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Results for “High Risk Myelodysplasia”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT01272245
What this trial is testing

Omacetaxine and Low Dose Cytarabine in Older Patients With Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 36
Very early researchUnknownNCT04156256
What this trial is testing

CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAcute Myeloid LeukemiaMyelodysplastic Syndromes+2 more
iCell Gene Therapeutics 20
Testing effectiveness (Phase 2)UnknownNCT00328237
What this trial is testing

Treatment of Hematologic Malignancies With Single-Unit or Double-Unit Cord Blood Transplantation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myeloid Leukemia+2 more
Colorado Blood Cancer Institute 20
Not applicableEnded earlyNCT02179359
What this trial is testing

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more
Masonic Cancer Center, University of Minnesota 38
Testing effectiveness (Phase 2)Study completedNCT01729845
What this trial is testing

Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
Previously Treated Myelodysplastic SyndromeRecurrent Adult Acute Myeloid Leukemia
Fred Hutchinson Cancer Center 52
Large-scale testing (Phase 3)Study completedNCT03268954
What this trial is testing

Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML)

Who this might be right for
Myelodysplastic SyndromeLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute
Takeda 454
Testing effectiveness (Phase 2)Study completedNCT03824080
What this trial is testing

Evaluating the Efficacy and Safety of Bemcentinib in Patients With Myelodysplastic Syndromes

Who this might be right for
Acute Myeloid LeukemiaHigh-risk Myelodysplastic SyndromeLow-risk Myelodysplastic Syndrome
GWT-TUD GmbH 45
Testing effectiveness (Phase 2)Looking for participantsNCT06196203
What this trial is testing

AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

Who this might be right for
Higher-risk Myelodysplastic Syndromes
Akeso 90
Testing effectiveness (Phase 2)Study completedNCT03433781
What this trial is testing

A Phase Ib Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations

Who this might be right for
Myelodysplastic Syndromes
NYU Langone Health 4
Testing effectiveness (Phase 2)Study completedNCT03047993
What this trial is testing

Glutaminase Inhibitor CB-839 and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Multilineage DysplasiaBlasts 20-30 Percent of Bone Marrow Nucleated CellsBlasts 20-30 Percent of Peripheral Blood White Cells+4 more
M.D. Anderson Cancer Center 28
Testing effectiveness (Phase 2)Looking for participantsNCT03128034
What this trial is testing

211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia+9 more
Fred Hutchinson Cancer Center 75
Early research (Phase 1)Active Not RecruitingNCT02530034
What this trial is testing

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveHematopoietic and Lymphoid Cell Neoplasm+8 more
M.D. Anderson Cancer Center 72
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Testing effectiveness (Phase 2)Looking for participantsNCT05817955
What this trial is testing

Clinical Study of Azacitidine Combined With Ruxolitinib in the Treatment of Higher-risk MDS/MPN

Who this might be right for
MDS/MPN
The First Affiliated Hospital with Nanjing Medical University 50
Testing effectiveness (Phase 2)WithdrawnNCT05829434
What this trial is testing

Magrolimab Plus Intensive Chemotherapy in Newly Diagnosed AML or HR-MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Neoplasm
Uwe Platzbecker
Early research (Phase 1)UnknownNCT00769613
What this trial is testing

Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections

Who this might be right for
Cancer
Milton S. Hershey Medical Center 20
Testing effectiveness (Phase 2)Ended earlyNCT02159040
What this trial is testing

Phase II Study to Evaluate Overall Response in Patients With Higher Risk Myelodysplastic Syndromes (MDS) Treated With Azacitidine With or Without Deferasirox.

Who this might be right for
High Risk MDS
Novartis Pharmaceuticals 1
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06900088
What this trial is testing

Selinexor Combined With Azacitidine Therapy in High-Risk Myeloid Neoplasms Patients

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeChronic Myelomonocytic Leukemia
Institute of Hematology & Blood Diseases Hospital, China 20
Not applicableLooking for participantsNCT01210274
What this trial is testing

Characterization of the Mechanisms of Resistance to Azacitidine

Who this might be right for
Myelodysplastic Syndromes or Acute Myeloid Leukemia With Multilineage Dysplasia
Centre Hospitalier Universitaire de Nice 250
Testing effectiveness (Phase 2)Looking for participantsNCT06928662
What this trial is testing

Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse

Who this might be right for
Acute Myeloid LeukemiaAcute Undifferentiated LeukemiaMixed Phenotype Acute Leukemia+11 more
Fred Hutchinson Cancer Center 36
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