Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “High-Risk Myelodysplastic Syndromes”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT00776503
What this trial is testing

Vorinostat and Low Dose Cytarabine for High Risk Myelodysplasia

Who this might be right for
Myelodysplastic Syndromes
Groupe Francophone des Myelodysplasies 52
Early research (Phase 1)Ended earlyNCT05209152
What this trial is testing

AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia

Who this might be right for
Higher Risk Myelodysplastic SyndromeChronic Myelomonocytic Leukemia
Amgen 7
Early research (Phase 1)Study completedNCT01629082
What this trial is testing

Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

Who this might be right for
Myeldysplastic Syndrome (MDS)Chronic Myelomonocytic LeukemiaBone Marrow Diseases+2 more
National Heart, Lung, and Blood Institute (NHLBI) 4
Testing effectiveness (Phase 2)WithdrawnNCT01324960
What this trial is testing

Azacitidine With or Without Ceplene/Interleukin-2 in Patients With Higher Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Groupe Francophone des Myelodysplasies
Early research (Phase 1)Study completedNCT00875745
What this trial is testing

Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Promyelocytic, AcuteMyelodysplastic Syndromes
Indiana University 15
Testing effectiveness (Phase 2)Ended earlyNCT02152956
What this trial is testing

Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)

Who this might be right for
AML
MacroGenics 244
Testing effectiveness (Phase 2)Study completedNCT01101880
What this trial is testing

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+8 more
University of Washington 50
Very early researchUnknownNCT03795779
What this trial is testing

CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies

Who this might be right for
Hematologic MalignancyAcute Myeloid LeukemiaMyelodysplastic Syndromes+2 more
iCell Gene Therapeutics 20
Testing effectiveness (Phase 2)WithdrawnNCT04109690
What this trial is testing

CPX-351 in Patients Treated for Higher-risk Myelodysplastic Syndromes Experiencing Hypomethylating Agent Failure.

Who this might be right for
MDS
Yale University
Early research (Phase 1)Looking for participantsNCT03630991
What this trial is testing

Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive+15 more
M.D. Anderson Cancer Center 58
Testing effectiveness (Phase 2)Study completedNCT01238211
What this trial is testing

Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11+5 more
National Cancer Institute (NCI) 61
Testing effectiveness (Phase 2)Study completedNCT05115630
What this trial is testing

Off-the-shelf NK Cells + SCT for Myeloid Malignancies

Who this might be right for
Myeloid MalignanciesAcute Myeloid LeukemiaMyelodysplastic Syndrome+1 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Ended earlyNCT00143884
What this trial is testing

Study of Low Intensity Conditioning and Immunotherapy for High-Risk Cancers of the Blood

Who this might be right for
LeukemiaLymphoma, Low-GradeLymphoma, Non-Hodgkin's+2 more
University of Michigan Rogel Cancer Center 30
Large-scale testing (Phase 3)Study completedNCT00005863
What this trial is testing

Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasms
Medical Research Council
Testing effectiveness (Phase 2)WithdrawnNCT04985656
What this trial is testing

Pevonedistat Combined With Decitabine and Cedazuridine in Adults With Higher-risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes (MDS)
Takeda
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Testing effectiveness (Phase 2)Ended earlyNCT00698685
What this trial is testing

Pentostatin and Alemtuzumab as a Preparative Regimen for Allogeneic Peripheral Blood Stem Cell Transplantation

Who this might be right for
LeukemiaLymphomaHodgkin's Disease+3 more
University of Arizona 14
Not applicableNo Longer AvailableNCT04484363
What this trial is testing

Expanded Access Program With Pevonedistat (Given With Azacitidine) for Adults With Higher-risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Takeda
Testing effectiveness (Phase 2)Study completedNCT03030612
What this trial is testing

ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
OncoVerity, Inc. 38
Testing effectiveness (Phase 2)Looking for participantsNCT07238712
What this trial is testing

Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched Donor

Who this might be right for
Acute Myeloid Leukemia (AML)Chronic Myeloid LeukemiaMyelodysplastic Syndromes (MDS)+2 more
St. Petersburg State Pavlov Medical University 60
Next Page