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Results for “High LDL-c”

132 trials

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Showing 20 of 132 results

Not applicableStudy completedNCT00347217
What this trial is testing

Observational to Investigate the Efficacy of CRESTOR 5mg in Reaching LDL-C Target Goals in Patients Who Are at High Risk for a Cardiovascular Event

Who this might be right for
Hypercholesteremia
AstraZeneca 3,840
Post-approval studies (Phase 4)Study completedNCT00644709
What this trial is testing

Atorvastatin For The Treatment Of High Cholesterol In Patients At High Risk Of Coronary Heart Disease (CHD)

Who this might be right for
Dyslipidemias
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 196
Large-scale testing (Phase 3)Study completedNCT04929249
What this trial is testing

Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE)

Who this might be right for
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals 450
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Testing effectiveness (Phase 2)Study completedNCT01105975
What this trial is testing

LY2484595 in Patients With High LDL-C or Low HDL-C

Who this might be right for
Dyslipidemia
Eli Lilly and Company 398
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 51
Large-scale testing (Phase 3)Study completedNCT04807400
What this trial is testing

Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support

Who this might be right for
Atherosclerotic Cardiovascular DiseaseAtherosclerotic Cardiovascular Disease Risk EquivelentsElevated Low Density Lipoprotein Cholesterol
Novartis Pharmaceuticals 892
Not applicableNot Yet RecruitingNCT05587621
What this trial is testing

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)

Who this might be right for
ST Elevation Myocardial InfarctionNon-ST Elevation Myocardial InfarctionLDL-cholesterol
Jena University Hospital 300
Not applicableNot Yet RecruitingNCT06821711
What this trial is testing

Optimal LDL-C Target in High-risk Patients After PCI

Who this might be right for
Chronic Coronary SyndromeAcute Coronary SyndromesPercutaneous Coronary Intervention+1 more
Xijing Hospital 12,000
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Post-approval studies (Phase 4)Study completedNCT01896037
What this trial is testing

Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels

Who this might be right for
Spinal Cord InjuryTetraplegiaQuadraplegia+2 more
University of Manitoba 21
Post-approval studies (Phase 4)Active Not RecruitingNCT04951856
What this trial is testing

Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI

Who this might be right for
STEMI - ST Elevation Myocardial InfarctionNSTEMI - Non-ST Segment Elevation MI
Assistance Publique - Hôpitaux de Paris 2,166
Not applicableStudy completedNCT01690312
What this trial is testing

Clinical Study to Assess High-DHA Fish Oil on Biomarkers of Cardiovascular Disease Risk in Adults on Statin Therapy

Who this might be right for
Cardiovascular Disease
Nutrasource Pharmaceutical and Nutraceutical Services, Inc. 36
Early research (Phase 1)Study completedNCT02314442
What this trial is testing

An Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Hypercholesterolemia
Alnylam Pharmaceuticals 70
Post-approval studies (Phase 4)Study completedNCT03993236
What this trial is testing

Study on Rosuvastatin+Ezetimibe and Rosuvastatin for LDL-C Goal in Patients With Recent Ischemic Stroke

Who this might be right for
Stroke, Ischemic
Keun-Sik Hong 584
Not applicableEnded earlyNCT01580319
What this trial is testing

Primary Prevention of Cardiovascular Diseases in Childhood and Adolescence: the Role of Physical Activity

Who this might be right for
ObesityHypercholesterolemiaHigh Blood Pressure+1 more
Instituto de Cardiologia do Rio Grande do Sul 27
Early research (Phase 1)Looking for participantsNCT07423598
What this trial is testing

Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels

Who this might be right for
Healthy Participants
AstraZeneca 40
Early research (Phase 1)Study completedNCT03427710
What this trial is testing

A First In Human Study to Assess CiVi007 in Subjects With an Elevated LDL-Cholesterol Level

Who this might be right for
Hypercholesterolemia
Civi Biopharma, Inc. 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07477704
What this trial is testing

See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 420
Large-scale testing (Phase 3)Study completedNCT02392559
What this trial is testing

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Amgen 158
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