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Results for “High-Risk Non-Muscle Invasive Bladder Urothelial Carcinoma”

49 trials

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Showing 20 of 49 results

Post-approval studies (Phase 4)Active Not RecruitingNCT04701151
What this trial is testing

NORTH-REG Dwell-Time Study

Who this might be right for
Side Effect of Drug
Jørgen Bjerggaard Jensen 314
Testing effectiveness (Phase 2)Study completedNCT00794950
What this trial is testing

Bacillus Calmette-Guerin Followed by Sunitinib for the Treatment of High Risk Non-muscle Invasive Lower Urinary Tract Urothelial Carcinoma

Who this might be right for
Urinary Tract Urothelial Carcinoma
University of Michigan 43
Testing effectiveness (Phase 2)Looking for participantsNCT07322263
What this trial is testing

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

Who this might be right for
Bladder CancerNon-Muscle Invasive Bladder Cancer (NMIBC)Urothelial Carcinoma+8 more
Michael A. O'Donnell 174
Early research (Phase 1)Active Not RecruitingNCT05768347
What this trial is testing

Intravesical Adoptive Cell Therapy w/ TIL for BCG Exposed High Grade NMIBC

Who this might be right for
Urothelial CarcinomaNon-Invasive Bladder Urothelial Carcinoma
H. Lee Moffitt Cancer Center and Research Institute 9
Not applicableUnknownNCT06324058
What this trial is testing

Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC

Who this might be right for
Bladder Cancer
Huashan Hospital 190
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07808216
What this trial is testing

Toripalimab Combined With Intravesical Gemcitabine as Adjuvant Therapy for High-Risk Non-Muscle-Invasive Bladder Cancer After TURBT

Who this might be right for
Non Muscle Invasive Bladder Cancer
Tianjin First Central Hospital 54
Large-scale testing (Phase 3)Looking for participantsNCT07480356
What this trial is testing

Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder (Urothelial, Transitional Cell) CancerNon-Muscle Invasive Bladder CarcinomaNon-muscle Invasive Bladder Cancer With Carcinoma in Situ
Protara Therapeutics 284
Not applicableEnded earlyNCT04412070
What this trial is testing

Assessement of the Concordance of Genomic Alterations Between Urine and Tissue in High-Risk NMIBC Patients

Who this might be right for
Bladder Cancer
Hopital Foch 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07189793
What this trial is testing

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

Who this might be right for
Urinary Bladder NeoplasmsCarcinoma, Transitional CellCarcinoma in Situ of Bladder+1 more
First Affiliated Hospital of Wenzhou Medical University 106
Testing effectiveness (Phase 2)Active Not RecruitingNCT04706598
What this trial is testing

Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

Who this might be right for
Urinary Bladder NeoplasmsImmunotherapy
Fudan University 25
Testing effectiveness (Phase 2)UnknownNCT05418309
What this trial is testing

Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable: a Multi-center Study

Who this might be right for
High-Risk Non-Muscle Invasive Bladder Urothelial Carcinoma
Tianjin Medical University Second Hospital 63
Testing effectiveness (Phase 2)Study completedNCT02015104
What this trial is testing

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Who this might be right for
Bladder Cancer
National Cancer Institute (NCI) 32
Early research (Phase 1)Active Not RecruitingNCT05843448
What this trial is testing

IDO and PD-L1 Peptide Based Immune-Modulatory Therapeutic (IO102-IO103) in Combination With Pembrolizumab for BCG-Unresponsive or Intolerant, Non-Muscle Invasive Bladder Cancer

Who this might be right for
High Risk Non-Muscle Invasive Bladder Urothelial CarcinomaStage 0a Bladder Cancer AJCC v8Stage 0is Bladder Cancer AJCC v8+1 more
University of California, Davis 6
Testing effectiveness (Phase 2)Looking for participantsNCT05943379
What this trial is testing

RC48-ADC in Combination With Gemcitabine in High Risk NMIBC Subjects

Who this might be right for
NMIBC
RemeGen Co., Ltd. 85
Large-scale testing (Phase 3)Active Not RecruitingNCT06462001
What this trial is testing

BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder Cancer

Who this might be right for
Transitional Cell CarcinomaTransurethral Resection
Nottingham University Hospitals NHS Trust 500
Testing effectiveness (Phase 2)Study completedNCT01939756
What this trial is testing

Intravesical Natural Baobab Oil in the Management of BCG-induced Lower Urinary Tract Symptoms

Who this might be right for
Superficial Bladder CancerLower Urinary Tract Symptoms
Savino M. Di Stasi 50
Testing effectiveness (Phase 2)Looking for participantsNCT06972615
What this trial is testing

Intravesical Chemotherapy in Combination With Systemic Pembrolizumab in NMIBC Unresponsive or Exposed to BCG Therapy

Who this might be right for
Non Muscle Invasive Bladder Cancer
BLATAM 37
Large-scale testing (Phase 3)Looking for participantsNCT05037279
What this trial is testing

Evaluating Safety and Efficacy of Verity-BCG in BCG-naïve Patients With Intermediate and High-risk Non-muscle Invasive Bladder (NMIBC)

Who this might be right for
Bladder CancerBladder Cancer RecurrentNeoplasm Recurrence+3 more
Verity Pharmaceuticals Inc. 540
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07625527
What this trial is testing

Is Prolonged Systemic Immunotherapy Necessary After Achieving Tumor-free Status in Patients With Extensive Transurethrally Unresectable Very-high-risk NMIBC?

Who this might be right for
Bladder (Urothelial, Transitional Cell) CancerNon Muscle Invasive Bladder Cancer
Tianjin Medical University Second Hospital 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07356791
What this trial is testing

Phase II Prospective Cohort Study of Intravesical Recombinant Human Type 5 Adenovirus Injection for Treatment of High-Risk Non-Muscle Invasive Bladder Cancer: Evaluating Efficacy and Safety

Who this might be right for
Bladder (Urothelial, Transitional Cell) Cancer
RenJi Hospital 18
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