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Results for “High Risk MDS or AML Patients”

192 trials

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Showing 20 of 192 results

Early research (Phase 1)Study completedNCT01300572
What this trial is testing

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Who this might be right for
Chronic Myelomonocytic LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center 16
Testing effectiveness (Phase 2)Study completedNCT00096122
What this trial is testing

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+20 more
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)Study completedNCT03128359
What this trial is testing

High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant

Who this might be right for
Acute LeukemiaChronic Lymphocytic Leukemia/Small Lymphocytic LymphomaChronic Myelogenous Leukemia, BCR-ABL1 Positive+12 more
City of Hope Medical Center 38
Early research (Phase 1)WithdrawnNCT05823480
What this trial is testing

Magrolimab in Combination with Azacitidine After Allogeneic HCTin Treating Patients with High-Risk AML or MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
City of Hope Medical Center
Early research (Phase 1)Ended earlyNCT00589316
What this trial is testing

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+7 more
Fred Hutchinson Cancer Center
Large-scale testing (Phase 3)Study completedNCT03092674
What this trial is testing

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia
National Cancer Institute (NCI) 76
Testing effectiveness (Phase 2)Ended earlyNCT04849910
What this trial is testing

Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Vor Biopharma 67
Early research (Phase 1)Looking for participantsNCT04243785
What this trial is testing

BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
Edgewood Oncology Inc. 80
Very early researchStudy completedNCT02233504
What this trial is testing

Pilot Study to Assess Hematologic Response in Patients With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndromes Undergoing Monotherapy With Exjade (Deferasirox)

Who this might be right for
High Risk MDS or AML Patients
Abramson Cancer Center at Penn Medicine 25
Testing effectiveness (Phase 2)Study completedNCT03672539
What this trial is testing

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaHigh Risk Myelodysplastic Syndrome+3 more
M.D. Anderson Cancer Center 50
Testing effectiveness (Phase 2)Study completedNCT00077116
What this trial is testing

Idarubicin, Cytarabine, and Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia Secondary to Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic Syndromes
European Organisation for Research and Treatment of Cancer - EORTC 31
Testing effectiveness (Phase 2)Ended earlyNCT00185679
What this trial is testing

Haploid Allogeneic Transplant Using the CliniMACS System

Who this might be right for
Acute Myelogenous Leukemia (AML) - Relapsed, Primary Refractory Disease or Poor Risk FactorsChronic Myelogenous Leukemia (CML) - Accelerated or Second Chronic PhaseMyelodysplastic Syndrome (MDS) - High and Intermediate Risk+2 more
Ginna Laport 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07562568
What this trial is testing

SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMDS+4 more
The First Affiliated Hospital of Soochow University 160
Early research (Phase 1)Study completedNCT05829226
What this trial is testing

Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

Who this might be right for
AML, Adult RecurrentMDS
PureTech 101
Early research (Phase 1)Study completedNCT01757639
What this trial is testing

Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaMyelodysplastic Syndrome+3 more
National Cancer Institute (NCI) 42
Early research (Phase 1)Looking for participantsNCT06146257
What this trial is testing

GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
GluBio Therapeutics Inc. 48
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Testing effectiveness (Phase 2)Looking for participantsNCT06717958
What this trial is testing

Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation

Who this might be right for
AMLMDS
Technische Universität Dresden 76
Testing effectiveness (Phase 2)Ended earlyNCT02198482
What this trial is testing

Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)High-risk Myelodysplastic Syndrome (MDS)
University of Ulm 6
Early research (Phase 1)Ended earlyNCT00049582
What this trial is testing

Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+10 more
National Cancer Institute (NCI) 36
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