Early research (Phase 1)Study completedNCT03154996What this trial is testingChronic Convection Enhanced Delivery of TopotecanWho this might be right forGliomas Jeffrey N. Bruce 5
Not applicableStudy completedNCT03775369What this trial is testingGlioma and ExercisingWho this might be right forHigh Grade Glioma University Hospital, Basel, Switzerland 39
Early research (Phase 1)Ended earlyNCT02168270What this trial is testingTemozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade GliomaWho this might be right forAnaplastic AstrocytomaAnaplastic OligodendrogliomaAnaplastic Oligoastrocytoma+2 more University of Nebraska 4
Early research (Phase 1)Looking for participantsNCT06815029What this trial is testingIntracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant AstrocytomaWho this might be right forRecurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma City of Hope Medical Center 27
Testing effectiveness (Phase 2)Ended earlyNCT03352427What this trial is testingStudy of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) AlterationsWho this might be right forGliomaHigh Grade GliomaPontine Tumors University of Michigan Rogel Cancer Center 3
Early research (Phase 1)Not Yet RecruitingNCT07492316What this trial is testingRNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB)Who this might be right forRecurrent Medulloblastoma University of Florida 24
Testing effectiveness (Phase 2)Study completedNCT01390948What this trial is testingBevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade GliomaWho this might be right forHigh Grade Glioma Hoffmann-La Roche 124
Early research (Phase 1)Study completedNCT00075894What this trial is testingAlanosine in Treating Patients With Progressive or Recurrent Malignant GliomasWho this might be right forBrain and Central Nervous System Tumors National Cancer Institute (NCI) 18
Not applicableStudy completedNCT00006342What this trial is testingGenetic Study in Patients Receiving Treatment for Hodgkin's Disease or Childhood Brain TumorWho this might be right forBrain and Central Nervous System TumorsLymphoma Duke University 19
Testing effectiveness (Phase 2)Ended earlyNCT01095094What this trial is testingRitonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade GliomaWho this might be right forBrain TumorAnaplastic AstrocytomaAnaplastic Ependymoma+6 more Case Comprehensive Cancer Center 19
Not applicableLooking for participantsNCT06975332What this trial is testingLocal, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) ProgressionWho this might be right forGlioblastomaHigh-Grade GliomasGrade III Astrocytoma+1 more Medical University of Warsaw 35
Not applicableLooking for participantsNCT06740097What this trial is testingFeasibility of Aspirate Tissue Monitoring in Neuro-oncological SurgeryWho this might be right forHigh Grade Gliomas Kuopio University Hospital 50
Not applicableStudy completedNCT05375318What this trial is testingBIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological LevelsWho this might be right forAstrocytoma, Grade IVGlioblastomaGlioblastoma Multiforme+5 more Juan M Garcia-Gomez 50
Very early researchNot Yet RecruitingNCT07210632What this trial is testingWindow Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)Who this might be right forBrain CancerHGGGlioma+4 more Eben Rosenthal 38
Testing effectiveness (Phase 2)Looking for participantsNCT06528691What this trial is testingEntrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS TumorsWho this might be right forHigh Grade GliomaCNS Tumor St. Jude Children's Research Hospital 52
Not applicableStudy completedNCT04726397What this trial is testingUNIty-Based MR-Linac Guided AdapTive RadiothErapy for High GraDe Glioma: a Phase 2 TrialWho this might be right forGlioblastoma Multiforme Sunnybrook Health Sciences Centre 108
Very early researchStudy completedNCT04937413What this trial is testingThe PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics EvaluationWho this might be right forMalignant GliomaGlioblastoma Duke University 32
Early research (Phase 1)Active Not RecruitingNCT02192359What this trial is testingCarboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade GliomasWho this might be right forRecurrent Anaplastic AstrocytomaRecurrent Anaplastic OligoastrocytomaRecurrent Anaplastic Oligodendroglioma+4 more City of Hope Medical Center 18
Very early researchStudy completedNCT01678352What this trial is testingImiquimod and Tumor Lysate Vaccine Immunotherapy in Adults With High Risk or Recurrent Grade II GliomasWho this might be right forHigh Risk WHO Grade II GliomaRecurrent/Post-Chemotherapy WHO Grade II Glioma Frank Lieberman 19
Testing effectiveness (Phase 2)Ended earlyNCT00003535What this trial is testingAntineoplaston Therapy in Treating Children With Recurrent or Refractory High-Grade GliomaWho this might be right forHigh Grade Glioma Burzynski Research Institute 9