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Results for “High-Risk Non-Muscle Invasive Bladder Urothelial Carcinoma”

46 trials

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Showing 20 of 46 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05943106
What this trial is testing

BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants

Who this might be right for
Non-Muscle- Invasive Bladder Cancer
AstraZeneca 100
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07189793
What this trial is testing

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

Who this might be right for
Urinary Bladder NeoplasmsCarcinoma, Transitional CellCarcinoma in Situ of Bladder+1 more
First Affiliated Hospital of Wenzhou Medical University 106
Not applicableLooking for participantsNCT06991868
What this trial is testing

Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)

Who this might be right for
NMIBCMIBCUTUC
Peking University First Hospital 300
Not applicableUnknownNCT05276167
What this trial is testing

Hyperthermic Intravesical Perfusion for Muscle-invasive Bladder Urothelial Carcinoma

Who this might be right for
High-Risk, Non-Muscle Invasive Bladder Urothelial CarcinomaPerfusion; ComplicationsIntraoperative Complications
Henan Cancer Hospital 40
Testing effectiveness (Phase 2)Study completedNCT04311580
What this trial is testing

Intravesical Electromotive Mitomycin After Bacillus Calmette-Guérin Failure

Who this might be right for
Bladder Cancer
University of Rome Tor Vergata 52
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06972615
What this trial is testing

Intravesical Chemotherapy in Combination With Systemic Pembrolizumab in NMIBC Unresponsive or Exposed to BCG Therapy

Who this might be right for
Non Muscle Invasive Bladder Cancer
BLATAM 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT04706598
What this trial is testing

Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

Who this might be right for
Urinary Bladder NeoplasmsImmunotherapy
Fudan University 25
Large-scale testing (Phase 3)Looking for participantsNCT06696794
What this trial is testing

Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC Patients

Who this might be right for
Non-Muscle-Invasive Bladder Cancer (NMIBC)
Shaogang Wang 180
Large-scale testing (Phase 3)Looking for participantsNCT05037279
What this trial is testing

Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients with Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC)

Who this might be right for
Bladder CancerBladder Cancer RecurrentNeoplasm Recurrence+3 more
Verity Pharmaceuticals Inc. 540
Not applicableEnded earlyNCT04412070
What this trial is testing

Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

Who this might be right for
Bladder Cancer
Hopital Foch 20
Testing effectiveness (Phase 2)Looking for participantsNCT03317158
What this trial is testing

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Who this might be right for
Urothelial CarcinomaBladder Cancer
Noah Hahn, M.D. 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT03504163
What this trial is testing

Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

Who this might be right for
Bladder Cancer
Memorial Sloan Kettering Cancer Center 45
Not applicableNot Yet RecruitingNCT07053748
What this trial is testing

Observational Clinical Study on High - Risk NMIBC Patients Choosing Trimodality Bladder - Sparing Therapy

Who this might be right for
High - Risk NMIBC
Peking University First Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06567743
What this trial is testing

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

Who this might be right for
High-Risk Non-Muscle-Invasive Bladder Cancer
CG Oncology, Inc. 325
Not applicableNot Yet RecruitingNCT06982690
What this trial is testing

Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial

Who this might be right for
NMIBCTURBTBladder (Urothelial, Transitional Cell) Cancer+3 more
National Taiwan University Hospital 370
Testing effectiveness (Phase 2)Looking for participantsNCT04752722
What this trial is testing

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Who this might be right for
Superficial Bladder CancerNon-muscle Invasive Bladder Cancer With Carcinoma in Situ
enGene, Inc. 350
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07322263
What this trial is testing

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

Who this might be right for
Bladder CancerNon-Muscle Invasive Bladder Cancer (NMIBC)Urothelial Carcinoma+8 more
Michael A. O'Donnell 174
Testing effectiveness (Phase 2)Study completedNCT04496219
What this trial is testing

Acupuncture for the Treatment of Intravesical BCG-Related Adverse Events in High-Risk Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder Urothelial Carcinoma In SituRecurrent Bladder Urothelial CarcinomaStage 0a Bladder Cancer AJCC v8+3 more
Fred Hutchinson Cancer Center 45
Early research (Phase 1)Study completedNCT02808143
What this trial is testing

Pembrolizumab and BCG Solution in Treating Patients With Recurrent Non-Muscle-Invasive Bladder Cancer

Who this might be right for
Recurrent Bladder CarcinomaStage 0a Bladder Urothelial CarcinomaStage 0is Bladder Urothelial Carcinoma+1 more
Northwestern University 9
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