accent Therapeutics 90
Early research (Phase 1)Ended earlyNCT05229900
What this trial is testing

SGN-ALPV in Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsCarcinoma, Non-Small-Cell Lung+4 more
Seagen Inc. 43
Not applicableNot Yet RecruitingNCT07461207
What this trial is testing

A Translational Study to Explore and Overcome Metabolic-driven Resistance Mechanisms to Standard Chemotherapy in High-grade Ovarian Cancer

Who this might be right for
High-grade Serous Ovarian Carcinoma (HGSOC)
IRCCS Azienda Ospedaliero-Universitaria di Bologna 120
Early research (Phase 1)Study completedNCT04293094
What this trial is testing

Study of AMG 650 in Adult Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Volastra Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Looking for participantsNCT05902988
What this trial is testing

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid TumorHigh Grade Serous Adenocarcinoma of OvarySquamous Non-small-cell Lung Cancer+7 more
Volastra Therapeutics, Inc. 200
Not applicableLooking for participantsNCT04846933
What this trial is testing

Multi-layer Data to Improve Diagnosis, Predict Therapy Resistance and Suggest Targeted Therapies in HGSOC

Who this might be right for
High Grade Ovarian Serous AdenocarcinomaHigh Grade Serous Carcinoma
Turku University Hospital 200
Early research (Phase 1)Ended earlyNCT04893551
What this trial is testing

Tilvestamab (BGB149) in Relapsed, Platinum-resistant, High-grade Serous Ovarian Cancer (HGSOC) Participants

Who this might be right for
Ovarian Neoplasms
BerGenBio ASA 16
Not applicableEnded earlyNCT03922776
What this trial is testing

Phenotypic Characterization Tumor-infiltrating Lymphocytes at Diagnosis and After Chemotherapy in Ovarian Cancer

Who this might be right for
Ovarian Cancer Stage IIICFallopian Tube Cancer Stage IIICFallopian Tube Cancer Stage IV+1 more
Centre Oscar Lambret 36
Early research (Phase 1)Looking for participantsNCT05005403
What this trial is testing

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Who this might be right for
Non-Small Cell Lung CancerHead and Neck Squamous Cell CarcinomaMicro Satellite Stable Colorectal Cancer+4 more
AbbVie
Testing effectiveness (Phase 2)Looking for participantsNCT06188520
What this trial is testing

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors

Who this might be right for
ER+ HER2- Advanced Breast CancerHigh-grade Serous Ovarian Cancer (HGSOC)
AstraZeneca 564
Not applicableLooking for participantsNCT06466382
What this trial is testing

OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy

Who this might be right for
Ovarian Neoplasm EpithelialFallopian Tube NeoplasmsOvarian Endometrioid Carcinoma+1 more
Swiss GO Trial Group 60
Testing effectiveness (Phase 2)WithdrawnNCT05714306
What this trial is testing

PEP-DC and OC-DC Vaccine in High Grade Serous Ovarian Carcinoma

Who this might be right for
Ovarian Carcinoma
Centre Hospitalier Universitaire Vaudois
Early research (Phase 1)Looking for participantsNCT04389632
What this trial is testing

Sigvotatug Vedotin in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer 1,006
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