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Results for “High Risk Non-Muscle Invasive Bladder Urothelial Carcinoma”

46 trials

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Showing 20 of 46 results

Not applicableNot Yet RecruitingNCT06324058
What this trial is testing

Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC

Who this might be right for
Bladder Cancer
Huashan Hospital 190
Large-scale testing (Phase 3)Looking for participantsNCT06696794
What this trial is testing

Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC Patients

Who this might be right for
Non-Muscle-Invasive Bladder Cancer (NMIBC)
Shaogang Wang 180
Not applicableLooking for participantsNCT05123625
What this trial is testing

Prognostic Effect of Whether Doing PLND During RC for High-risk NMIBC

Who this might be right for
Bladder Cancer
The First Affiliated Hospital with Nanjing Medical University 200
Testing effectiveness (Phase 2)Looking for participantsNCT06770582
What this trial is testing

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Who this might be right for
Non-Muscle Invasive Bladder Urothelial CarcinomaRecurrent Non-Muscle Invasive Bladder Urothelial CarcinomaStage I Bladder Cancer AJCC v8
National Cancer Institute (NCI) 160
Large-scale testing (Phase 3)Study completedNCT00406068
What this trial is testing

Mycobacterial Cell Wall-DNA Complex in Treatment of BCG-refractory Patients With Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder Neoplasms
Bioniche Life Sciences Inc. 129
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07356791
What this trial is testing

Phase II Prospective Cohort Study of Intravesical Recombinant Human Type 5 Adenovirus Injection for Treatment of High-Risk Non-Muscle Invasive Bladder Cancer: Evaluating Efficacy and Safety

Who this might be right for
Bladder (Urothelial, Transitional Cell) Cancer
RenJi Hospital 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT03504163
What this trial is testing

Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

Who this might be right for
Bladder Cancer
Memorial Sloan Kettering Cancer Center 45
Post-approval studies (Phase 4)Active Not RecruitingNCT04701151
What this trial is testing

NORTH-REG Dwell-Time Study

Who this might be right for
Side Effect of Drug
Jørgen Bjerggaard Jensen 314
Testing effectiveness (Phase 2)Study completedNCT01939756
What this trial is testing

Intravesical Natural Baobab Oil in the Management of BCG-induced Lower Urinary Tract Symptoms

Who this might be right for
Superficial Bladder CancerLower Urinary Tract Symptoms
Savino M. Di Stasi 50
Testing effectiveness (Phase 2)Study completedNCT03636256
What this trial is testing

Evaluation of NanoDoce® in Participants With Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaUrinary Bladder Neoplasm+6 more
NanOlogy, LLC 36
Not applicableNot Yet RecruitingNCT06982690
What this trial is testing

Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial

Who this might be right for
NMIBCTURBTBladder (Urothelial, Transitional Cell) Cancer+3 more
National Taiwan University Hospital 370
Post-approval studies (Phase 4)Looking for participantsNCT05962541
What this trial is testing

Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs)

Who this might be right for
Non-muscle-invasive Bladder CancerNon-Muscle Invasive Bladder Urothelial CarcinomaHigh Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
University of Roma La Sapienza 327
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07100184
What this trial is testing

RC48 in Combination With Radiotherapy for HER2-Expressing NMIBC Patients

Who this might be right for
HER2-expressing High-risk or Very High-risk NMIBC Without Visible Foci of Disease After TURBT
Peking University First Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07189793
What this trial is testing

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

Who this might be right for
Urinary Bladder NeoplasmsCarcinoma, Transitional CellCarcinoma in Situ of Bladder+1 more
First Affiliated Hospital of Wenzhou Medical University 106
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Testing effectiveness (Phase 2)UnknownNCT05418309
What this trial is testing

Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable: a Multi-center Study

Who this might be right for
High-Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
Tianjin Medical University Second Hospital 63
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06972615
What this trial is testing

Intravesical Chemotherapy in Combination With Systemic Pembrolizumab in NMIBC Unresponsive to BCG Therapy

Who this might be right for
Non Muscle Invasive Bladder Cancer
BLATAM 37
Testing effectiveness (Phase 2)Looking for participantsNCT03317158
What this trial is testing

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Who this might be right for
Urothelial CarcinomaBladder Cancer
Noah Hahn, M.D. 55
Early research (Phase 1)Looking for participantsNCT05843448
What this trial is testing

IDO and PD-L1 Peptide Based Immune-Modulatory Therapeutic (IO102-IO103) in Combination With Pembrolizumab for BCG-Unresponsive or Intolerant, Non-Muscle Invasive Bladder Cancer

Who this might be right for
High Risk Non-Muscle Invasive Bladder Urothelial CarcinomaStage 0a Bladder Cancer AJCC v8Stage 0is Bladder Cancer AJCC v8+1 more
University of California, Davis 30
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