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Results for “High-Risk NMIBC”

95 trials

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Showing 20 of 95 results

Large-scale testing (Phase 3)Active Not RecruitingNCT03528694
What this trial is testing

Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer

Who this might be right for
Non-muscle-invasive Bladder Cancer
AstraZeneca 1,018
Post-approval studies (Phase 4)Active Not RecruitingNCT04701151
What this trial is testing

NORTH-REG Dwell-Time Study

Who this might be right for
Side Effect of Drug
Jørgen Bjerggaard Jensen 314
Early research (Phase 1)UnknownNCT04134000
What this trial is testing

Atezolizumab and BCG in High Risk BCG naïve Non-muscle Invasive Bladder Cancer (NMIBC) Patients (BladderGATE)

Who this might be right for
Invasive Bladder Cancer
Fundacion Oncosur 40
Testing effectiveness (Phase 2)Looking for participantsNCT07322263
What this trial is testing

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

Who this might be right for
Bladder CancerNon-Muscle Invasive Bladder Cancer (NMIBC)Urothelial Carcinoma+8 more
Michael A. O'Donnell 174
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Testing effectiveness (Phase 2)Looking for participantsNCT07307456
What this trial is testing

Toripalimab Combined With BCG Perfusion for the Treatment of HR-NMIBC After TURBT Surgery Exploration

Who this might be right for
Bladder Cancer
Changhai Hospital 31
Not applicableUnknownNCT06324058
What this trial is testing

Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC

Who this might be right for
Bladder Cancer
Huashan Hospital 190
Post-approval studies (Phase 4)Study completedNCT02214602
What this trial is testing

Value of Immediate Post-operative Intravesical Epirubicin in Intermediate&High Risk Non Muscle Invasive Bladder Cancer

Who this might be right for
Carcinoma of Urinary Bladder, Superficial
Mansoura University 240
Testing effectiveness (Phase 2)Looking for participantsNCT05951179
What this trial is testing

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

Who this might be right for
Non-muscle Invasive Bladder Cancer
Protara Therapeutics 131
Not applicableLooking for participantsNCT07036731
What this trial is testing

A Study Comparing the Necessity of a Second Transurethral Resection in High-Risk Non-Muscle-Invasive Bladder Cancer Patients With Negative Results From Post-Initial Resection Urine Genome-Wide Low-Depth Sequencing

Who this might be right for
Non Muscle Invasive Bladder Cancer
The First Affiliated Hospital with Nanjing Medical University 428
Large-scale testing (Phase 3)Active Not RecruitingNCT05714202
What this trial is testing

TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)

Who this might be right for
Bladder Cancer
Janssen Research & Development, LLC 1,135
Not applicableEnded earlyNCT04412070
What this trial is testing

Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

Who this might be right for
Bladder Cancer
Hopital Foch 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07777848
What this trial is testing

Evaluate the Efficacy and Safety of RAG-01 as Monotherapy and in Combination With Chemotherapy in Patients With Non-muscle Invasive Bladder Cancer (NMIBC).

Who this might be right for
Non-muscle Invasive Bladder Cancer (NMIBC)
Ractigen Therapeutics. 114
Early research (Phase 1)Study completedNCT05085990
What this trial is testing

Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1b)

Who this might be right for
Non-muscle Invasive Bladder Cancer
Protara Therapeutics 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07189793
What this trial is testing

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

Who this might be right for
Urinary Bladder NeoplasmsCarcinoma, Transitional CellCarcinoma in Situ of Bladder+1 more
First Affiliated Hospital of Wenzhou Medical University 106
Testing effectiveness (Phase 2)Active Not RecruitingNCT04706598
What this trial is testing

Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

Who this might be right for
Urinary Bladder NeoplasmsImmunotherapy
Fudan University 25
Large-scale testing (Phase 3)UnknownNCT04490993
What this trial is testing

Safety and Efficacy of APL-1202 in Combination With Epirubicin Hydrochloride Versus Epirubicin Hydrochloride Alone in Intermediate and High-risk Chemo-refractory Non-muscle Invasive Bladder Cancer (NMIBC) Patients

Who this might be right for
Non-muscle Invasive Bladder Cancer
Jiangsu Yahong Meditech Co., Ltd aka Asieris 359
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Early research (Phase 1)Study completedNCT03191578
What this trial is testing

Immunological Response to Intravesical BCG Therapy of Superficial Bladder Cancer by Prior Administration of RUTI®

Who this might be right for
High-Risk Non-Muscle-Invasive Bladder Cancer
Archivel Farma S.L. 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06588179
What this trial is testing

SHR-1501 Combined With SHR-2005 for High-Risk Non-Muscle Invasive Bladder Cancer Which is Not Completely Resectable by TURBt

Who this might be right for
NMIBC
Fudan University 58
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