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Results for “High LDL-c”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT01426412
What this trial is testing

LY3015014 in Healthy Participants With Elevated Low Density Lipoprotein Cholesterol

Who this might be right for
Hyperlipidemia
Eli Lilly and Company 69
Not applicableNot Yet RecruitingNCT05587621
What this trial is testing

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)

Who this might be right for
ST Elevation Myocardial InfarctionNon-ST Elevation Myocardial InfarctionLDL-cholesterol
Jena University Hospital 300
Large-scale testing (Phase 3)Not Yet RecruitingNCT07242599
What this trial is testing

Ongericimab Injection Reducing Recurrence of Ischemic Stroke

Who this might be right for
Ischemic Cerebral Infarction
Beijing Tiantan Hospital 4,810
Early research (Phase 1)Study completedNCT07423598
What this trial is testing

Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels

Who this might be right for
Healthy Participants
AstraZeneca 40
Early research (Phase 1)Study completedNCT06132360
What this trial is testing

The Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects in Adult Subjects With Elevated LDL-C

Who this might be right for
To Reduce the LDL-C Level in Hypercholesteremia Patients
Shanghai Rona Therapeutics Co., Ltd. 32
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Testing effectiveness (Phase 2)Study completedNCT02597127
What this trial is testing

Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)

Who this might be right for
Atherosclerotic Cardiovascular DiseaseFamilial HypercholesterolemiaDiabetes
The Medicines Company 501
Not applicableStudy completedNCT00574782
What this trial is testing

Evaluation of the Efficacy of Rosuvastatin in Daily Practice in Untreated High Risk Patients (CHALLENGE)

Who this might be right for
HypercholesterolemiaCoronary Heart DiseasePeripheral Vascular Disease+2 more
AstraZeneca 2,660
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Large-scale testing (Phase 3)Study completedNCT02585778
What this trial is testing

Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)

Who this might be right for
Hypercholesterolaemia
Sanofi 517
Post-approval studies (Phase 4)Looking for participantsNCT06501443
What this trial is testing

LATAM LOWERS LDL-C

Who this might be right for
Hypercholesterolaemia
Novartis Pharmaceuticals 520
Large-scale testing (Phase 3)Study completedNCT01879319
What this trial is testing

Study to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a Prefilled Autoinjector/Pen

Who this might be right for
Primary HypercholesterolemiaMixed Dyslipidemia
Amgen 164
Large-scale testing (Phase 3)Study completedNCT05004675
What this trial is testing

Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients

Who this might be right for
HypercholesterolemiaAtherosclerotic Ischemic Disease
LIB Therapeutics LLC 166
Large-scale testing (Phase 3)Enrolling By InvitationNCT04798430
What this trial is testing

Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction

Who this might be right for
Cardiovascular Disease With Mention of ArteriosclerosisElevated CholesterolFamilial Hypercholesterolemia
LIB Therapeutics LLC 2,000
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Not applicableStudy completedNCT01245738
What this trial is testing

Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204)

Who this might be right for
DyslipidemiasHypercholesterolemiaHypertriglyceridemia+2 more
Merck Sharp & Dohme LLC 635
Not applicableStudy completedNCT00240344
What this trial is testing

Study in High Risk Patients Switched From Higher Doses of Other Statins to Crestor on the Percentage of Patients Reaching the New LDL-C Target Goal

Who this might be right for
Hypercholesterolemia
AstraZeneca 2,650
Post-approval studies (Phase 4)Study completedNCT00644709
What this trial is testing

Atorvastatin For The Treatment Of High Cholesterol In Patients At High Risk Of Coronary Heart Disease (CHD)

Who this might be right for
Dyslipidemias
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 196
Testing effectiveness (Phase 2)Study completedNCT03051100
What this trial is testing

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C

Who this might be right for
Hypercholesterolemia
Esperion Therapeutics, Inc. 63
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
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